Epigenomics

• 3219 · PDF Arid1a 指导乳腺上皮细胞的谱系定向 Arid1a directs lineage specification in mammary epithelial cells Erik Ladewig, Amaia Arruabarrena-Aristorena, Estelle Deby, Srushti Kittane, Fresia Pareja, Ryan Blawski, Yangzhenyu Gao, Laura Baldino, Vito Rebecca, Emiliano Cocco, Hongkai Ji, Pau Castel, Christina Leslie, Wouter Karthaus, Eneda Toska
• 3220 · PDF 整合表观基因组图谱分析揭示驱动雌激素受体阳性转移性乳腺癌治疗耐药的独特转录因子网络 Integrated epigenomic profiling reveals distinct transcription factor networks driving therapy resistance in estrogen receptor positive metastatic breast cancer Gizem Yayli-Vokshi, Sandra Cohen, Weiling Li, Hong Shao, Sydney Bowker, Elisa de Stanchina, Pedram Razavi, Sarat Chandarlapaty, Ekta Khurana
• 3221 · PDF 单细胞水平组蛋白修饰图谱分析以深入了解表观遗传药物治疗对肿瘤细胞的影响 Profiling histone modifications in single cells to gain insight into the effects of epigenetic drug treatment on tumor cells Shuwen Chen, Lisa Welter, Gilma Sevilla, Ploy Setthasap, Yana Ryan, Shiyi Yin, Alan Du, Jackson Peterson, Mike Covington, Mohammad Fallahi, Kazuo Tori, Bryan Bell, Bria Graham, Matt J. Meiners, Andrea L. Johnstone, Keith E. Maier, Martis W. Cowles, Bryan J. Venters, Michael Keogh, Xuan Qu, Colin McCornack, Ting Wang, Yue Yun, Andrew Farmer
• 3222 3222 采用多组学方法为沙特多形性胶质母细胞瘤识别新型生物标志物 Identifying novel biomarkers for Saudi glioblastoma multiform using multi-omics approach Abdulmonem A. Alsaleh, Ahmed Aloraidi, Bahauddeen M. Alrfaei
• 3223 · PDF 从福尔马林固定石蜡包埋样本进行染色质图谱分析以发现生物标志物 Chromatin profiling from formalin-fixed paraffin-embedded samples for biomarker discovery Andrea Lynn Johnstone, Eva Brill, Vishnu U. Kumary, Morgan Oatley, Martis W. Cowles, Michael-Christopher Keogh, Bryan J. Venters
• 3224 · PDF PIWIL4-piRNA相互作用的缺失揭示不确定的体细胞表观基因组演化 Loss of PIWIL4-piRNA interaction reveals uncertain somatic epigenomic evolution Yu-Wei Leu, Shu-Huei Hsiao
• 3225 · PDF 利用用于染色质状态和遗传变异的新型多组学长读长测序工具解析基因组调控复杂性 Resolving genome regulatory complexity with new multiomic long-read sequencing tools for chromatin state and genetic variation Lu Sun, James T. Anderson, Connor P. Frasier, Allison R. Hickman, Sabrina R. Hunt, Emily A. Madden, Keith E. Maier, Andrea L. Johnstone, Zu-Wen Sun, Martis W. Cowles, Andrew B. Stergachis, Bryan J. Venters, Michael-Christopher Keogh
• 3226 · PDF FOXA1改变通过乳腺癌中独特的转录和表观基因组程序驱动内分泌治疗耐药 FOXA1 alterations drive endocrine therapy resistance through unique transcriptional and epigenomic programs in breast cancer Srushti Kittane, Subhiksha Nandakumar, Enrico Moiso, Walid Khaled Chatila, Yangzhenyu Gao, Elza C. de Bruin, Claudette Falato, Ji Li, Hongkai Ji, Nikolaus Schultz, Maurizio Scaltriti, Pedram Razavi, Eneda Toska
• 3227 · PDF 定义肺癌中的神经分子特征及其功能意义 Defining neural molecular features and their functional significance in lung cancer Reshmee Bhattacharya, Daphni van Rinsum, Anna Dykhno, Hideo Watanabe
• 3228 · PDF NF-PanNETs的空间表观基因组图谱定义肿瘤进展及微环境生态位 Spatial epigenomic landscape of NF-PanNETs defines tumor progression and microenvironmental niches Yang Liu, Dejiang Wang, Xiangjun Di, Jing Du
• 3229 3229 染色质重塑因子SMARCA5在非裔美国人前列腺癌中表现出祖源特异性功能 The chromatin remodeler SMARCA5 displays ancestry-specific functions in African American prostate cancer Shahid Hussain, Khalid Mir, Sajad A. Wani, Solomon Rotimi, Lara Sucheston-Campbell, Clayton C. Yates, Moray J. Campbell
• 3230 · PDF BAP1缺失驱动葡萄膜黑色素瘤的表观基因组重编程 Epigenomic rewiring driven by BAP1 loss in uveal melanoma Gulum Yenisehirli, Aristeidis G. Telonis, Renata L. Volonterio, Monica Lopez, Jeffim N. Kuznetsoff, Ashley N. Zuniga, J. William Harbour, Zelia M. Correa, Stefan Kurtenbach
• 3231 · PDF 染色质谱分析揭示氟维司群对乳腺癌细胞中雌激素受体驱动的染色质动态的影响 Chromatin profiling reveals the impact of fulvestrant on estrogen receptor-driven chromatin dynamics in breast cancer cells Celine Barlier, Mathias Simplicien, Ana Hermoso, Anais Pourrat, Elsa Moreau, Celia Fontana, Aurelia Delherme, Natalie Daluege, Gurpreet Bharaj, Cibele de Oliveira, Alexander Vogt, Vincent Piras, Coralie Hoareau-Aveilla, Francisco Cruzalegui, Gaylor Boulay, Isabel Paiva
• 3232 · PDF NOP16是一种组蛋白拟态蛋白,调控组蛋白H3K27甲基化和基因抑制 NOP16 is a histone mimetic that regulates histone H3K27 methylation and gene repression Aamir Khan*, Ken Takashima*, Dian-Jang Lee, María Fernanda Trovero, Xing Wang, M. Hafiz Rothi, Ying Zhang, Zilan Li, Sarah Niesen, Julia Natale, Ernst Schmid, Joseph Al Haddad, Sabine Dietmann, Sumio Ohtsuki, Shannan Ho Sui, Hiroyuki Oshiumi, Judy Lieberman, Eric Lieberman Greer

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