PO.IM01.06 · 免疫学
CAR T Cell Functional Enhancement
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- 4272 4272 谷氨酸-草酰乙酸转氨酶2（GOT2）作为CAR-T细胞代谢适能的双功能增强剂 Glutamic-oxaloacetic transaminase 2 (GOT2) as a dual-functional enhancer for CAR-T cell metabolic fitness Xiangyi Fang, Shadab Kazmi, Andre Kelly, Xiaoling Jin, Alison Jaccard, Nathaniel W. Snyder, Alexander A. Shestov, Saba Ghassemi, Roddy S. O'Connor
- 4273 4273 CD19-CAR T细胞制造过程中的环境调控在皮下NALM6肿瘤模型中影响抗肿瘤效力 Environmental conditioning during CD19-CAR T cell manufacturing impacts antitumor potency in a subcutaneous NALM6 tumor model Candy Garcia, Anita J. Zaitouna, Abriel Czachorowski, Lauren Kucharczyk, Natalie Czeryba, Philip Edward Lapinski, Andrea Hodgins-Davis, Thomas Sullivan, Yelena Bronevetsky, NINGCHUN LIU, Sheri Barnes, Shannon Eaker, Scott Wise, James Lim
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- 4279 4279 采用CD16A信号结构域工程化的PSMA靶向CAR-T细胞在前列腺癌模型中减少细胞因子输出同时保留抗肿瘤活性 A PSMA-targeted CAR-T cell engineered with a CD16A signaling domain mitigates cytokine output while retaining antitumor activity in prostate cancer models Parv Barot, Hittu Matta, Sunju Choi, Gong Songjie, Bryant Bravo, Elton Zho, Hsing-Yu Wu, Sam Lin, Zhuoyue Yang, Preet M. Chaudhary
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