PO.PS01.05 · 人群科学
美国人群对HBV、HCV及其与癌症关联的认知
Population awareness of HBV, HCV, and their association with cancer in the US
作者与单位 Authors & Affiliations
摘要 Abstract
中文摘要
引言：据估计，2025年美国将有42,240例肝癌新发病例和30,090例肝癌死亡病例。慢性乙型和丙型肝炎感染是肝癌的主要风险因素，但公众对其致癌潜力的认知仍然有限。了解人群层面对这一关联的认知，对于改善预防、筛查和疫苗接种工作至关重要。我们检查了美国成年人中乙型或丙型肝炎与癌症关联认知的患病率，以及社会人口学特征与该认知之间的关联。
方法：我们分析了健康信息全国趋势调查（HINTS 7）的数据，这是一项于2024年开展的具有全国代表性的美国成年人调查。结局指标为对乙型或丙型肝炎与癌症关联的认知（是/否）。该结局通过以下问题评估：“您认为乙型肝炎病毒（也称为Hep B或HBV）或丙型肝炎病毒（也称为Hep C或HCV）会导致癌症吗？”估算了受访者中对乙型或丙型肝炎作为癌症病因认知的加权患病率。采用加权多变量logistic回归模型估算社会人口学特征（年龄、性别、种族/族裔、婚姻状况、教育水平、家庭收入、城乡状况、就医次数和健康状况）与乙型或丙型肝炎和癌症关联认知之间的关联。
结果：共纳入7,278名参与者进行分析，其中51%为18-48岁人群，52%为女性，61%为非西班牙裔白人，56%为已婚，33%为大学毕业生，27%家庭年收入<35,000美元。其中，26.9%的人知道乙型或丙型肝炎会导致癌症。与18-49岁受访者相比，≥65岁者较不了解乙型或丙型肝炎会导致癌症（aOR=0.57；95% CI：0.44-0.76）。同样，与已婚受访者相比，离婚/分居/丧偶者较不了解乙型或丙型肝炎会导致癌症（aOR=0.73；95% CI：0.53-0.98）。然而，与高中及以下学历者相比，大学毕业的受访者更了解乙型或丙型肝炎会导致癌症（aOR=2.03；95% CI：1.39-2.95）。
结论：尽管美国肝癌负担日益加重，但人群对乙型或丙型肝炎病毒会导致癌症的认知仍然较低，且在不同社会人口学群体之间差异显著。这些发现提示，美国人群中持续存在关键的信息/知识缺口，需要针对性的、符合健康素养的教育干预措施，以提高公众对可预防癌症风险的认知。
查看英文原文 English abstract
Introduction: It is estimated that there will be 42,240 new cases and 30,090 deaths of liver cancer in the US in 2025. Chronic hepatitis B and C infections are the leading risk factors of liver cancer, yet public awareness of their oncogenic potential remains limited. Understanding population-level awareness of this link is essential for improving prevention, screening, and vaccination efforts. We examined the prevalence and association between sociodemographic characteristics and awareness of the link between hepatitis B or C and cancer among U.S. adults.
Methods: We analyzed data from the Health Information National Trends Survey (HINTS 7), a nationally representative survey of U.S. adults conducted in 2024. The outcome was awareness about the link between hepatitis B or C and cancer (yes/no). The outcome was accessed with the question “Do you think the Hepatitis B virus (also known as Hep B or HBV), or Hepatitis C virus (also known as Hep C or HCV) can cause cancer?” Weighted prevalence of awareness of hepatitis B or C as a cause of cancer was estimated among respondents. A weighted multivariable logistic regression model was used to estimate the association between sociodemographic characteristics (age, gender, race/ethnicity, marital status, education level, household income, rural-urban status, # of healthcare visits, and health status) and awareness of the link between hepatitis B or C and cancer.
Results: A total of 7,278 participants were included in the analysis, including 51% of individuals aged 18-48 years, 52% of female, 61% of non-Hispanic White, 56% of married, 33% of college graduates, and 27% with household annual income of <$35,000. Of these, 26.9% were aware that hepatitis B or C can cause cancer. Compared with respondents aged 18-49 years, those aged ≥65 years were less likely to know that hepatitis B or C can cause cancer (aOR=0.57; 95% CI: 0.44-0.76). Similarly, compared to respondents who were married, those who were divorced/separated/widowed were less likely to know that hepatitis B or C can cause cancer (aOR=0.73; 95% CI: 0.53-0.98). However, respondents who were college graduates were more likely to know hepatitis B or C can cause cancer (aOR=2.03; 95% CI: 1.39-2.95) compared with those with high school diploma or less.
Conclusion: Despite the growing burden of liver cancer in the US, population awareness that hepatitis B or C viruses can cause cancer remains low and varies substantially across sociodemographic groups. These findings suggest critical information/knowledge gaps persist across the U.S. population and call for targeted, health-literacy-appropriate educational interventions to enhance public awareness of preventable cancer risks.
利益披露 Disclosure
E. Adjei Boakye, None..
C. Dagli, None..
M. So, None..
P. G. Patel, None..
M. Nair, None..
J. Fokom Domgue, None.