PO.EN01.02 · 内分泌肿瘤
Signaling Pathways, Metabolism, and Emerging Therapeutic Targets
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- 5012 5012 多组学分析揭示髓系免疫细胞中 LXR 选择性调节的配体和细胞特异性调控程序 Multiomic profiling reveals ligand and cell specific regulatory programs of LXR selective modulation in myeloid immune cells Yifan Fei, Rajendra K C, Mark Flory, Natalia Julianna Krawczynska, Yu Wang, Kevin T. VanBortle, Hisham Mohammed, Erik R. Nelson
- 5013 5013 利用多组学分析对甲状腺滤泡癌中 DICER1 突变及双打击肿瘤发生机制的全面表征 Comprehensive characterization of DICER1 mutations and two hit tumorigenesis mechanisms in follicular thyroid carcinoma using multi-omics analysis Dakyung Lee, Young Ah Lee, Yeonju Kyoung, Seong-Keun Yoo, Sun-Wha Im, Jaeyong Choi, Yoo Hyung Kim, Dohyun Han, Young Joo Park, Jong-Il Kim
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- 5019 5019 针对新型口服雌激素受体（ER）降解剂（PROTAC）AZD4241的临床前机制性PK/PD/疗效建模，以支持早期临床开发中的剂量选择 Preclinical mechanistic PK/PD/Efficacy modeling for AZD4241, a novel oral estrogen receptor (ER) degrader (PROTAC), to support dose selection during early clinical development Ana Quiroga, Pablo Morentin Gutierrez, Lynet Nyoni, Natalie Cureton, Mandy Lawson, Aaron Smith, Thomas Hayhow, Neil Gibson
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