PO.ADV02 · 患者倡导
数字空间分析如何改变肺癌抗击之战
How digital spacial profiling is changing the fight against lung cancer
作者与单位 Authors & Affiliations
摘要 Abstract
中文摘要
肺癌是全球癌症死亡的首要原因，尽管免疫疗法和靶向疗法已带来变革性影响，但它们仅对大约五分之一的患者有效。在此之前，我们一直无法可靠地预测谁将产生应答，直到现在。数字空间分析（Digital Spatial Profiling）使我们能够解读肿瘤微环境：即由免疫细胞、癌细胞和支持性结构组成的复杂生态系统，它最终决定了一种治疗是成功还是失败。
查看英文原文 English abstract
Lung cancer is the leading cause of cancer death globally, and while immunotherapies and targeted therapies have been transformative, they only work in roughly 1 in 5 patients. We have not been able to reliably predict who will respond, until now. Digital Spatial Profiling allows us to read the tumour microenvironment: the complex ecosystem of immune cells, cancer cells, and supporting structures that ultimately determines whether a treatment succeeds or fails.