Immune Mechanisms Invoked by Other Therapies and Exposures

• 2828 2828 Paclitaxel induces colocalization of CXCL9⁺ tumor-associated macrophages and CD8⁺ T cells to potentiate antitumor immunity in head and neck squamous cell carcinoma Minsu Kwon, Jeong Heon Kim, Jisu Hong, Seo-Won Choi, Jung Min Kim, Hyo Jung Cho, Myungchan Park, JI-HYUN SEO, Jung Je Park
• 2829 · PDF Afatinib exerts an inhibitory effect on T cell-mediated cytotoxicity Masaru Yokomura, Seiji Nagano, Hiroshi Kawamoto, Takahiro Asakage, Ryohei Katayama
• 2830 · PDF Immunomodulatory response in Dato-DXd-treated non-small cell lung cancer patient-derived organotypic tumor spheroids (pDOTS) Satoru Yasuda, Patrick Hall Lizotte, Elena Ivanova, Zhaorong Li, Yui Tanaka, Daisuke Okajima, Minh Ha, David A. Barbie, Cloud P. Paweletz
• 2831 · PDF RAS(ON) inhibition in both cancer and immune cells by daraxonrasib drives anti-tumor immunity Nataliya Tovbis Shifrin, Mariela Moreno Ayala, Cristina Blaj, Kevin Chen, Felix Mbuga, Joaquin Pechuan Jorge, Rashi Raghulan, Rich Liang, Linh Tran, Enrico Payson, Alice Kumamoto, Alexander McNamara, Marie Josette Catherine Menard, Michael Weiss, Lillian Seu, Elsa Quintana
• 2832 2832 Evaluation of Natural Killer cells' contribution to Enhertu toxicity in breast cancer patient derived xenograft-derived 3D models Chou Fu-Ju, Annamaria Rapisarda, Veena Jagannathan, Marianna Zipeto, Michael Ritchie, Markus Hippich, Daniel Ciznadija, Brandon Walling, Stefano Cairo, Mara Gilardi, BanuPriya Sridharan
• 2833 · PDF Amivantamab restores antitumor immunity in non-small cell lung cancer through EGFR/MET expression-dependent mechanisms Takamasa Ishino, Ryo Yoshichika, Fumiaki Mukohara, Ken Suzawa, Shinichi Toyooka, Yosuke Togashi
• 2834 · PDF Identification of CXCL10-CXCR3 axes as mediators of radioresistance in diffuse midline glioma (DMG) Mostafa M. H. Ibrahim, Niloofar Khairkhah, Carl Koschmann, Yue Zhao, Stefanie Galban
• 2835 · PDF Leveraging radiation inducible surface protein targets for tumor microenvironment reprogramming Courtney M. Tamaki, Maxwell Foisey, Charlotte Chen, Nam Woo Cho
• 2836 2836 Tumor-derived extracellular vesicles as key messengers of radiotherapy-induced immunogenic cell death to sensitize small cell lung cancer to immunotherapy Shanghai Liu, Kai Kang, Zhuoran Yao, Ren Luo, Hui Wang, Zichong Peng, Shuangsi Liao, Yilan Zeng, Ruizhan Tong, Jiaming Zeng, Weidi Xiao, Jianxin Xue, Linglu Yi, Chu Wang, You Lu
• 2837 · PDF Enhanced tumor immune cell infiltration and antigen presentation after carbon ion radiotherapy correlates with curative outcomes Matilde Recusani, Sarah Meister, Federica Ciamarone, Julian Schlegel, Ralph Sinn, Carmen Klein, Jennifer Furkel, Aoife Gahlawat, Christel Herold-Mende, Max Knoll, Michael Breckwoldt, Dirk Jaeger, Juergen Debus, Amir Abdollahi
• 2839 · PDF Inhibiting both Class IIb HDACs is superior to isoform-specific inhibition for improved antitumor immune response. Satish Kumar Reddy Noonepalle, Manasa Suresh, Xintang Li, Sonia Sebaoui, Bryan Weselman, Marie Durr, Nithya Gajendran, Chiara Ripamonti, Gianluca Fossati, Christian Steinkuhler, Alejandro Villagra
• 2840 · PDF Modulation of the tumor microenvironment using 5-fluorouracil to increase T cell infiltration in breast cancer bone metastases Galilea Chora Hernández, Paloma Almeida Luna, Kiomy Esparza Palomares, Erasmo Pérez Mendez, Samanta Jimenez, Ricardo Gonzalez Sanchez, Candice Internicola, Felipe Olvera, Pierrick G.J. Fournier
• 2841 · PDF PM54 reshapes the tumor microenvironment to potentiate checkpoint blockade Eugenio Bustos-Morán, Daniel Torralba, Ismael Fernández-Miranda, Maria José Guillen, Pablo Avilés, Marcelo L. Ribeiro, Carmen Cuevas
• 2842 · PDF Investigating the capability of metformin to increase the efficacy of oncolytic herpesvirus in ovarian cancer Emma Sielski, Maria C. Courreges, Fabian Benencia
• 2843 2843 Changes in MAVS expression and T-cell infiltration in the tumor microenvironment following platinum-based chemotherapy in high-grade serous ovarian carcinoma Yuki Yasui, Erika Nakatsuka, Yusaku Shimizu, Mina Sakata, Yuki Takemoto, Gaku Yamamoto, Aasa Shimizu, Mahiru Kawano, Yasuto Kinose, Kenjiro Sawada, Michiko Kodama
• 2844 · PDF Cannabis smoking increases systemic inflammation and reduces immunity Adele Hammoudi, Mayilvanan Chinnaiyan, Sulfath Thottungal Parambil, Gautham Chengizkhan, Vengatesh Ganapathy, Lurdes Queimado
• 2845 2845 Human serum proteomics reveals extracellular vesicle-mediated metabolic-adhesive signaling and suppression of adaptive immunity in E-cigarette users Rizwana Begum, Shilpa Thota, Shreya Pokharel, Biplov Sapkota, Joseph Francis
• 2846 · PDF Inflammasome dependent and independent dysregulation associated with periodontal disease and oral cancer risk in people with HIV Alejandro Yamil Odeh, Juliana Mary Serrano-Rodriguez, Jurelis Torres Reyes, Oscar Antonio Loperena Gonzalez, Jeannette L. Salgado Montilla, Ramon F. Gonzalez-Garcia, Gabriel Borges Velez, Josue Perez-Santiago
• 2847 · PDF Sweet boost: Sucralose enhances regulatory T cell (Treg) functions in vitro Sadhana Bom, Jessica A. Jana, Kelsey M. Ertwine, Rachel Cumberland, Kristin T. Morder, Abigail E. Overacre-Delgoffe
• 2848 · PDF Harnessing SHP2-targeted signaling to reinforce anti-tumor immune responses Bayarbat Tsevegjav, Hirotake Tsukamoto, Osamu Kikuchi
• 2849 · PDF Endostatin and prolactin combination trigger PRLR induction and channelize CD1d signaling in TNBC Ritis Kumar Shyanti, Rajesh Singh, Manoj K. Mishra
• 2850 · PDF PHI-501, a novel pan-RAF inhibitor, enhances immunotherapy efficacy by converting cold tumors into hot tumors Sung Eun Kim, Sue Min Kim, Ky-Youb Nam, JeongHyeok Yoon, Sang Joon Shin
• 2851 · PDF EGFR-TKI drives the reprogramming of CD8⁺ T cell immunity in non-small cell lung cancer Ssu-Pei Yu, Hao-Chen Chi, Meng-Yun Lin, Chao-Chi Ho, Geen-Dong Chang, Ming-Shyue Lee, Chun-Jung Ko
• 2852 2852 Targeting notch signaling in triple negative breast cancer with a novel adeno-associated virus-mediated therapy to enhance immunomodulation Mrityunjoy Biswas, Md. Manirujjaman, Yong Ran, Samarpan Majumder, Luis Del Valle, Jovanny Zabaleta, Barbara A. Osborne, Lucio Miele, Todd Golde, Fokhrul Hossain
• 2853 · PDF VPAC antagonism as potential therapeutic for prostate cancer YuJie Chen, Tuisha Gupta, Kiranj Chaudagar, Edmund K. Waller
• 2854 · PDF Antibiotics blunt the innate immune mechanisms underlying HER2+ breast cancer therapy efficacy Lily J. Parker, Payal Mitra, Nofar Erlichman, Pavani Chalasani, Rong Li, Romina E. Araya
• 2855 · PDF Evaluation of ²¹²Pb-PSMA radioligand therapy in an immunocompetent prostate cancer model Melissa Monterosso, Aneesha Jones, Kayden Kwah, Anna Amiss, Didier Boucher, Aimee Horsfall, Heather Green, Johannes Koehbach, Ralph Huebner, Yaowu He, Stephen Rose, Gary Li, Feifei Liu, Joana Brilhante, Simon Puttick, Anna Karmann, John Hooper, Thomas Kryza
• 2856 · PDF Induction of immunogenic cell stress through the inhibition of topoisomerase I Douglas E. Kline, Cory Alvey, Adelyn L. Zelaya Lazo, Tanushree Samanta, Amy Neely, Alireza Tafazzol, James Grayczyk, Luke Broses, Erik Ladomersky, Julie Purkal, Ji Huang, Greg Buchanan, Kenneth Bromberg, Relja Popovic, Darren Phillips
• 2857 2857 Repeated RFA remodels the PDAC microenvironment and synergizes with CSF1R blockade and checkpoint inhibition to enhance anti-tumor immunity Lincoln Strickland, Wendao Liu, Casey Van Kirk, Shwetapadma Dash, MacKenzie Demmel, Alyssa Waller, Nicolette R. Mardik, Jesse Cox, Curtis J. Wray, Zhongming Zhao, Nirav Thosani, Jennifer Bailey-Lundberg

在会议检索中浏览本分会场