Tumorigenesis Drivers

• 3326 · PDF 早发性结直肠癌（EOCRC）中由分化因子驱动的C-myc C-myc driven by differentiation factors in early-onset colorectal cancer (EOCRC) Kazuaki Okamoto, Yalda Naeini, Anton Bilchik, Dave Hoon
• 3327 · PDF L-MYC N端的结构和功能影响抑制MYC家族癌蛋白的策略 Structure and function of the L-MYC N-terminus impacts strategies to inhibit the MYC family of oncoproteins Tristan M. Kenney, Scott Houliston, Peter Chien-feng Lin, Nikan Movahedi, Cheryl Arrowsmith, Linda Z. Penn
• 3328 · PDF 探究结直肠癌细胞系对beta-catenin降解的耐药机制 Investigating resistance to beta-catenin degradation in a colorectal cancer cell line Reiss Clifford, Christopher I. Milton, Jasjot Singh, Marc Krenkel, Pradeep Ramagiri, Konstantinos Mitsopoulos, Frank Fischer, Marissa V. Powers, Dirk Wienke, Paul A. Clarke
• 3330 · PDF ccRCC肿瘤起始的空间与分子特征分析 Spatial and molecular profiling of tumor initiation in ccRCC Omar Bouricha, Daqi Deng, Anne-Laure Cattin, Matous Elphick, Scott Shepherd, Cathy D. Vocke, W. Marston Linehan, Samra Turajlic
• 3331 · PDF NanoGlio重现IDH突变型胶质瘤生物学特性及对vorasidenib的治疗响应 NanoGlio recapitulates IDH -mutant glioma biology and therapeutic response to vorasidenib Uijin Kim, Satoru Kawakita, Emily Miller, Wei Huang, Francisco Bustamante, Lauren Vanderpool, Chongming Jiang, Albert Lai, Zhaohui Wang
• 3332 · PDF PHLDA1下调导致MCF-7乳腺癌细胞形态改变和增殖增强的功能作用 Functional role of PHLDA1 down regulation leads to morphological changes and increased proliferation in MCF-7 breast cancer cells Ana Carolina Pavanelli, Flavia Rotea Mangone, Fernando M. Simabuco, Maria Aparecida Nagai
• 3333 · PDF PLK1介导的CHAF1A磷酸化促进前列腺癌中AR驱动的enzalutamide耐药 CHAF1A phosphorylation by PLK1 promotes AR-driven enzalutamide resistance in prostate cancer Sai Wu, Chaohao Li, Jia Peng, Xiaoqi Liu
• 3334 · PDF 人类Flower异构体hFWE4促进皮肤鳞状细胞癌中的角化 The human Flower isoform hFWE4 facilitates cornification in cutaneous squamous cell carcinoma Justin C. Rudd, Patrick T. Kuwong, Rachel E. Johnson, Louise N. Monga-Wells, Meghan Vo, Julia Russolillo, Shreya Reddy, Mallory Jacob, Hunter Litz, Changzhao Li, Andrew Siref, James A. Grunkemeyer, Laura A. Hansen
• 3335 · PDF Trop-1/EpCAM Thr115是癌细胞增殖的一种新型诱导因子,并驱动COVID-19中的过度增殖性肺损伤 Trop-1/EpCAM Thr115 is a novel inducer of cancer cell proliferation and drives hyperproliferative lung damage in COVID-19 Saverio Alberti, Milena Baldassarri, Marco Trerotola, Giulia Brunelli, Laura Bergantini, Benedetta tella, Giulia Rollo, Emanuela Guerra, martina ceci, Ludovica Pantalone, Elena Bargagli, Rossano Lattanzio, Antonino Moschella, Federica M. Previtera, Cristiana Bellan, Nicola La Francesca, Cristoforo Pomara, Network for Italian Genomes, GEN-COVID Multicenter Study, Alessandra Renieri, Chiara Fallerini
• 3336 · PDF cGAS/STING激活的巨噬细胞形成脂噬体以调节TME并促进肥胖相关胰腺癌的进展 cGAS/STING-activated macrophages form lipophagosomes to regulate TME and promote progression in obesity-associated pancreatic cancer Yi-ting Chen, Zu-Wei Wang, Jin-peng Lu, Hao-xiang Zhang, Shun-cang Zhu, Hong-yi Lin, Shi Chen

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