PO.CL09.03 · 临床研究

针对肿瘤急症的周末放疗:单机构的适应证与实践模式分析

Weekend radiotherapy for oncologic emergencies: A single-institution analysis of indications and practice patterns

海报缩略图:针对肿瘤急症的周末放疗:单机构的适应证与实践模式分析
编号 5427 展板 17 时间 4/21 09:00–12:00 区域 Section 49 主讲 Ahmed Allibhai, No Degree
分会场 Retrospective Observational Studies
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作者与单位 Authors & Affiliations

Ahmed Allibhai, Asiyah Allibhai

Holy Trinity School, Richmond Hill, ON, Canada

摘要 Abstract

中文摘要
目的:肿瘤并发症可能需要在标准工作时间之外进行紧急放疗(RT)。本研究记录了在单一机构中于周末/预定假日接受放疗的患者的发生率、适应证、放疗剂量/分割及结局。 方法:回顾性识别2022年1月至2024年12月期间在周末(周六、周日或长周末假日)接受放疗的患者。收集并分析患者人口学特征、原发癌诊断、临床适应证、治疗部位、剂量/分割、住院状态、治疗完成情况及生存情况。 结果:三年间,122例患者接受了紧急周末放疗。中位年龄为67岁(39-98);63.1%为男性,66.4%为住院患者。患者最常表现为肺(25.4%)、胃肠道(23.8%)和血液系统(18.0%)恶性肿瘤。紧急周末放疗的前三位适应证包括脊髓压迫(38.9%)、消化道出血(20.7%)或阻塞性气道/肺疾病(7.6%)。最常见的放疗方案为20 Gy分5次(80.3%),大多数患者接受两天治疗(54.1%)。6例患者(4.9%)因临床恶化未完成治疗疗程。一个月死亡率为13.1%,三个月死亡率为36.9%。 结论:周末放疗主要用于处理明确识别的肿瘤急症,如脊髓压迫和肿瘤相关出血。住院患者比例高及可观的短期死亡率反映了需要紧急干预的晚期疾病负担。这些发现证明了周末放疗服务的重要性和发生率,并为帮助制定人员配置和资源分配以及机构政策提供了证据。
查看英文原文 English abstract
Purpose: Oncologic complications can arise that require emergency radiotherapy (RT) outside of standard working hours. This study documents the incidence, indications, RT dose/fractionation and outcomes for patients receiving RT on weekends/scheduled holidays at a single institution. Methods: Patients receiving RT on weekends (Saturday, Sunday, or long weekend holidays) from January 2022 through December 2024 were identified retrospectively. Patient demographics, primary cancer diagnosis, clinical indication, treatment site, dose/fractionation, inpatient status, treatment completion, and survival were collected and analyzed. Results: Over three years, 122 patients received emergency weekend RT. Median age was 67 years (39-98); 63.1% male, 66.4% inpatients. Patients most commonly presented with lung (25.4%), gastrointestinal (23.8%), and hematologic (18.0%) malignancies. The top three indications for emergency weekend RT included spinal cord compression (38.9%), GI bleeding (20.7%), or obstructive airway/lung disease (7.6%). The most common RT regimen was 20 Gy in 5 fractions (80.3%), with most patients receiving two days of treatment (54.1%). Six patients (4.9%) did not complete their course of treatment owing to clinical deterioration. One-month mortality was 13.1% and three-month mortality was 36.9%. Conclusions: Weekend RT is predominantly used to manage well-identified oncologic emergencies such as spinal cord compression and tumor-related bleeding. The high inpatient proportion and substantial short-term mortality reflect advanced disease burden requiring urgent intervention. These findings demonstrate the importance and incidence of weekend radiotherapy services and provide evidence to help inform staffing & resource allocation as well as institutional policies.
利益披露 Disclosure
A. Allibhai, None.

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