PO.TB10.15 · 肿瘤生物学
Extracellular Vesicles and Long-Range Tumor-Host Communication
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3340 · PDF 迈向细胞外囊泡分析在精准肿瘤学中的大规模临床应用 Toward large-scale clinical implementation of extracellular vesicle profiling for precision oncology Antonia Schubert, Nadine Winkler, Robert Ihnatko, Joscha Kraske, Sunanjay Bajaj, Michelle Neßling, Karsten Richter, Dirk Jäger, Guy Ungerechts, Oliver Sedlaczek, Jeroen Krijgsveld, Thomas Walle, Michael Boutros
- 3341 3341 聚焦超声开放血脑屏障产生独特的组织特异性细胞外囊泡图谱用于胶质母细胞瘤液体活检 Focused ultrasound BBB opening yields distinct, tissue-specific extracellular vesicle profiles for glioblastoma liquid biopsy Andrew Thede, Zehra Demir, Khondamir Imomnazarov, Stefanyda Maslova, Rachel Short-Miller, Sean Lodmell, Kelley VanVaerenberghe, Claire Seibold, Adam LaBonte, Katie Havranek, Natasha D. Sheybani
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3342 · PDF Mito-EV 驱动的线粒体转移:胶质母细胞瘤中铁死亡的触发因素 Mito-EV-driven mitochondrial transfer: A trigger for ferroptosis in glioblastoma Junbo Liao, Shuhan Cao, Ka Kit Gilberto Leung, Karrie. M Kiang
- 3343 3343 癌症相关成纤维细胞来源的细胞外囊泡中的 ATP6V1C1 影响肺腺癌的转移和治疗敏感性 ATP6V1C1 in cancer-associated fibroblast-derived extracellular vesicles affects the metastasis and therapeutic sensitivity of lung adenocarcinoma Xuanming Chen, Jue Li, Kai Xiao
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3344 · PDF Pyk2 通过囊泡运输在胶质母细胞瘤细胞中调控 Rab 蛋白 Pyk2 controls rab proteins by vesicle trafficking in glioblastoma cells Neisha Marie Ramirez Serrano, Lilia Kucheryavykh
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3345 · PDF FGFR2 扩增癌症中通过细胞外囊泡进行的功能性染色体外 DNA 水平转移 Horizontal transfer of functional extrachromosomal DNA via extracellular vesicles in FGFR2-amplified cancer Irene Salamon, Giulia Gallerani, Jens Luebeck, Gianluca Storci, Simone Spandau, Beatrice Fontana, Alessia Soru, Mattia Riefolo, Marco Pagano Mariano, Ilaria Pace, Andrea Cavazzoni, Vineet Bafna, Massimiliano Bonafe', Manuela Ferracin
- 3346 3346 使用 3D 器官芯片平台模拟乳腺癌细胞外囊泡介导的淋巴管糖萼降解 Modeling breast cancer extracellular vesicle-mediated degradation of the lymphatic glycocalyx using a 3D organ-on-chip platform Justin Lau, Issahy Cano, Esak Lee
- 3347 3347 小型和大型细胞外囊泡的蛋白质组学和功能分化揭示卵巢癌进展的亚型特异性驱动因素 Proteomic and functional divergence of small and large extracellular vesicles reveal subtype-specific drivers of ovarian cancer progression Kalpana Deepa Priya Dorayappan, Fries Brian, Wei Fu, Ganesh Yadaigiri, Lakshmi Narasimhan Chakrapani, Sydney Wiggins, Shyam Sundaram, Thangavel Muthusamy, Sudhiksha Anbu Chelian, Gabriela S. Vendrell, Qi-En Wang, David E. Cohn, Lianbo Yu, David O’Malley, Colin Hisey, Selvendiran Karuppaiyah
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3348 · PDF 脂肪肉瘤来源的细胞外囊泡抑制 STING 信号传导并损害巨噬细胞的固有免疫激活 Liposarcoma-derived extracellular vesicles suppress STING signaling and impair innate immune activation in macrophages Qi Zhang, Patricia Sarchet, Fernanda C. C. de Faria, Priya Dhawale, Sydney Rentsch, Roma Karna, Valerie Grignol, Jing Wang, Raphael Pollock, Federica Calore
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3350 · PDF 从前列腺癌患者中分离和表征前列腺特异性细胞外囊泡 Isolation and characterization of prostate-specific extracellular vesicles from prostate cancer patients Shashi Anand, Emily Ridden, Ty W. Turner, Kunwar Somesh Vikramdeo, Ramya Krishna Velagapudi, Denise C. Cornelius, Ajay Pratap Singh, Xinchun Zhou
- 3351 3351 探究cofilin-1过表达细胞分泌的细胞外囊泡对人肺癌细胞迁移和侵袭能力的影响 Exploring the effects of extracellular vesicles secreted by cofilin-1 overexpressing cells on the migration and invasion ability of human lung cancer cells Huang Bo-Han, Yi-Jang Lee
- 3353 3353 焦亡来源的细胞外囊泡作为近红外光免疫治疗中的关键免疫激活因子 Pyroptosis-derived extracellular vesicles as key immunoactivators in near-infrared photoimmunotherapy Fan Chen, Yuxuan Li, Ye Lu, Peng Guo, Weifeng Qian, Wei-Hong Tan
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3354 · PDF 放化疗增加细胞外囊泡释放,导致直肠癌细胞系的治疗抵抗 Chemoradiation treatment increases extracellular vesicle release causing treatment resistance in rectal cancer cell lines Vivek Somasundaram, Jeremie M. P. Lever, Regina Irwin, Teresa C. Beamon, Karin M. Hardiman
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3355 · PDF RD3缺陷决定的外泌体遗传货物转变引导神经母细胞瘤的进展性演变 Exosomal genetic cargo shift dictated by RD3 deficiency steers progressive neuroblastoma evolution Afsana Parveen Jahir Hussain, Sreenidhi Mohanvelu, Loganayaki Periyasamy, Poorvi Subramanian, Sheeja Aravindan, Natarajan Aravindan
- 3356 3356 肿瘤来源外泌体通过重编程肿瘤相关巨噬细胞促进肾癌进展 Tumor-derived exosomes promote renal cancer progression via reprogramming of tumor-associated macrophages Jinlu Dai, Suguru Kadomoto, Tyler Robinson, Evan T. Keller
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3358 · PDF 乳腺癌期间祖细胞中性粒细胞外流至外周的后果 The consequences of progenitor neutrophil evacuation into the periphery during breast cancer Mariah Branson, Carolyn Schroeder, Melissa Meyer
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3359 · PDF 胃肠道癌性腹膜转移中腹腔灌洗液细胞外囊泡的独特特征 Distinct profile of peritoneal lavage fluid extracellular vesicles in gastrointestinal carcinomatosis Fatemeh Tajik, Vinodh Kumar Radhakrishnan, Alex N. Dang, Aaqil M. Khan, Melanie Roman, Shaun Daly, Areg Grigorian, Cristobal Barrios, Sigrid Burruss, Maheswari Senthil
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3360 · PDF 环境对肿瘤来源外泌体分泌的影响 Environmental impact on the secretion of tumor-derived exosomes Haylie Pullan
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3361 · PDF 使用 Kairos cLDEP 颗粒分选仪精确分离肿瘤相关 EV 亚群 Precise isolation of tumor-relevant EV sub-populations using the Kairos cLDEP particle sorter Boyang Su, Shujun Xu, Reese Wunsche, Dennis Lee, Hon Leong
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3362 · PDF 脂质纳米探针磁珠实现高纯度血浆 EV 分离,用于广谱癌症生物标志物检测 Lipid nanoprobe magnetic beads enable high-purity plasma EV isolation for broad-spectrum cancer biomarker detection Qiuyan Ma, Dehe Kong, Sidhant Narula, Jin-Qiu (Jessie) Chen
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3363 · PDF 成纤维细胞外泌体诱导基质基质组装及乳腺肿瘤生长和转移 Fibroblast exosomes induce stromal matrix assembly and breast tumor growth and metastasis Bong Hwan Sung, Merlyn Emmanuel, Metti Gari, Jorge Guerrero, Maria Virumbrales-Muñoz, David Inman, Evan Krystofiak, Alan Rapraeger, Suzanne M. Ponik, Alissa M. Weaver
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3364 · PDF 酸性细胞外环境中肿瘤细胞来源的外泌体抑制肝转移 Exosomes derived from tumor cells in acidic extracellular environment inhibit liver metastasis Bei Jin, Weijia Peng, Jingxuan Pan
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3365 · PDF 由器官间串扰介导的肿瘤纤维化新机制 Novel mechanism of tumor fibrosis mediated by interorgan crosstalk Akiho Nishimura, Takatsugu Ishimoto, Takashi Semba, Atsuko Yonemura
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3366 · PDF 肌肉铁过载促进癌症恶病质诱导的肌肉萎缩 Muscle iron overload contributes to cancer cachexia-induced muscle wasting Subin Pyo, Yichi Zhang, Anna Barbeau, ChiHin Feng, Amit Roopan, Ning Liu, Eric N. Olson, Matthew G. Vander Heiden
- 3367 3367 线粒体钙单向转运体通过 NETosis 介导的骨骼肌萎缩驱动胰腺导管腺癌中的癌症恶病质 Mitochondrial calcium uniporter drives cancer cachexia in pancreatic ductal adenocarcinoma through NETosis-mediated skeletal muscle atrophy Xiuchao Wang, Jihui Hao
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3368 · PDF 代谢物驱动的翻译后修饰调控胶质母细胞瘤微环境中的线粒体稳态 Metabolite-driven post-translational modifications regulate mitochondrial homeostasis in the glioblastoma microenvironment Zhongsheng You, Karrie Kiang, Gilberto Leung
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7149 · PDF 由肿瘤微环境介导的 SIRT1 在胶质母细胞瘤中的矛盾作用 The paradoxical role of SIRT1 in glioblastoma mediated by the tumor microenvironment Anza Mnahal, Wanjun Tang, Bo Chen, Karrie Mei Yee Kiang, Gilberto Ka Kit Leung