PO.ET02.10 · 实验与分子治疗
Drug Combinations, Repurposing, and Differentiation
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- 4455 4455 Efficacy of Tumor Treating Fields (TTFields) together with standard chemotherapy and PD-L1 blockage in preclinical models of small cell lung carcinoma Rotem Engelman, Lina Somri-Gannam, Talya Borkum, Roni Blatt, Daria Gerasimova, Shay Cahal, Catherine Tempel Brami, Mai Shai, Yiftah Barsheshet, Eyal Dor-On, Itai Tzchori, Adi Haber, Moshe Giladi, Uri Weinberg, Yoram Palti
- 4456 4456 Tumor Treating Fields (TTFields) potentiate antitumor and immune responses to standard immunochemotherapy in non-small cell lung cancer models Boris Brant, Yiftah Barsheshet, Tali Voloshin, Tal Kan, Tharwat Haj Khalil, Simona Zisman-Rozen, Lilach Koren, Avital Vorontsov, Bella Koltun, Cfir David, Anat Klein-Goldberg, Efrat Zemer-Tov, Adi Haber, Moshe Giladi, Uri Weinberg, Yoram Palti
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- 4462 4462 Nebivolol inhibits cell growth, inhibits autophagic flux, and enhances growth inhibition in combination with bicalutamide in prostate cancer cells Swarnil Mandal, Chia-Ling Wu, Shivaani S. Kanna, Wangjia Cao, Meghana V. Trivedi
- 4463 4463 Repurposing the anti-dementia drug memantine, (a dualalpha7-nAChR NMDAR antagonist) as an anti-cancer agent in human squamous cell lung cancer Javan Christian, Sarah L. Miles, Kritsa L. Denning, Kushal J. Modi, Reagan S. Light, Piyali Dasgupta, Yi Charlie Chen
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- 4465 4465 Miconazole induces cell cycle arrest and apoptosis in prostate cancer cells via a p53-mediated pathway: A Drug repurposing strategy Eswara Naga Hanuma Kumar Ghali, Lindsey Shim, Rahul Tiwari, Rajasekhar Baru, Anupam Dhasmana, Chang Ryan Jisoo, Sung Yun Jung, Vivek Kumar Kashyap, Neeraj Chauhan, Subhash C. Chauhan, Murali M. Yallapu
- 4466 4466 Clinical-grade CK2 inhibitor CX-4945 synergistically enhances venetoclax-mediated antileukemic activity in preclinical acute myeloid leukemia models Upendarrao Golla, Muhammad Danial, Rajesh Rajaiah, Marudhu Pandiyan Shanmugam, Koby Duke, Katherine Mercer, Yi Qiu, Sinisa Dovat, Yasin Uzun, Hong Zheng, Suming Huang, Chandrika G. Behura
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- 4470 4470 Combination of NAMPT inhibitors plus pyrimidine analog antimetabolites floxuridine and 5-FU impair rhabdomyosarcoma proliferation and survival Jamie Gudyka, Choh Yeung, Senna Munnikhuysen, Christina M. Robinson, Amy James, Xiaohu Zhang, David Holland, Michele Ceribelli, Simone Difilippantonio, Craig J. Thomas, Christine M. Heske
- 4471 4471 Synergistic metabolic inhibition with 2-DG and metformin loaded electrospun scaffolds disrupts glioblastoma redox balance and glycolytic output Bryce William Jewett
- 4472 4472 Combination of medroxyprogesterone acetate (MPA) and a WEE1 or ATR inhibitor enhances anti-tumor activity of estrogen receptor-positive endometrial cancer cells Yuki Takemoto, Yasuto Kinose, Li Han, Mai Koizumi, Yan Wang, Kanako Kasuya, Aasa Shimizu, Erika Nakatsuka, Mahiru Kawano, Kenjiro Sawada, Michiko Kodama
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- 4474 4474 Cannabidiol enhances etoposide efficacy in non-small cell lung cancer by engaging a p53-mTOR-TFEB lysosomal death program Youngsic Jeon, Hyukjoon Kwon, Young Nyun Park, Taejung Kim, Young-Joo Kim
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- 4476 4476 Repurposing PARP inhibitors in molecularly defined subgroups of peritoneal metastatic colorectal cancer (pmCRC): Preclinical analysis of patient-derived xenograft (PDX) models Mathias Dahlmann, Beate Rau, Safak Gül-Klein, Bernadette Brzezicha, Marlen Keil, Antje Wengner, Jens Hoffmann, Sebastian Stintzing, Ulrike S. Stein, Wolfgang Walther, Loredana Vecchione
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