PO.PS01.10 · 人群科学
社会支持模式与西班牙裔乳腺癌生存者健康相关生活质量的关联
Association of social support patterns on health-related quality of life among Hispanic breast cancer survivors
作者与单位 Authors & Affiliations
摘要 Abstract
中文摘要
目的:社会支持影响西班牙裔乳腺癌生存者的健康相关生活质量(HRQoL),但既往研究尚未考察社会支持的哪些维度组合会影响HRQoL。因此,我们考察了社会支持特征(profile)与西班牙裔乳腺癌生存者HRQoL之间的关联。
方法:通过佛罗里达癌症登记处(Florida Cancer Registry)的招募流程,招募年龄20岁及以上、至少在6个月前被诊断为乳腺癌、居住在中佛罗里达地区、能够阅读或使用英语或西班牙语的西班牙裔女性,开展一项基于人群、考察西班牙裔内部HRQoL差异的研究。使用19条目的医学结局研究(Medical Outcomes Study)问卷评估社会支持。以四个维度(情感支持、实质支持、情感慰藉、社交网络)作为特征指标,采用潜在特征分析(Latent Profile Analysis)探索不同的社会支持模式。使用AIC和BIC确定模型拟合度。采用癌症治疗功能评估-乳腺(FACT-B)评估HRQoL。使用多变量回归模型比较各特征之间的FACT-B评分。
结果:在2023年9月至2025年10月招募的583名女性中,560名完成了社会支持和HRQoL评估的女性被纳入分析。平均年龄为58.9±11.9岁,自诊断以来的平均时间为4.1±2.0年。共出现五种支持特征:各维度支持均低(8.0%)、平均水平支持(16.6%)、高于平均水平支持(18.4%)、情感慰藉/社交支持高但实质支持低(7.1%)以及中等偏高支持(49.8%)。在校正诊断时年龄、西班牙裔来源、BMI、种族、多重共病、收入、教育程度、功能状态、在美居住年数和当前年龄后,我们发现特征4(beta = 15.34,p = 0.001)和特征5(beta = 19.19,p < 0.001)中的女性与特征1相比FACT-B评分显著更高。特征2和特征3与特征1无显著差异。
结论:本研究在西班牙裔乳腺癌女性中识别出五种不同的社会支持特征,并表明较高水平的情感慰藉和社交支持与更好的HRQoL相关,凸显了社会资源在生存者结局中的关键作用。这些发现强调需要开展文化适配的干预措施,以强化情感和社交网络,从而改善生活质量。资助:佛罗里达乳腺癌基金会科学研究基金(Florida Breast Cancer Foundation Scientific Research Grant)。
查看英文原文 English abstract
Objectives: Social support influences health-related quality of life (HRQoL) among Hispanic breast cancer survivors, but prior research has not examined which combination of dimensions of social support shapes HRQoL. Thus, we examined the association of social support profiles with HRQoL among Hispanic breast cancer survivors.
Methods: Hispanic women aged 20 and older, diagnosed with breast cancer at least six months earlier, residing in Central Florida, and able to read or speak English or Spanish were recruited via the Florida Cancer Registry's recruitment procedure for a population-based study examining intra-Hispanic disparities in HRQoL. Social support was assessed using the 19-item Medical Outcomes Study questionnaire. Latent Profile Analysis was conducted to explore distinct social support patterns with the four (emotional, tangible, affective, social network) domains as profile indicators. Model fit was determined using AIC and BIC. Functional Assessment of Cancer Therapy - Breast (FACT-B) assessed HRQoL. A multivariable regression model compared FACT-B scores across the identified profiles.
Results: Among 583 women recruited during September 2023 to October 2025, 560 women who completed the social support and HRQoL assessments were included in the analysis. Mean age was 58.9 ±11.9 years, and mean time since diagnosis was 4.1 ±2.0 years. Five support profiles emerged: low support across domains (8.0%), average support (16.6%), above average support (18.4%), high in affection/social support but low tangible support (7.1%), and moderately high support (49.8%). After controlling for age at diagnosis, Hispanic origin, BMI, race, multimorbidity, income, education, functionality, years living in the USA, and current age, we found that women in Profile 4 (beta = 15.34, p = 0.001) and Profile 5 (beta = 19.19, p < 0.001) had significantly higher FACT-B scores compared to those in Profile 1. Profiles 2 and 3 did not differ significantly from Profile 1.
Conclusions: This study identified five distinct social support profiles among Hispanic women with breast cancer and demonstrated that higher levels of affective and social support are associated with better HRQoL, underscoring the critical role of social resources in survivorship outcomes. These findings highlight the need for culturally tailored interventions that strengthen emotional and social networks to improve quality of life. Funding: Florida Breast Cancer Foundation Scientific Research Grant.
利益披露 Disclosure
B. D. Sukhu, None..
J. Chung, None..
L. Palomino, None..
B. Schlosser, None..
A. Pena, None..
E. Lee, None.