Therapies Targeting Metastasis

• 2226 · PDF 胰腺癌恶性腹水的新型靶向疗法 Novel targeted therapies for malignant ascites in pancreatic cancer Kuntal Halder, Ruben Munoz, Wei Lin, Annie Yang, Yanghee Woo, Erkut Borazanci, Haiyong Han, Daniel D Von Hoff
• 2227 2227 通过西达本胺及化疗免疫疗法选择性清除衰老的癌症相关成纤维细胞治疗转移性胰腺癌：2期临床试验结果（PANDA-1706） Selectively eliminating senescent cancer-associated fibroblasts via chidamide and chemo-immunotherapy in metastatic pancreatic cancer: phase 2 clinical trial results (PANDA-1706) Tianxing Zhou, Jingrui Yan, Jihui Hao
• 2228 · PDF 生物场疗法通过调控转移级联的多个步骤抑制胰腺癌侵袭和转移 Biofield therapy inhibits pancreatic cancer invasion and metastasis by modulating multiple steps of metastatic cascade Peiying Yang, Sharmistha Chakraborty, Phuong Nguyen, Defeng Deng, Amanda Eckstrom, Andrew Cusimano, Daoyan Wei, Lorenzo Cohen
• 2229 · PDF RIPK2和CDK2在前列腺癌细胞中形成一个可靶向的正反馈环 RIPK2 and CDK2 form a targetable positive feedback loop in prostate cancer cells Ahmed Elgehama, Jaceline Pires Sanches Sanches, Lili Guerra, Wei Yang
• 2230 · PDF CXCR4和CB2受体激动剂联合治疗减少前列腺癌生长和转移 Combined treatment with agonists for CXCR4 and CB2 receptors reduces prostate cancer growth and metastasis Nakea Michelle Pennant, Alifiani Bonita Hartono, Shiqin Liu, Sidharth Paparaju, Chung Lee, Christopher Massey, Tanya Ivanova Stoyanova, Cimona V. Hinton
• 2231 · PDF 使治疗耐药的缺氧转移性黑色素瘤细胞重新恢复敏感性 Resensitizing therapy-resistant anoxic metastatic melanoma cells Gustavo Untiveros, Daryl Forney, Mariella Andrews, Tekaswini Kannan, Luigi Strizzi
• 2232 · PDF 研究在黑色素瘤分子亚型中联合抑制RAF、MEK和FAK Investigating the combined inhibition of RAF, MEK, and FAK in melanoma molecular subtypes Jared Almazan
• 2233 · PDF 黑色素的新型抗癌机制：对癌细胞黏附、存活和迁移的影响 Novel anticancer mechanisms of melanin: Effects on cancer cell adhesion, survival, and migration Dorie Liu, Wei Zhu
• 2234 · PDF 结合原始人类生长因子NME7-AB的抗体阻断其与MUC1*生长因子受体的相互作用以抑制癌症生长和转移 Antibodies that bind to primitive human growth factor NME7-AB block interaction with MUC1* growth factor receptor to inhibit cancer growth and metastasis Cynthia Carol Bamdad, Benoit J. Smagghe, Mark G. Carter, Kevin R. Yi, Michael J. Nash, Trevor J. Grant, Daniel S. Miller, Natalie K. Miller, Andrew K. Stewart
• 2235 · PDF 拦截转移：通过多模态基础模型进行8步CRISPR设计 Intercepting metastasis: 8-step CRISPR design via multi-modal foundation models Fahad Kiani
• 2236 · PDF 评估新型药用化合物对肝癌的治疗效果 Evaluation of novel medicinal compounds for therapeutic efficacy against liver cancer Aarya M. Tripathi, Veerababu Nagati, Yamile AbuchardAnaya, Kaylee Renteria, Denise Soto, Miguel Salazar, Subhash C. Chauhan, Debasish Bandyopadhyay
• 2237 · PDF 新型MACC1转录抑制剂通过降低NFκB信号通路减少转移形成 Novel MACC1 transcriptional inhibitor act via reduced NFκB signaling pathway to reduce metastasis formation Ulrike S. Stein
• 2238 · PDF 三萜类薯蓣皂苷元对肺癌细胞的抗转移特性 Anti-metastatic properties of the triterpene diosgenin on lung carcinoma cells Laurie Mar Santos, Edwin Figueroa, Juan Figueroa, Yamixa Delgado, Daraishka Pérez, Yancy Ferrer
• 2239 · PDF 转钴胺素受体CD320是转移性三阴性乳腺癌的治疗靶点 The transcobalamin receptor, CD320, is a therapeutic target for metastatic triple negative breast cancer Joanne Tejero, Felicia Lazure, Stanislav Drapela, Eduardo Miranda, Nadir Sarigul, Devesh Raizada, Didem Ilter, Ana Gomes
• 2240 · PDF 抑制STAT3和PARP1通过细胞骨架重塑减少TNBC侵袭 Inhibition of STAT3 and PARP1 reduces TNBC invasion through cytoskeletal remodeling Arielle McGlone, Ali Andalibi, Pranabananda Dutta
• 2241 · PDF Galectin 1作为激素驱动的乳腺重塑和早期播散的调控因子及其在乳腺癌中的治疗潜力 Galectin 1 as a regulator of hormone driven mammary remodeling and early dissemination with therapeutic potential in breast cancer Magali Berton, Ramiro Perrotta, Luis Valencia Salazar, Tomás Dalotto Moreno, Yamil D. Mahmoud, Juan Manuel Perez Saez, Sabrina Gatto, Rosa Morales, Julio Aguirre-Ghiso, Gabriel A. Rabinovich, Mariana Salatino
• 2242 · PDF 双重TTK/PLK1抑制联合G-CSF治疗协同抑制三阴性乳腺癌的转移进展 Dual TTK/PLK1 inhibition combined with G-CSF treatment synergistically suppresses metastatic progression in triple-negative breast cancer Sunwoong Kim, Hanyoung Kim, Sung-Dae Cho, Jaehan Lee, Mi Kyung Park, Minkyung Kang, Seunghyun Ma, Hee-Joo Choi, Jeong-Yeon Lee
• 2243 · PDF 拉索昔芬是雌激素受体阳性乳腺癌的一种保护骨骼的治疗选择 Lasofoxifene is a bone protective treatment option for estrogen receptor positive breast cancers Emily Kate Zboril, David C. Boyd, Rachel K. Myrick, Nina Dashti-Gibson, Faith E. Parker, Carson Walker, Amy Olex, Chuck Harrell
• 2244 · PDF 抑制促转移激酶网络以治疗耐药性三阴性乳腺癌 Pro-metastatic kinase network inhibition to treat drug-resistant triple-negative breast cancer Margarite Matossian, Madeline Henn Bungert, Kent Schechter, Long Chi Nguyen, Michael East, Denis O. Okumu, Rita Nanda, Gary L. Johnson, Marsha R. Rosner
• 2245 · PDF DNMTi与PARPi联合抑制三阴性乳腺癌中异常的Wnt/beta-catenin信号传导和tenascin-C通路、癌症干性及转移 DNMTi in combination with PARPi inhibits aberrant Wnt/beta-catenin signaling and tenasin-C pathways, cancer stemness and metastasis in triple negative breast cancer Lora Stojanovic, Kaushlendra Tripathi, Zahra Gohari, Julia L. Rutherford, Saranya Rajendran, Tara X. Metcalfe, Shu Zhang, Stephen B. Baylin, Michael Topper, Kenneth P. Nephew, Feyruz V. Rassool
• 2246 2246 抑制GLUT3通过TEAD-VASP-Actin轴调节细胞力学，降低三阴性乳腺癌细胞的转移潜能 GLUT3 inhibition reduces metastatic potential of triple-negative breast cancer cells by modulating cell mechanics via the TEAD-VASP-Actin axis Seeun Oh, Wonkyung Lee, Song Kim, Donghoon Yoon, Jun-Yong Choe, Tae-Hyung Kim
• 2247 · PDF 细胞内补体信号在S1P/S1PR1介导的炎症小体激活与肿瘤转移中发挥关键作用 Intracellular complement signaling plays a critical role in s1p/s1pr1 mediated inflammasome activation and tumor metastasis Salih Gencer, Alhaji H. Janneh, Natalia Oleinik, Charles Chalfant, Besim Ogretmen
• 2248 · PDF 抑制线粒体抗氧化反应可阻断小儿骨肉瘤的离体肺定植 Inhibition of the mitochondrial antioxidant response blocks ex vivo lung colonization in pediatric osteosarcoma Elli Maria Tiliakou, Michael Lizardo, Yue-Zhou Huang, Taras Shyp, Poul Sorensen

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