Late-Breaking Research: Tumor Biology 2

• LB301 · PDF 靶向p300/CBP消除HOXB13缺失诱导的脂肪生成和肿瘤转移 Targeting p300/CBP abolishes HOXB13 loss-induced lipogenesis and tumor metastasis Xiaodong Lu, Liu Peng, Qi Chu, Samantha Ye, Mingyang Liu, Maha Hussain, Mehmet A. Bilen, Lara R. Harik, Jonathan Melamed, Jonathan C. Zhao, Jindan Yu
• LB302 · PDF 利用单细胞空间基因组学研究乳腺癌脑转移的免疫微环境 Investigation of the immune microenvironment of breast cancer brain metastasis using single-cell spatial genomics Eva Zhao, Isam Adam, Angela Lincy Prem Antony Samy, Jacob Insua-Rodríguez, Pascal Naef, Sharmila Mallya, Jenny Wu, Delia F. Tifrea, Robert A. Edwards, Ahmed Mohyeldin, Devon A. Lawson
• LB303 · PDF C3a-C3aR1信号促进皮肤鳞状细胞癌的侵袭 C3a-C3aR1 signaling promotes invasion of cutaneous squamous cell carcinoma Lauri Heiskanen, Liisa Nissinen, Elina Siljamäki, Pekka Rappu, Ujjwal Suwal, Jaakko S. Knuutila, Jutta Huvila, Jyrki Heino, Veli-Matti Kahari, Pilvi Riihilä
• LB304 · PDF 配体依赖性Wnt信号驱动胃癌转移龛的形成 Ligand-dependent Wnt signaling drives metastatic niche formation in gastric cancer Hiroko Oshima, Yuichiro Furutani, Noriyuki Inaki, Nick Barker, Masanobu Oshima
• LB305 · PDF CARP-1/CCAR1是三阴性乳腺癌转移的新型调控因子 CARP-1/CCAR1 is a novel regulator of triple-negative breast cancer metastasis Magesh Muthu, Sijana Dzinic, Hunter Dlugas, Seongho Kim, Min Wu, Russell L. Finley, Lisa A. Polin, Arun K. Rishi
• LB306 · PDF 空间转录组学揭示原发部位内皮细胞EMT重编程驱动转移性葡萄膜黑色素瘤的免疫抑制并预测不良生存 Spatial transcriptomics reveals primary-site endothelial EMT reprogramming that drives immunosuppression in metastatic uveal melanoma and predicts poor survival Sylvia Burris, Gurdeep Singh
• LB307 · PDF FUS缺失通过上调CD36表达诱导神经内分泌分化样表型并促进肺癌软脑膜转移 FUS ablation induces neuroendocrine-differentiation-like phenotypes and promotes leptomeningeal metastases in lung cancer through upregulating CD36 expression Peng Li, Shouheng Lin, Kai Yin, Mei-mei Zheng, Hai-yan Tu, Yang-Si Li, Yi-Long Wu
• LB308 · PDF 胰腺癌转移受一段十一氨基酸序列的转录调控 Pancreatic cancer metastasis is transcriptionally regulated by an eleven amino-acid sequence Guillem Fuertes Marin, Daniele DiBiagio, Riddhi P. Sontakke, Eleni Maniati, Jenkins H. Benjamin, Gareth J. Thomas, John Francis Marshall
• LB309 · PDF Y染色体丢失通过单细胞表观遗传和转录异质性驱动肺腺癌的细胞可塑性 Y chromosome loss drives cellular plasticity through single-cell epigenetic and transcriptional heterogeneity in lung adenocarcinoma Kathleen Schlüter, Mei-Ju May Chen, Gizem Altun, Sergio Manzano Sanchez, Dung-Chi Wu, Nan Zhang, Ofir Griess, Luc Husemann, Fabian Bradic, Joseph Cornick, Oliver Mücke, Riccardo Moro, Katherine Kelly, Sara Chocarro, Etienne Sollier, Maria Jose Alonso-De Gennaro, Siavash Mansouri, Madeleine Dorsch, Patricia Munteanu, Balazs Hegedüs, Hauke Winter, Laura V. Klotz, Mark Kriegsmann, Felix JF Herth, Marc A. Schneider, Daniel Kazdal, Albrecht Stenzinger, Alexander Schramm, Felix J. Hartmann, Pavlo Lutsik, Ursula Klingmüller, Rajkumar Savai, Rocio Sotillo, Barbara M. Grüner, Guy Ron, Efrat Shema, Michael Scherer, Christoph Plass, Maria Llamazares-Prada
• LB310 · PDF 脂肪靶向电刺激抑制肥胖相关TNBC的转移 Adipose-targeted electrical stimulation suppresses metastasis in obesity-associated TNBC Sohae Yang, Hyun Gyu Kang, Minseok S. Kim
• LB311 LB311 剖析塑造免疫抑制性肿瘤微环境的干性相关分子环路 Dissecting stemness associated molecular circuits that shape the immune suppressive tumor microenvironment Yuxuan Miao
• LB312 · PDF SOX2驱动的干性是食管鳞状细胞癌治疗前患者来源类器官长期维持的关键决定因素 SOX2-driven stemness as a key determinant for long-term maintenance of pre-treatment patient-derived organoids in esophageal squamous cell carcinoma Akito Shimizu, Kazuhiro Noma, Hajime Kashima, Yasushige Takeda, Yohei Mizusawa, Tasuku Matsumoto, Hijiri Matsumoto, Tomoyoshi Kunitomo, Masashi Hashimoto, Naoaki Maeda, Satoru Kikuchi, Shunsuke Tanabe, Hotaka Kawai, Toshiaki Ohara, Hiroshi Tazawa, Hiroshi Nakagawa, Toshiyoshi Fujiwara
• LB313 · PDF 推进iPSC来源CAR NK细胞疗法以增强实体瘤治疗 Advancing iPSC derived CAR NK cell therapy for enhanced solid tumor treatment Olga Cohen, Ranganatha R. Somasagara, Lindsay Bailey-Steinitz, Rateb Mir, Namritha Ravinder
• LB314 · PDF 全基因组甲基化测序强烈提示某些肺腺癌具有新的非干细胞起源 Whole genome methylation sequencingstrongly suggests a novel, non-stem cell origin for some lung adenocarcinomas Nicholas Juul, Diego Almanza, Maximilian Diehn, Tushar Desai
• LB315 · PDF 靶向内体溶酶体转运以克服三阴性乳腺癌的紫杉醇耐药 Targeting endolysosomal trafficking to overcome paclitaxel resistance in triple-negative breast cancer Rajiv Pathak, Prabhash Nath Tripathi, Veronica Piedra, Chandrabose Karthikeyan, Amit K. Tiwari
• LB316 · PDF 胃食管腺癌中FOXA2相关的化疗耐药：一项单细胞转录组探索性分析 FOXA2-associated chemoresistance in gastroesophageal adenocarcinoma: A single-cell transcriptomic exploratory analysis Shuyuan Wang, Qian Qiu, Sanjima Pal, Ece Ozmen, Ruoyu Ma, Cédric Julien, Wotan Zeng, Betty Giannias, France Bourdeau, Nicholas Bertos, Swneke Bailey, Lorenzo Ferri

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