PO.PS01.11 · 人群科学
在NCI中心为佛罗里达癌症患者实施一款交互式临床试验教育与决策工具
Implementation of an interactive clinical trials education and decision tool for Florida cancer patients at an NCI Center
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摘要 Abstract
中文摘要
背景：CHOICES决策辅助工具（DA）是一款基于证据的、交互式的教育和决策支持工具（提供英语和西班牙语版本），面向癌症患者，介绍参与癌症临床试验（CCTs）的相关内容。作为ACT WONDERS研究（一项旨在增加多样化患者向CCTs转诊和入组的多层次干预）的一部分，该网站向居住在服务区内七个地理界定的研究干预区的Moffitt癌症中心新患者开放。CHOICES DA的特色包括CCTs相关事实等教育内容、关于CCT参与的价值观澄清工具，以及关于CCT参与的患者叙述。
方法：符合条件的患者能够通过患者门户访问该网站，并收到一封包含说明和网站链接的电子邮件。退出网站时，患者被邀请完成一项可选的5项调查，内容涉及CCT主观知识（1-7分制）、与医务人员讨论CCTs的准备程度（1-7分）、CCT决策就绪度（1-7分）、有用性（1-10分）以及对网站的满意度（1-10分）。将平均分重新换算为100%以便比较。持续监测使用指标。
结果：在干预启动后的第一年（2024年9月17日至2025年10月2日），2,340名符合条件的患者中有550名（24%）访问了CHOICES DA。在浏览该网站的550名符合条件患者中，种族人口构成为：白人37%（n=203）；黑人4%（n=27）；其他种族4%（n=23）；未报告54%（n=297）。族裔构成为11%（n=61）西班牙裔/拉丁裔，33%（n=181）非西班牙裔/拉丁裔，56%（n=308）未知。平均年龄为65岁（范围56-73）。10%的用户至少再次访问过该网站。13%的患者浏览了西班牙语网站。45名（8%）患者完成了调查。CCT自评知识平均为84%，CCT决策就绪度为83%，与医生讨论CCTs的就绪度为88.6%。网站有用性和满意度的平均值分别为86%和85%。
结论：研究结果表明，CHOICES DA可以利用患者现有的沟通渠道，在高流量肿瘤诊疗环境中便捷实施。完成调查者对其CCT知识、讨论和决策CCT参与的就绪度以及网站满意度和有用性给予了高度评价。CHOICES DA还将在实施后两年时间点进行评估，未来的分析将考察其对癌症中心CCT入组的影响。
查看英文原文 English abstract
Background: CHOICES Decision Aid (DA) is an evidence-based, interactive, education and decision-making support tool (available in English and Spanish) for cancer patients about participation in cancer clinical trials (CCTs). As part of the ACT WONDERS study, a multi-level intervention aimed at increasing referral and enrollment of diverse patients to CCTs, the website was made accessible to new Moffitt Cancer Center patients residing in seven geographically defined study intervention zones in the catchment area. CHOICES DA features education content such as facts about CCTs, values clarification tools on CCT participation, and patient narratives about CCT participation.
Method: Eligible patients were able to access the site via patient portal and received an email with a description and website link. Upon site exit, patients were asked to complete an optional 5-item survey about subjective CCT knowledge (1-7 scale), preparedness to talk with providers about CCTs (1-7), CCT decision readiness (1-7), and usefulness (1-10), and satisfaction with the site (1-10). Mean scores were re-scaled to 100% for comparison. Usage metrics were continuously monitored.
Results: In the first year following intervention launch (September 17, 2024 - October 2, 2025), 550 of 2,340 eligible patients (24%) visited CHOICES DA. Of 550 eligible patients who viewed the site, race demographics were: white 37% (n=203); Black 4% (n=27); other race 4% (n=23); not reported 54% (n=297). Ethnicity was 11% (n=61) Hispanic/Latino, 33% (n=181) non-Hispanic/Latino, and 56% (n=308) unknown. Mean age was 65 (range 56-73). 10% of users returned to the site at least once. 13% of patients viewed the Spanish site. 45 (8%) patients completed the survey. Mean self-rated CCT knowledge was 84%, readiness to decide about CCTs was 83%, and readiness to discuss CCTs with a doctor was 88.6%. Mean website usefulness and satisfaction were 86% and 85%, respectively.
Conclusion: Findings suggest CHOICES DA could be readily implemented in a high-volume oncology care setting leveraging existing communication channels available to patients. Survey completers gave high ratings to their CCT knowledge and readiness to discuss and make decisions about participation in CCTs, as well as website satisfaction and usefulness. CHOICES DA will also be evaluated at the two-year post-implementation time point, and future analyses will examine the impact on CCT enrollment at the cancer center.
利益披露 Disclosure
S. T. Vadaparampil, None..
L. N. Fuzzell, None..
E. S. Tapia-Kwan, None..
Y. Zhao, None..
R. Amorrortu, None..
D. Rollison, None..
M. Byrne, None.