PO.CL04.02 · 临床研究
亚裔美国乳腺癌幸存者的社会心理特征与疼痛管理模式：一项聚类分析
Psychosocial profiles and pain management patterns among Asian American breast cancer survivors: A cluster analysis
该海报暂无可下载的资料
AACR 官方页面
作者与单位 Authors & Affiliations
摘要 Abstract
中文摘要
背景：亚裔美国乳腺癌幸存者是一个具有独特社会心理需求的多样化人群，然而目前基于心理健康状况、疼痛管理观念和社会支持来识别其亚组的研究仍然有限。了解社会心理特征的异质性可能有助于制定文化适宜的幸存者照护方案。本研究旨在识别亚裔美国乳腺癌幸存者中不同的社会心理亚组，并考察各亚组在抑郁症状、疼痛管理态度与障碍、社会影响、生活质量、应对自我效能、孤独感以及感知社会支持方面的差异。
方法：本研究是一项正在进行的、针对亚裔美国乳腺癌幸存者的临床试验的一部分。本次分析仅使用了基线数据，共纳入106名女性。对社会心理变量（包括抑郁症状、癌性疼痛管理的态度与感知障碍、社会影响、自我效能、孤独感和社会支持）进行了K-means聚类分析。通过轮廓分析（silhouette analysis）确定了最优聚类数（k = 3）。采用单因素方差分析（ANOVA）结合Tukey事后检验比较各聚类间的社会心理结局。
结果：出现了三个有意义的聚类。聚类1（有韧性且获得支持的幸存者，N = 30）表现出最低的抑郁症状、最强的社会支持、积极的疼痛态度，以及最高的生活质量和应对自我效能。聚类2（心理脆弱且社会孤立的幸存者，N = 30）表现出最高的抑郁症状、最大的疼痛管理障碍，以及最低水平的应对自我效能、生活质量和感知社会支持，同时孤独感评分最高。聚类3（应对能力中等的幸存者，N = 46）在所有社会心理指标以及对疼痛和疼痛管理障碍的感知态度上均表现为中等水平。所有社会心理与生活质量结局在各亚组间均存在显著差异（p < .001）。
结论：亚裔美国乳腺癌幸存者表现出显著的社会心理异质性。未来文化响应型的定制化干预措施需要针对心理脆弱、社会孤立的亚组，并在幸存者照护中应对情绪困扰、社会联结和疼痛相关态度。研究结果支持在基于技术的幸存者项目中采用聚类导向的个性化策略。
查看英文原文 English abstract
Background: Asian American breast cancer survivors represent a diverse population with unique psychosocial needs, yet limited research has identified subgroups based on psychological well-being, pain management beliefs, and social support. Understanding heterogeneity in psychosocial profiles may inform culturally tailored survivorship care. This study aimed to identify distinct psychosocial subgroups among Asian American breast cancer survivors and examine differences in depressive symptoms, pain management attitudes and barriers, social influence, quality of life, coping self-efficacy, loneliness, and perceived social support among the subgroups.
Methods: This is part of an ongoing clinical trial among Asian American breast cancer survivors. Only the baseline data were used for this analysis. A total of 106 women were included in the analysis. K-means cluster analysis was conducted on psychosocial variables, including depressive symptoms, attitudes, and perceived barriers to cancer pain management, social influence, self-efficacy, loneliness, and social support. The optimal number of clusters (k = 3) was determined by silhouette analysis. One-way ANOVA with Tukey post-hoc tests compared psychosocial outcomes across clusters.
Results: Three meaningful clusters emerged. Cluster 1 (resilient and supported survivors, N = 30) displayed the lowest depressive symptoms, strongest social support, positive pain attitudes, and highest quality of life and coping self-efficacy. Cluster 2 (psychologically vulnerable and socially isolated survivors, N = 30) demonstrated the highest depressive symptoms, greatest pain management barriers, and lowest levels of coping self-efficacy, quality of life, and perceived social support, along with the highest loneliness scores. Cluster 3 (moderately coping survivors, N = 46) showed intermediate levels across all psychosocial indicators and perceived attitudes towards pain and pain management barriers. All psychosocial and quality-of-life outcomes significantly differed across subgroups (p < .001).
Conclusion: Asian American breast cancer survivors demonstrate significant psychosocial heterogeneity. Future culturally responsive, tailored interventions need to target the psychologically vulnerable, socially isolated subgroup, and address emotional distress, social connection, and pain-related attitudes in survivorship care. Findings support cluster-informed personalization strategies in technology-based survivorship programs.
利益披露 Disclosure
D. Kim, None..
J. Baek, None..
S. Ryu, None..
Y. Kim, None..
W. Chee, None..
E. Im, None.