PO.ET08.01 · 实验与分子治疗
Strategies to Enhance the Therapeutic Index of Radiotherapy
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- 4624 4624 Investigation of the efficacy of reduced coenzyme Q10 (CoQ10) for alleviating acute intestinal toxicity associated with pelvic radiotherapy: A randomized, placebo-controlled, double-blind comparative study Satoshi Seno, Akifumi Kajiwara, Yasuyuki Shimizu, Kazuma Iwashita, Kana Kobayashi, Qin Qin, Qu Zhang, Hatamei Takabayashi, Kanako Suda, Hiroki Kawaguchi, Takeaki Ishihara, Daisuke Miyawaki, Sae Murakami, Yoshito Terai, Ryohei Sasaki
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- 4628 4628 Mitochondrial serine/threonine phosphatase, phosphoglycerate mutase 5 (PGAM5) is a novel target to promote abdominal radiotherapy Shujah Hamid Rehman, Rishi Man Chugh, Payel Bhanja, Stacey Krepel, Subhrajit Saha
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- 4630 4630 CD46-targeted dual-modality alpha-particle and cytotoxic payload-loaded antibody for enhanced treatment of metastatic castration-resistant prostate cancer Anil Bidkar, Scott Bidlingmaier, Anju Wadhwa, Kondapa Naidu Bobba, Shubhankar Naik, Cheng Xue, Athira Raveendran, Megha Basak, Jonathan Chou, Rahul Aggarwal, Henry VanBrocklin, Youngho Seo, Bin Liu, Robert Flavell
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- 4633 4633 Theranostic evaluation of 68 Ga-PMSA, 177 Lu PSMA therapy, and biomarker guided immunotherapy and DDR inhibitor combinations in LNCaP prostate cancer xenografts Juliana Maynard, Anita Liu, Benedetta Arno, Tracy Hall, William Drewe, Kerry Shea, Andrzej Rutkowski, Grace Haydon, Tiffany-Jane Allen, Fiona Yau, Liviu Lucaciu, Mikaela Griffiths, Gayle Marshall
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- 4636 4636 Deciphering radiation sensitivity identifies MDM2 as a targetable driver of synergistic radiosensitization in TP53 wild-type lung adenocarcinoma Chan Hoon Maeng, Jieon Hwang, Joong Bae Ahn, Sang Joon Shin
- 4637 4637 Alpha-particle radiotherapy combined with anti-CTLA-4 synergistically overcomes radioresistance and induces local and systemic antitumor immunity in PDAC Marco Reis, Poliana C. Marinello, Walison Augusto da Silva Brito, Scott Bright, Mark Wasley, Alexandre Rubinstein, Ronen Sega, Vered Bachar, Gabriel O. Sawakuchi
- 4638 4638 Oncolytic herpes simplex virus, M002, increases the antitumor radiation response by decreasing the G2/M arrest in murine rhabdomyosarcoma orthotopic allograft cells Maryam G. Shaikh, Nazia Nazam, Morgan L. Brown, Pranava Nande, Ali M. Eakes, Shamza Manzoor, Joel C. Opara, James M. Markert, Jamie M. Aye, Elizabeth A. Beierle
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- 4641 4641 Highly soluble prodrug boronophenylalanine (L-BPA) dipeptide, exhibits notable tumor suppression whilst inducing cancer vaccine effect post neutron irradiation treatment Samkeliso Dlamini, Michael Torgov, Arthur Raitano, Jason Quintana, Tioga Martin, Chunying Zhang, Maria Christina Malinao, Maki Ikeura, Linnette Capo, Karen Morrison, Robert Dorn, Kotaro Matsumoto, Aoi Komatsu, Yuya Higashi, Takushi Takata, Yoshinori Sakurai, Minoru Suzuki, Fuyuhiko Tamanoi, Kendall Morrison
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- 4643 4643 Microsatellite instability as a determinant of chemoradiotherapy sensitivity in colorectal cancer: Integrated clinical, radiomic, and 3D organoid-based analyses Hyowon Hong, Shin Kim, Sang Jun Byun, Seong Kyu Baek, hyewon lee, sung wook bae
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- 4646 4646 Validation of a panel of fibroblast activation protein expressing cell line derived xenograft models as a platform for the development of targeted radioligand therapeutics Michael Batey, James Suchy, Taylor Hotz, Michael Milhollen, Kayla Duval, Jackson Chan, Karen Gelinas, Michael Bruce, Michelle Petrozzi, William Maccuaig, Neil Rollins, Jennifer Tavares, Erin Snay, Kyeara Mack-Henry, Soumya Ullas
- 4647 4647 Development and validation of a panel of cell line derived xenograft models representing multiple tumor indications for the evaluation of targeted radioligand therapeutics Michael Batey, James Suchy, Taylor Hotz, Michael Bruce, Jennifer Tavares, Erin Snay, Neil Rollins, Jackson Chan, Karen Gelinas, Kayla Duval, William Maccuaig, Michael Milhollen, Michelle Petrozzi, Kyeara Mack-Henry, Soumya Ullas
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