PO.PR01.05 · 预防研究
iCCaRE联盟虚拟现实助手（ViRA）在前列腺癌诊断时点支持黑人男性的新型应用
Novel application of the iCCaRE consortium virtual reality assistant (ViRA) to support Black men at the point of prostate cancer diagnosis
作者与单位 Authors & Affiliations
摘要 Abstract
中文摘要
背景：黑人男性承担着不成比例的前列腺癌（CaP）负担，并常在前列腺癌诊断时点（PPCD）经历显著的心理社会困扰。许多人报告情绪震惊、不确定感以及获得文化胜任指导的机会有限，这可能对治疗决策和长期生存质量产生负面影响。为应对这些需求，我们开发了PPCD虚拟现实助手（ViRA），这是一种与黑人CaP幸存者共同设计的沉浸式、AI赋能的干预措施。ViRA在虚拟现实环境中提供量身定制的心理肿瘤学支持、情绪指导以及健康社会决定因素（SDOH）的导航。本研究评估了PPCD ViRA的可行性、可接受性和可用性（NCT06535802）。
方法：ViRA通过与幸存者的结构化七步共同设计流程开发，整合了移动沉浸式技术、SDOH导航以及基于文化的心理肿瘤学内容。个性化通过AI驱动的预测分析和推荐引擎实现。Alpha测试在10名参与者（7名团队成员和3名黑人CaP幸存者）中评估了初步的可用性和可接受性。在佛罗里达州对24名黑人男性进行的Beta测试考察了可行性和初步疗效。
结果：ViRA的演示可查看（https://www.youtube.com/watch?v=1mI-HS5R6sk）。Alpha测试表明其可用性强、情绪参与积极，并在增强PPCD支持方面展现出明确的前景。在Beta测试中，参与者年龄各异；大多数已婚（58.3%），持有学士学位（45.8%），已退休（45.8%），并有癌症家族史（83.3%）。ViRA的使用与参与度提高和困扰减轻相关。总体而言，74%的参与者将ViRA评为"优秀"，其余评为"良好"或"很好"。超过90%的参与者报告"非常满意"，其余表示满意。
结论：研究结果表明PPCD ViRA在支持诊断时点黑人男性方面具有高可行性、可接受性和文化相关性。经验教训凸显了文化嵌入式设计、情绪时机、社区共创、灵活的交付形式以及强有力的社区伙伴关系对推进数字健康公平的必要性。为确立临床效用和实施就绪性而进行的完善和更大规模验证正在进行中（NCT07126548）。
查看英文原文 English abstract
Background: Black men carry a disproportionate prostate cancer (CaP) burden and often experience significant psychosocial distress at the point of prostate cancer diagnosis (PPCD). Many report emotional shock, uncertainty, and limited access to culturally competent guidance, which can negatively affect treatment decisions and long-term survivorship. To address these needs, we developed the PPCD Virtual Reality Assistant (ViRA), an immersive, AI-enabled intervention co-designed with Black CaP survivors. ViRA delivers tailored psycho-oncology support, emotional guidance, and navigation of social determinants of health (SDOH) within virtual reality environments. This study evaluated the feasibility, acceptability, and usability of the PPCD ViRA (NCT06535802).
Methods: ViRA was developed through a structured, seven-step co-design process with survivors, integrating mobile immersive technologies, SDOH navigation, and culturally grounded psycho-oncology content. Personalization was enabled through AI-driven predictive analytics and a recommendation engine. Alpha testing assessed initial usability and acceptability among 10 participants (seven team members and three Black CaP survivors). Beta testing with 24 Black men in Florida examined feasibility and preliminary efficacy.
Results: A demonstration of ViRA is available (https://www.youtube.com/watch?v=1mI-HS5R6sk). Alpha testing indicated strong usability, positive emotional engagement, and clear promise for enhancing support at the PPCD. In Beta testing, participants varied in age; most were married (58.3%), held a bachelor's degree (45.8%), were retired (45.8%), and had a family history of cancer (83.3%). ViRA use was associated with increased engagement and reduced distress across participants. Overall, 74% rated ViRA as “excellent,” while the remainder rated it as “good” or “very good.” More than 90% reported being “very satisfied,” with the rest indicating satisfaction.
Conclusions: Findings demonstrate high feasibility, acceptability, and cultural relevance of the PPCD ViRA for supporting Black men at diagnosis. Lessons learned highlight the need for culturally embedded design, emotional timing, community co-creation, flexible delivery formats, and strong community partnerships to advance digital health equity. The refinement and larger-scale validation to establish clinical utility and readiness for implementation is ongoing (NCT07126548).
利益披露 Disclosure
F. T. Odedina, None..
C. Williams, None..
J. Melton, None..
M. Fudge, None..
Q. Wimberly, None.