Immune Mechanisms Invoked by Other Therapies and Exposures

• 2828 2828 紫杉醇诱导CXCL9+肿瘤相关巨噬细胞与CD8+ T细胞共定位以增强头颈部鳞状细胞癌的抗肿瘤免疫 Paclitaxel induces colocalization of CXCL9⁺ tumor-associated macrophages and CD8⁺ T cells to potentiate antitumor immunity in head and neck squamous cell carcinoma Minsu Kwon, Jeong Heon Kim, Jisu Hong, Seo-Won Choi, Jung Min Kim, Hyo Jung Cho, Myungchan Park, JI-HYUN SEO, Jung Je Park
• 2829 · PDF Afatinib对T细胞介导的细胞毒性发挥抑制作用 Afatinib exerts an inhibitory effect on T cell-mediated cytotoxicity Masaru Yokomura, Seiji Nagano, Hiroshi Kawamoto, Takahiro Asakage, Ryohei Katayama
• 2830 · PDF Dato-DXd处理的非小细胞肺癌患者来源类器官型肿瘤球(pDOTS)中的免疫调节反应 Immunomodulatory response in Dato-DXd-treated non-small cell lung cancer patient-derived organotypic tumor spheroids (pDOTS) Satoru Yasuda, Patrick Hall Lizotte, Elena Ivanova, Zhaorong Li, Yui Tanaka, Daisuke Okajima, Minh Ha, David A. Barbie, Cloud P. Paweletz
• 2831 · PDF daraxonrasib对癌细胞和免疫细胞中RAS(ON)的双重抑制驱动抗肿瘤免疫 RAS(ON) inhibition in both cancer and immune cells by daraxonrasib drives anti-tumor immunity Nataliya Tovbis Shifrin, Mariela Moreno Ayala, Cristina Blaj, Kevin Chen, Felix Mbuga, Joaquin Pechuan Jorge, Rashi Raghulan, Rich Liang, Linh Tran, Enrico Payson, Alice Kumamoto, Alexander McNamara, Marie Josette Catherine Menard, Michael Weiss, Lillian Seu, Elsa Quintana
• 2832 2832 评估自然杀伤细胞对乳腺癌患者来源异种移植衍生3D模型中Enhertu毒性的贡献 Evaluation of Natural Killer cells' contribution to Enhertu toxicity in breast cancer patient derived xenograft-derived 3D models Chou Fu-Ju, Annamaria Rapisarda, Veena Jagannathan, Marianna Zipeto, Michael Ritchie, Markus Hippich, Daniel Ciznadija, Brandon Walling, Stefano Cairo, Mara Gilardi, BanuPriya Sridharan
• 2833 · PDF Amivantamab通过EGFR/MET表达依赖性机制在非小细胞肺癌中恢复抗肿瘤免疫 Amivantamab restores antitumor immunity in non-small cell lung cancer through EGFR/MET expression-dependent mechanisms Takamasa Ishino, Ryo Yoshichika, Fumiaki Mukohara, Ken Suzawa, Shinichi Toyooka, Yosuke Togashi
• 2834 · PDF 鉴定CXCL10-CXCR3轴为弥漫性中线胶质瘤(DMG)放疗耐受的介导因素 Identification of CXCL10-CXCR3 axes as mediators of radioresistance in diffuse midline glioma (DMG) Mostafa M. H. Ibrahim, Niloofar Khairkhah, Carl Koschmann, Yue Zhao, Stefanie Galban
• 2835 · PDF 利用放射诱导的表面蛋白靶点重编程肿瘤微环境 Leveraging radiation inducible surface protein targets for tumor microenvironment reprogramming Courtney M. Tamaki, Maxwell Foisey, Charlotte Chen, Nam Woo Cho
• 2836 2836 肿瘤来源的细胞外囊泡作为放疗诱导免疫原性细胞死亡的关键信使,使小细胞肺癌对免疫治疗敏感 Tumor-derived extracellular vesicles as key messengers of radiotherapy-induced immunogenic cell death to sensitize small cell lung cancer to immunotherapy Shanghai Liu, Kai Kang, Zhuoran Yao, Ren Luo, Hui Wang, Zichong Peng, Shuangsi Liao, Yilan Zeng, Ruizhan Tong, Jiaming Zeng, Weidi Xiao, Jianxin Xue, Linglu Yi, Chu Wang, You Lu
• 2837 · PDF 碳离子放射治疗后肿瘤免疫细胞浸润和抗原提呈增强与治愈性疗效相关 Enhanced tumor immune cell infiltration and antigen presentation after carbon ion radiotherapy correlates with curative outcomes Matilde Recusani, Sarah Meister, Federica Ciamarone, Julian Schlegel, Ralph Sinn, Carmen Klein, Jennifer Furkel, Aoife Gahlawat, Christel Herold-Mende, Max Knoll, Michael Breckwoldt, Dirk Jaeger, Juergen Debus, Amir Abdollahi
• 2839 · PDF 抑制两种IIb类HDAC优于同工型特异性抑制，可改善抗肿瘤免疫应答 Inhibiting both Class IIb HDACs is superior to isoform-specific inhibition for improved antitumor immune response. Satish Kumar Reddy Noonepalle, Manasa Suresh, Xintang Li, Sonia Sebaoui, Bryan Weselman, Marie Durr, Nithya Gajendran, Chiara Ripamonti, Gianluca Fossati, Christian Steinkuhler, Alejandro Villagra
• 2840 · PDF 利用5-氟尿嘧啶调节肿瘤微环境以增加乳腺癌骨转移中的T细胞浸润 Modulation of the tumor microenvironment using 5-fluorouracil to increase T cell infiltration in breast cancer bone metastases Galilea Chora Hernández, Paloma Almeida Luna, Kiomy Esparza Palomares, Erasmo Pérez Mendez, Samanta Jimenez, Ricardo Gonzalez Sanchez, Candice Internicola, Felipe Olvera, Pierrick G.J. Fournier
• 2841 · PDF PM54重塑肿瘤微环境以增强检查点阻断疗效 PM54 reshapes the tumor microenvironment to potentiate checkpoint blockade Eugenio Bustos-Morán, Daniel Torralba, Ismael Fernández-Miranda, Maria José Guillen, Pablo Avilés, Marcelo L. Ribeiro, Carmen Cuevas
• 2842 · PDF 探讨二甲双胍提高溶瘤疱疹病毒在卵巢癌中疗效的能力 Investigating the capability of metformin to increase the efficacy of oncolytic herpesvirus in ovarian cancer Emma Sielski, Maria C. Courreges, Fabian Benencia
• 2843 2843 高级别浆液性卵巢癌铂类化疗后肿瘤微环境中MAVS表达和T细胞浸润的变化 Changes in MAVS expression and T-cell infiltration in the tumor microenvironment following platinum-based chemotherapy in high-grade serous ovarian carcinoma Yuki Yasui, Erika Nakatsuka, Yusaku Shimizu, Mina Sakata, Yuki Takemoto, Gaku Yamamoto, Aasa Shimizu, Mahiru Kawano, Yasuto Kinose, Kenjiro Sawada, Michiko Kodama
• 2844 · PDF 大麻吸食增加全身炎症并降低免疫力 Cannabis smoking increases systemic inflammation and reduces immunity Adele Hammoudi, Mayilvanan Chinnaiyan, Sulfath Thottungal Parambil, Gautham Chengizkhan, Vengatesh Ganapathy, Lurdes Queimado
• 2845 2845 人血清蛋白质组学揭示电子烟使用者中细胞外囊泡介导的代谢-黏附信号传导及适应性免疫抑制 Human serum proteomics reveals extracellular vesicle-mediated metabolic-adhesive signaling and suppression of adaptive immunity in E-cigarette users Rizwana Begum, Shilpa Thota, Shreya Pokharel, Biplov Sapkota, Joseph Francis
• 2846 · PDF HIV感染者中与牙周病及口腔癌风险相关的炎症小体依赖性和非依赖性失调 Inflammasome dependent and independent dysregulation associated with periodontal disease and oral cancer risk in people with HIV Alejandro Yamil Odeh, Juliana Mary Serrano-Rodriguez, Jurelis Torres Reyes, Oscar Antonio Loperena Gonzalez, Jeannette L. Salgado Montilla, Ramon F. Gonzalez-Garcia, Gabriel Borges Velez, Josue Perez-Santiago
• 2847 · PDF 甜蜜助推：三氯蔗糖在体外增强调节性T细胞（Treg）功能 Sweet boost: Sucralose enhances regulatory T cell (Treg) functions in vitro Sadhana Bom, Jessica A. Jana, Kelsey M. Ertwine, Rachel Cumberland, Kristin T. Morder, Abigail E. Overacre-Delgoffe
• 2848 · PDF 利用SHP2靶向信号传导以强化抗肿瘤免疫应答 Harnessing SHP2-targeted signaling to reinforce anti-tumor immune responses Bayarbat Tsevegjav, Hirotake Tsukamoto, Osamu Kikuchi
• 2849 · PDF 内皮抑素与催乳素联合触发PRLR诱导并在TNBC中引导CD1d信号传导 Endostatin and prolactin combination trigger PRLR induction and channelize CD1d signaling in TNBC Ritis Kumar Shyanti, Rajesh Singh, Manoj K. Mishra
• 2850 · PDF PHI-501，一种新型泛RAF抑制剂，通过将冷肿瘤转化为热肿瘤增强免疫治疗疗效 PHI-501, a novel pan-RAF inhibitor, enhances immunotherapy efficacy by converting cold tumors into hot tumors Sung Eun Kim, Sue Min Kim, Ky-Youb Nam, JeongHyeok Yoon, Sang Joon Shin
• 2851 · PDF EGFR-TKI驱动非小细胞肺癌中CD8⁺ T细胞免疫的重编程 EGFR-TKI drives the reprogramming of CD8⁺ T cell immunity in non-small cell lung cancer Ssu-Pei Yu, Hao-Chen Chi, Meng-Yun Lin, Chao-Chi Ho, Geen-Dong Chang, Ming-Shyue Lee, Chun-Jung Ko
• 2852 2852 利用新型腺相关病毒介导疗法靶向三阴性乳腺癌中的Notch信号传导以增强免疫调节 Targeting notch signaling in triple negative breast cancer with a novel adeno-associated virus-mediated therapy to enhance immunomodulation Mrityunjoy Biswas, Md. Manirujjaman, Yong Ran, Samarpan Majumder, Luis Del Valle, Jovanny Zabaleta, Barbara A. Osborne, Lucio Miele, Todd Golde, Fokhrul Hossain
• 2853 · PDF VPAC拮抗作为前列腺癌的潜在治疗手段 VPAC antagonism as potential therapeutic for prostate cancer YuJie Chen, Tuisha Gupta, Kiranj Chaudagar, Edmund K. Waller
• 2854 · PDF 抗生素削弱HER2+乳腺癌治疗疗效背后的固有免疫机制 Antibiotics blunt the innate immune mechanisms underlying HER2+ breast cancer therapy efficacy Lily J. Parker, Payal Mitra, Nofar Erlichman, Pavani Chalasani, Rong Li, Romina E. Araya
• 2855 · PDF ²¹²Pb-PSMA放射性配体治疗在免疫功能正常前列腺癌模型中的评估 Evaluation of ²¹²Pb-PSMA radioligand therapy in an immunocompetent prostate cancer model Melissa Monterosso, Aneesha Jones, Kayden Kwah, Anna Amiss, Didier Boucher, Aimee Horsfall, Heather Green, Johannes Koehbach, Ralph Huebner, Yaowu He, Stephen Rose, Gary Li, Feifei Liu, Joana Brilhante, Simon Puttick, Anna Karmann, John Hooper, Thomas Kryza
• 2856 · PDF 通过抑制拓扑异构酶I诱导免疫原性细胞应激 Induction of immunogenic cell stress through the inhibition of topoisomerase I Douglas E. Kline, Cory Alvey, Adelyn L. Zelaya Lazo, Tanushree Samanta, Amy Neely, Alireza Tafazzol, James Grayczyk, Luke Broses, Erik Ladomersky, Julie Purkal, Ji Huang, Greg Buchanan, Kenneth Bromberg, Relja Popovic, Darren Phillips
• 2857 2857 反复RFA重塑PDAC微环境并与CSF1R阻断和检查点抑制协同增强抗肿瘤免疫 Repeated RFA remodels the PDAC microenvironment and synergizes with CSF1R blockade and checkpoint inhibition to enhance anti-tumor immunity Lincoln Strickland, Wendao Liu, Casey Van Kirk, Shwetapadma Dash, MacKenzie Demmel, Alyssa Waller, Nicolette R. Mardik, Jesse Cox, Curtis J. Wray, Zhongming Zhao, Nirav Thosani, Jennifer Bailey-Lundberg

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