PO.BCS02.01 · 生物信息与计算
DrBioRight:用于癌症数据分析的AI研究助手
DrBioRight: an AI research assistant for cancer data analysis
作者与单位 Authors & Affiliations
摘要 Abstract
中文摘要
我们展示 DrBioRight,这是一个下一代对话式AI平台,通过多智能体大语言模型(LLM)架构简化癌症组学分析。现代测序和成像技术生成海量且复杂的数据集,然而传统的分析工具往往需要大量的计算专业知识。DrBioRight 通过使研究人员能够与系统进行自然语言对话,将复杂的分析任务转化为直观的对话式交互,从而克服了这一障碍。DrBioRight 的聊天机器人驱动界面允许用户搜索和查询数据集、执行多组学分析、获取可解释的洞见,并生成出版级质量的可视化图表——所有这些都可通过简单的提问或指令完成。这种交互模式消除了对编程的需求,降低了高级生物信息学的门槛,使组学研究能够为更广泛的科学界所用。主要功能包括:(i) 面向RNA-seq、蛋白质组学、单细胞、空间和临床基因组数据的LLM驱动对话式分析;(ii) 汇集自TCGA、CPTAC、DepMap及其他公共数据库的精选高性能癌症组学数据存储库;(iii) 一个可扩展的应用商店,集成了生物信息学软件包、流程和自定义工具;(iv) 实时任务预测、工作流程指导和故障排除;(v) 用于在研究团队间共享分析和结果的协作工作区功能;(iv) 社区驱动的可扩展性,能够无缝集成新的数据集、模块和分析框架。通过从传统的技术界面转向交互式对话范式,DrBioRight 充当一个智能研究助手。它使复杂的组学分析普及化,增强协作发现,并加速整个癌症研究界的转化研究。
查看英文原文 English abstract
We present DrBioRight, a next-generation conversational AI platform that streamlines cancer omics analysis through a multi-agent large language model (LLM) architecture. Modern sequencing and imaging technologies generate vast and complex datasets, yet conventional analysis tools often require substantial computational expertise. DrBioRight overcomes this barrier by enabling researchers to engage in natural language dialogue with the system, transforming intricate analytical tasks into intuitive, conversational interactions. DrBioRight's chatbot-driven interface allows users to search and query datasets, execute multi-omics analyses, access interpretable insights, and generate publication-quality visualizations-all through simple questions or commands. This interaction model removes the need for programming, lowering the barrier to advanced bioinformatics and making omics research accessible to a broader scientific community. Key features include: (i) LLM-powered conversational analysis for RNA-seq, proteomics, single-cell, spatial, and clinical-genomic data ; (ii) A curated, high-performance cancer omics datastore drawing from TCGA, CPTAC, DepMap, and other public repositories; (iii) An extensible App Store integrating bioinformatics software packages, pipelines, and custom tools; (iv) Real-time task prediction, workflow guidance, and troubleshooting; (v) Collaborative workspace functionality for sharing analyses and results across research teams; (iv) Community-driven extensibility, enabling seamless integration of new datasets, modules, and analytical frameworks. By shifting from traditional technical interfaces to an interactive conversational paradigm, DrBioRight functions as an intelligent research assistant. It democratizes the use of complex omics analytics, enhances collaborative discovery, and accelerates translational research across the cancer research community.
利益披露 Disclosure
H. Liang,
Precision Scientific Stock.