PO.TB10.05 · 肿瘤生物学
Aging and Host Determinants of Tumor Progression: The Macroenvironmental Axis
- 2071 2071 衰老损害NK细胞监视功能以促进乳腺癌转移性生长 Aging impairs NK-cell surveillance to promote metastatic outgrowth in breast cancer Pulkit Datt, Jhon Pasamonte, Kelly Coutant, Anastasiia Burtseva, Mitchell Fane
- 2072 2072 衰老对γδ T细胞在转移性皮肤黑色素瘤进展中的作用 Role of the aging on the ᵧdelta T-cells in metastatic cutaneous melanoma progression Kelly Coutant, Christopher Price, Jhon Pasamonte, Pulkit Datt, Mitchell Fane
-
- 2074 2074 腺苷驱动的衰老癌症相关成纤维细胞炎症性重编程促进胰腺导管腺癌中的免疫抑制 Adenosine-driven inflammatory reprogramming of aged cancer-associated fibroblasts promotes immune suppression in pancreatic ductal adenocarcinoma Shuncang Zhu, Jinpeng Lu, Ziyi Tu, Hongyi Lin, Yinhao Chen, Yiting Chen, Haoxiang Zhang, Zuwei Wang, Shi Chen
- 2075 2075 乳酸驱动的胆固醇重编程诱导衰老胰腺癌中的成纤维细胞衰老和免疫抑制 Lactate-driven cholesterol reprogramming induces fibroblast senescence and immune suppression in aged pancreatic cancer Ziyi Tu, Jinpeng Lu, Shuncang Zhu, Hong-yi Lin, Yi-ting Chen, Yinhao Chen, Haoxiang Zhang, Zu-Wei Wang, Shi Chen
-
-
- 2078 2078 衰老通过组织浸润性Treg促进肝和肺黑色素瘤转移 Aging promotes liver and lung melanoma metastasis via tissue-infiltrating Tregs Anastasiia Burtseva, Kelly Coutant, Jhon Pasamonte, Christopher Price, Mitchell Fane
-
- 2080 2080 衰老诱导的IL-11增加通过髓系细胞极化导致黑色素瘤中的免疫逃逸和PD-1抵抗 Aged-induced increases in IL-11 leads to immune escape and PD-1 resistance in melanoma through myeloid cell polarization Michael F. Emmons, Chao Zhang, ethan vallebuona, Richard L. Bennett, Manali Phadke, Jonathan D. Licht, Keiran Smalley
- 2081 2081 宿主年龄对早发或晚发西班牙裔结直肠癌患者来源肿瘤表观遗传学的影响 Age of host impact on epigenetics in tumors derived from early or late onset Hispanic colorectal cancer patients Lesly Torres-Gonzalez, Shivani Soni, Zeyi Yang, Ben Y. Tew, Jae H. Lo, Pooja Mittal, Unnati H. Shah, Michela Bartolini, Steve Soto Trujillo, Yitzher Goretsky, Sandra Algaze, Wu Zhang, David W. Craig, John D. Carpten, Salhia Bodour, Heinz-Josef Lenz
- 2082 2082 多重免疫荧光揭示卵巢癌中与年龄和免疫治疗反应相关的区室特异性免疫细胞相关性 Multiplex immunofluorescence reveals compartment-specific immune cell correlations associated with age and immunotherapy response in ovarian carcinoma Kathy Kwock, Okan Gültekin, Hanim I. Ozkizilkaya, Lynda D. Roman, William Dean Wallace, Tirzah Petta, Joseph W. Carlson
-
- 2084 2084 血管紧张素II诱导的慢性高血压重编程胰腺导管腺癌的抗肿瘤免疫反应 Angiotensin-II-induced chronic hypertension reprograms the antitumor-immune-response in pancreatic ductal adenocarcinoma Benjamin Wolf, Heena Kumra, Ryo Morisue, Karim El-marouk, Igor L. Gomes-Santos, Rieke Schleinhege, Tsion H. Tale, Marc Charabati, Sonu Subudhi, Dai Fukumura, Rakesh K. Jain
-
-
-
-
-
- 2091 2091 孕酮通过调节CD4 T细胞活力和辅助功能、促进T细胞凋亡以及从炎性向抗炎性细胞因子谱转变，促进小鼠乳腺肿瘤中的免疫抑制 Progesterone promotes immunosuppression in murine mammary tumors by modulating CD4 T cell viability and helper functions, promoting T cell apoptosis and a shift from inflammatory to anti-inflammatory cytokine profiles Amanda Glen Heard
- 2092 2092 单细胞RNA测序揭示非小细胞肺癌中与祖源相关的分子和细胞免疫抑制特征 Single-cell RNA sequencing reveals ancestry-associated molecular and cellular immunosuppressive features in non-small cell lung cancer Liang Liu, Pengbo Zhang, Enzo Palma, Ashley Ballard, Lance Miller, Gregory Hawkins, Cristina M. Furdui, Edward Levine, Alberto de Hoyos, Wencheng Li, Fang-Chi Hsu, Ralph D'Agostino, David Foureau, Wei Zhang
- 2093 2093 阐明西班牙裔/拉丁裔肺腺癌患者中EGFR突变发生率升高之间的机制联系 Elucidating the mechanistic connection between the elevated occurrence of EGFR mutation in Hispanic/Latinx lung adenocarcinoma patients Jonathan Castillo, William D. Wallace, Leonidas Arvanitis, Dan Raz, Crystal N. Marconett
- 2094 2094 研究遗传背景对TNBC类器官和共培养中TNBC-T细胞相互作用的影响 Investigating the influence of genetic background on TNBC-T cell interactions in TNBC organoids and co-cultures Batoul Farran, Moses Kamita, Shuk Mei Wong, Sylvester Antwi, Valerie Ofori Aboah, Harriet Larrious-Lartey, Jessica Jessica Bensenhaver, Ali Haythem, Walker Eleonor, Foster Amponsah, Josephine Nsafu., Rose Dampson, Patrick Kafui Akapko, Evelyn Jiage
-
-
-
-
-
