PO.CL07.03 · 临床研究
Targeting DNA Repair, Cell Cycle, and Tumor Metabolism
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- 1258 1258 利用组合纳米药物同时降解BRD4和破坏基质以对抗胰腺导管腺癌 Harnessing combinatorial nanomedicine for simultaneous BRD4 degradation and stromal disruption against pancreatic ductal adenocarcinoma Drishti Rathod, Ketankumar Patel
- 1260 1260 LIPA抑制通过诱导ER应激和增强DNA损伤提高DNA损伤剂在卵巢癌中的治疗疗效 LIPA inhibition enhances the therapeutic efficacy of DNA-damaging agents in ovarian cancer through induction of ER stress and enhancing DNA damage Durga Meenakshi Panneerdoss, Tae-Kyung Lee, Khaled Mohamed Nassar, Gaurav Sharma, Scott Terry Elmore, Henry Neal, William Cole Arnold, Edward Kost, Suryavathi Viswanadhapalli, Jung-Mo Ahn, Ganesh V. Raj, Ratna K. Vadlamudi
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- 1264 1264 RBM10野生型/缺陷型EGFR突变肺癌患者来源模型中有限的凋亡反应可通过EGFR与BCL-2/BCL-xL联合抑制而克服 Limited apoptotic response in RBM10 wild type/deficient EGFR-mutant lung cancer patient-derived models overcome by combined EGFR and BCL-2/BCL-xL inhibition Jonathan Wesley Riess, Hongyong Zhang, Jasmine Diaz Sezati, Peyton Apruzzese, Dongguang Wei, Tiffany Le, Luis G. Carvajal-Carmona
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- 1276 1276 双重表观遗传-激酶靶向以克服肝细胞癌的耐药与免疫逃逸 Dual epigenetic-kinase targeting to overcome resistance and immune evasion in hepatocellular carcinoma Kyounghyun Kim, HongDuck Yun, Gabin Kwon
- 1277 1277 以协同方法靶向异质性克服胶质母细胞瘤耐药：TTFields 刺激与 tmCLIC1 损害 Overcoming glioblastoma resistance by targeting its heterogeneity with a synergistic approach: TTFields stimulation and tmCLIC1 impairment Francesca Cianci, Elisa Meraviglia, Guido Rey, Stefania Castiglione, Antonio M. Polito, Sara Torabi, CHIARA MERCURIO, Dietmar Krex, Tatiana Vorobyov, Kerem Wainer-Katsir, Martin Gabay, YAARA PORAT, Roni Blatt, Ori Braten, Tullio Florio, Itai Tzchori, Michele Mazzanti
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