PO.BCS01.06 · 生物信息与计算
通过GLORIA远程病理网络改善复杂肿瘤病例的组织病理诊断周转时间
Improving histopathological diagnostic turnaround time through the GLORIA Telepathology Network in complex oncological cases
作者与单位 Authors & Affiliations
摘要 Abstract
中文摘要
引言：在拉丁美洲国家，及时准确的肿瘤诊断在可及性上的差异，导致城市与农村人群之间生存结局的差异。哥伦比亚即为此种情况的典型，每10万居民仅有0.88名病理医生，且肿瘤病理医生数量极为有限，其中大多数集中在大城市。GLORIA远程病理网络的建立旨在通过部署一个连接外围医院与专家中心的数字诊断平台来解决这些不平等问题。通过全切片成像（WSI）和实时远程会诊，GLORIA提高了诊断准确性，缩短了组织病理报告的周转时间，并支持全国范围内肿瘤诊疗的临床决策。本研究旨在描述会诊最频繁的肿瘤类型，并评估远程病理网络实施以来的诊断周转时间。
方法：在哥伦比亚不同地区（Armenia、Pereira、Pasto、Cartagena、Cúcuta和Montería）安装了六台WSI扫描仪（Roche DP200），以实现存在诊断挑战的肿瘤病例的数字化。这些数字切片由专业肿瘤病理医生进行远程审阅和讨论。
结果：在实施的前10个月内，包括数字化中心的逐步整合，共对363例肿瘤病例进行了会诊。会诊最频繁的肿瘤类型为：皮肤肿瘤（14.0%）、妇科肿瘤（10.7%）、乳腺肿瘤（9.6%）和软组织肿瘤（9.4%）。平均诊断周转时间（从病例上传到专家报告）为18小时。
讨论：与传统会诊方法（20天）相比，周转时间的这一缩短反映出显著改善。GLORIA远程病理网络的实施证明了远程病理在缩短诊断延迟方面的关键作用，尤其是在缺乏肿瘤病理医生的地区。通过实现快速专家审阅并促进全国范围的协作，GLORIA为哥伦比亚全境更公平、更及时的肿瘤诊疗做出了贡献。
查看英文原文 English abstract
Introduction: In Latin American countries, disparities in access to timely and accurate oncological diagnoses contribute to differences in survival outcomes between urban and rural populations. Colombia exemplifies this situation, with only 0.88 pathologists per 100,000 inhabitants and a very limited number of oncopathologists, most of whom are concentrated in major cities.The GLORIA Telepathology Network was developed to address these inequities by implementing a digital diagnostic platform that connects peripheral hospitals with expert centers. Through whole-slide imaging (WSI) and real-time remote consultations, GLORIA enhances diagnostic accuracy, reduces turnaround time for histopathological reports, and supports clinical decision-making in oncological care across the country. The aim of this study is to describe the most frequently consulted tumor types and to evaluate the diagnostic turnaround times since the implementation of Telepathology Network.
Methdology: Six WSI scanners (Roche DP200) were installed in different regions of Colombia (Armenia, Pereira, Pasto, Cartagena, Cúcuta, and Montería) to enable the digitalization of oncological cases that present diagnostic challenges. These digital slides are remotely reviewed and discussed with specialized oncopathologists
Results: During the first 10 months of implementation, including the progressive integration of the digitalization centers, a total of 363 oncological cases were interconsulted. The most frequently interconsulted tumor types were: Skin tumors (14.0%), Gynecologic tumors (10.7%), Breast tumors (9.6%) and Soft tissue tumors (9.4%). The average diagnostic turnaround time (from case upload to expert report) was 18 hours.
Discussion: This reduction in turnaround time reflects a substantial improvement compared to traditional consultation methods (20 days). The implementation of the GLORIA Telepathology Network demonstrates the critical role of telepathology in reducing diagnostic delays, particularly in regions lacking access to oncopathologists. By enabling rapid expert review and fostering nationwide collaboration, GLORIA contributes to more equitable and timely oncological care across Colombia.
利益披露 Disclosure
R. Parra-Medina, None..
A. Mosquera-Zamudio, None..
R. Paez, None..
M. Lopez, None..
M. Espinosa, None..
Y. Carlosama Rosero, None..
Y. Poveda, None..
K. Redondo-De Oro, None..
M. Gomez-Suarez, None.