PO.CH01.07 · 化学
Computational, Technological, and Mechanistic Advances
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- 975 975 Deep learning-based screening and design of novel therapeutics that reverse cancer-associated transcriptional phenotypes Jing Xing, Mingdian Tan, Dmitry Leshchiner, Mengying Sun, Shreya Paithankar, Rama Shankar, Erika Lisabeth, Bilal Aleiwi, Ruoqiao Chen, Matthew Giletto, Richard Neubig, Samuel So, Edmund Ellsworth, Mei-Sze Chua, Jiayu Zhou, Bin Chen
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- 986 986 Silyl ethers analogs of SN-38 with unique blue-fluorescent properties exhibit potent anti-cancer activity through topoisomerase I inhibition Sanika Vaidya, Ashley Mo, Alyssa Yee-Xin Chia, Katelyn Li, Shreya Somani, Isabella Lo, Lekhya Menta, Gary Johanning, Feng Wang-Johanning, Edward Njoo
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- 988 988 Synthesis, characterization, and biological evaluation of polyisoprenylated phosphonyl ester inhibitors on triple-negative breast cancer Joshua Kofi Ablordeppey, Kweku Ofosu-Asante, Amarender Burra, Jahnissi Odoom, Desmond Kwakye, Nazarius S. Lamango
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- 992 992 A novel targeted protein degradation platform based on internalization-enhancing peptide for lysosomal degradation of cell-surface proteins Dae Young Kim, Dahye Sim, Daeho Park, Yujin Park, Hee Young Kang, Hoil Choi
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- 1000 1000 Stereocontrolled synthesis and evaluation of functionalized lactams as potential anti-triple-negative breast cancer agents Leila Rahimian, Tolulope Omolekan, Ojasvi Dutta, Konstantin G. Kousoulas, Timothy K. Beng, Jean C. Chamcheu
- 1001 1001 Targeting regulation of F-actin in cutaneous T-cell lymphoma: Synergistic inhibition of p38beta with p38gamma inhibitors Xu Hannah Zhang, Jack Hsiang, Markus Kalkum, Jun Wu, Steven T. Rosen
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- 1003 1003 Targeted co-delivery of gemcitabine and atRA via a GSH-responsive mutual prodrug enhances cytotoxicity through redox imbalance and Pin1 inhibition Nanhee Song, Ilseob Kim, Chnagjin Lim, Dongwon Lee, Sun Il Choi, Yun-Hee Kim
