Spatial Proteomics and Transcriptomics 2

• 3950 3950 NMIBC进展的微环境驱动因素的空间转录组学解析 Spatial transcriptomic dissection of microenvironmental drivers of NMIBC progression Jacob Alltucker, Yiling Shen, Suhyeon Choi, Pavithra Nedumaran, Andrew Martinez, Joseph Lownik, Huihui Ye, Hideki Furuya, Dan Theodorescu, Simon Knott
• 3951 · PDF 初治胰腺癌中B7-H3介导的细胞可塑性的空间图谱绘制 Spatial mapping of B7-H3 mediated cellular plasticity in treatment naive pancreatic cancer Assya Legrini, Tengyu Zhang, Mari-Claire McGuigan, Colin Wood, Luke McNickle, Claire Kennedy-Dietrich, Ghazal Latifi, Yoana Doncheva, Josefina Vasquez, Hannah Morgan, Pamela McCall, Michail Doukas, Joanne Edwards, Nigel Jamieson
• 3952 · PDF 通过GlycoScope-IN-DEPTH对滤泡性淋巴瘤进行空间多组学解析，揭示galectin-8L驱动的补体富集、免疫耗竭的微环境 Spatial multi-omics dissection of follicular lymphoma by GlycoScope-IN-DEPTH reveals a galectin-8L-driven complement-enriched, immune-exhausted microenvironment Stephanie P. T. Yiu, Ankit Basak, Carolina Ortiz-Cordero, Alex K. Shalek, Laura Kiessling, Sizun Jiang
• 3953 · PDF 利用空间蛋白质组学评估免疫聚集体作为阑尾腺癌（AA）免疫治疗反应潜在生物标志物的作用 Assessing the role of immune aggregates as potential biomarkers of immunotherapy response in appendiceal adenocarcinoma (AA) using spatial proteomics Matt Lastrapes, Eleanor A. Fallon, Brenda Melendez, Bharat B. Singh, Davis Ingram, Khalida M. Wani, Lon W. Fong, Ashish Damania, Vivian Orellana, Nadim J. Ajami, Jillian Losh, Alexander Lazar, Kanwal Pratap Singh Raghav, John P. Shen, Melissa Taggart, Jennifer A. Wargo, Beth A. Helmink, Paul A. Scheet, Michael Geoffrey White
• 3954 · PDF 识别BRAF p.V600E突变型结直肠癌（mCRC）应答的生物标志物 Identifying biomarkers of response in BRAF p.V600E mutant colorectal cancers (mCRC) Gagandeep Brar, Brooke Rhead, Unnati Jariwala, Stamatina Fragkogianni, Amit Mahipal
• 3955 · PDF 利用基于注意力的建模对非裔美国结直肠癌患者中MMR-p与MMR-d肿瘤-免疫相互作用的空间表征 Spatial characterization of tumor-immune interactions in MMR-p and MMR-d among African American colorectal cancer patients using attention-based modeling Hassan Brim, Khushi Desai, Shweta Dixi, Justin Hong, Colles Price, Jonathan H. Chen, Nicolas Fernandez, Sara Sim, Sami Farhi, Rabia Zafar, Elham Azizi, Hassan Ashktorab
• 3956 · PDF ER阳性乳腺肿瘤的空间转录组图谱揭示抗PD-1治疗后的免疫通路重塑与耐药机制 Spatial transcriptomic mapping of ER-positive breast tumors reveals immune pathway remodeling and resistance mechanisms following anti-PD-1 therapy Oliver J. De Sa, Megan Hopkins, Angel Arnaout, Arif Awan, Gregory Pond, Jane Bayani, Melanie Spears
• 3957 · PDF 晚期胃癌中空间来源的转录组学免疫检查点阻断疗效预测因子 Spatially derived transcriptomic predictors of immune checkpoint blockade outcome in advance gastric cancer Changjin Hong, Sunho Park, Jean R. Clemenceau, Minji Kim, Inyeop Jang, Seock-Jin Chung, Sung Hak Lee, Sam C. Wang, Tae Hyun Hwang
• 3958 · PDF 腹膜转移的空间转录组学分析识别接受加压腹腔内气溶胶化疗（PIPAC）患者肿瘤中的多细胞程序 Spatial transcriptomic profiling of peritoneal metastases identifies multicellular programs in patient tumors undergoing pressurized intraperitoneal aerosol chemotherapy (PIPAC) Heini Maaret Natri, Arianna L. Williams-Katek, Muhammad Talha Waheed, Tiana Li, Marwan Fakih, Mingye Feng, Amit Merchea, Sue Chang, Richard L. Whelan, Danielle Deperalta, Thanh H. Dellinger, Nicholas Banovich, Mustafa Raoof
• 3959 · PDF 利用空间多组学探索胶质瘤恶性转化的新方法 Novel methodology to explore glioma malignant transformation with spatial multi-omics Michal Polonsky, Jonathan Fox, Sheel Shah, Noa Hadas, Richard Everson, Long Cai
• 3960 · PDF 胆囊癌从前驱阶段到未分化阶段的空间分辨转录组学特征 Spatially resolved transcriptomic signatures of gallbladder carcinogenesis from precursor to undifferentiated stages Yeseul Kim, Yoseob Lee, Harim Oh, You-Na Sung, Yoo Jin Lee, Yona Kim, Inho Park, Jinhyuk Bhin, Su-Jin Shin
• 3961 · PDF 识别胶质母细胞瘤浸润边缘细胞的分子特征作为肿瘤侵袭和复发的驱动因素 Identifying the molecular signature of infiltrating edge cells in glioblastoma as drivers of tumour invasion and recurrence Alyona Ivanova, Shamini Ayyadhury, Yanxia Ma, Xuehong Gui, Akshay V. Basi, Megan Yijun Wu, Trevor J. Pugh, David G. Munoz, Sungnam Cho, Tosin Oyewale, Lucas Schütz, Chibawanye I. Ene, Jared K. Burks, Sunit Das
• 3962 · PDF 利用 HCR™ Gold IF 实现同种属多重免疫荧光：使用 Abcam 经肿瘤学验证的一抗进行跨克隆基准评估 Same-species multiplex IF with HCR™Gold IF: Cross-clone benchmarking using Abcam's oncology-validated primaries Wudy Yang, Randy Chen, Harry Choi, Aneesh Acharya, Will Howat
• 3963 · PDF 空间分辨的细胞间通讯揭示小细胞肺癌的瘤内异质性 Spatially Resolved Cell-Cell Communication Reveals Intra-tumoral heterogeneity in Small Cell Lung Cancer Tingxiao Gao, Jalal Kazan, Fatema Zohora, Gregory Schwartz, Benjamin Lok
• 3964 · PDF 利用 seqFISH 对神经母细胞瘤肿瘤微环境进行空间刻画 Spatial profiling of the neuroblastoma tumor microenvironment using seqFISH Christopher Riccardi, Michal Polonsky, Michael J. Zobel, Rebekah Kennedy, Melody Khoshneviszadeh, Anya Zdanowicz, Bruce Pawel, James Amatruda, Long Cai, Shahab Asgharzadeh
• 3965 · PDF 癌组织中神经内分泌参与的空间组学检测 Spatialomics detection of neuroendocrine involvement in cancer tissue Scott T. Clarke, Chris Vonnegut, Leticia Montoya, Mae Voeun, Wenjun Zhou, Anna Cartier, Aleksey Rukavishnikov
• 3966 · PDF 利用 CosMx 空间分子成像仪对乳腺癌组织进行原位空间多组学刻画 In situ spatial multiomic profiling of breast cancer tissue utilizing the CosMx Spatial Molecular Imager Megan Hopkins, Oliver De Sa, Dan Dion, Vida Talebian, Jane Bayani, Melanie Spears
• 3967 · PDF 利用 CosMx 空间分子成像仪对乳腺癌组织进行空间全转录组刻画 Spatial whole transcriptomic profiling of breast cancer tissue with CosMx Spatial Molecular Imager Megan Hopkins, Oliver De Sa, Dan Dion, Vida Talebian, Jane Bayani, Melanie Spears
• 3968 · PDF 三阴性乳腺癌中与新辅助治疗反应相关的空间转录组特征 Spatial transcriptomic features associated with response to neoadjuvant therapy in triple-negative breast cancer Shiqing Liao, Teia Noel, Joseph Lownik, Pavithra Nedumaran, Yoona Yang, Richard Mebane, Aagam Shah, Andrew Martinez, Akil A. Merchant, Simon Knott
• 3969 3969 Stereo-seq 空间转录组学揭示细胞类型对前列腺癌转移的贡献 Stereoseq spatial transcriptomics reveals cell-type contributions to prostate cancer metastasis Jonathan Panzer, Shannon Carskadon, Albert Levin, Sean Huang, Vikrant Kumar, Indra Adrianto, Nallasivam Palanisamy
• 3970 · PDF 使用 FusionPlus Hi-C 对存档的卵巢和子宫癌肉瘤 FFPE 组织进行全基因组检测以确定 HRD 状态 Genome wide testing of archived ovarian and uterine carcinosarcoma FFPE tissue using FusionPlus Hi-C to determine HRD status Amanda Bradshaw, Christopher Elms, Mia Jeffris, Jon Belton, Williams Ricketts, Alex R. Hastie, Michael Birrer
• 3971 · PDF 使用 Ultivue InSituPlex 与无蛋白酶 RNAscope 混合工作流对实体瘤中抗体药物偶联物标志物和 RNA 生物标志物进行快速检测 Rapid antibody drug conjugate markers and RNA biomarkers in solid tumors using a hybrid Ultivue InSituPlex and Protease-Free RNAscope Workflow Patrick Savickas, AKASH PARVATIKAR, Jack Casey, Anushka Dikshit, AMAN TYAGI
• 3972 · PDF 在临床试验中使用 17 重免疫荧光检测对实体瘤进行全面的免疫图谱分析 Comprehensive immune landscape analysis of solid tumors using a 17-Plex immunofluorescence assay in clinical trials Jaspreet Kaur, Richard Van Krieken, Xun Li, Ying Huang, Lisa Kattenhorn, Naveen Dakappagari, Margaret E. McLaughlin, Jennifer Bordeaux
• 3973 · PDF 使用 CellScape 平台通过空间蛋白质-转录组学进行抗体验证的框架 A framework for antibody validation via spatial proteo-transcriptomics using the CellScape platform Tim Schunk, Tim Mandelkow, Shida Xiong, Jonas Raedler, Rodler Severin, Philipp Nuhn, Anne Letsch, Marion van Macklenbergh, Jan Weitkamp, Jakob Kohler, Arne Christians, Oliver Braubach, Steve Lott, Micaela Mathiak, Gavin Gordon, Björn Konukiewitz, Christoph Rocken, Niclas Christian Blessin
• 3974 · PDF 通过单细胞全转录组成像解码浸润性导管癌中的癌症标志 Decoding cancer hallmarks through single-cell whole transcriptome imaging in invasive ductal carcinoma Claire Williams, Patrick Danaher, Megan Vandenberg, Martin Shelton, Mirko Corselli, Christine Kang, John Lyssand, Joseph Beechem
• 3975 · PDF 空间分辨多组学揭示 HGSOC 中转移性生态系统重塑和免疫调节生态位 Spatially resolved multi-omics reveal metastatic ecosystem remodeling and immunomodulatory niches in HGSOC Yufeng He, Ce Luo, Yuanguang Meng, Zhe Zhang, Zexian Zeng

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