PO.MCB09.06 · 分子与细胞生物学
Metabolic Alterations in Colorectal and Gastrointestinal Cancers
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- 4704 4704 游离脂肪酸破坏胆固醇稳态通过调控CCL20促进结肠癌 Disruption in cholesterol homeostasis by free fatty acid promote colon cancer by modulating CCL20 Janani Muralidharan, Ankit Bhatt, Jaliya M. Mims, Gene Hughes, Paige Marcelline, Sejong Bae, Shailesh Singh, Hina Mir
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- 4706 4706 力学等离子体学：整合纳米等离子体材料与刚度可调水凝胶以实现实时、无标记的细胞分析 Mechanoplasmonics: Integrating nanoplasmonic materials and stiffness tunable hydrogels for real-time, label-free cellular analysis Cason M. Hancock, Harlie Rios, Alexander McGhee, Swarna Ganesh
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- 4710 4710 FFPE人体组织的全面代谢组学分析揭示结直肠癌的关键代谢重编程及相关通路 Comprehensive metabolomic profiling of FFPE human tissues reveals key metabolic reprogramming in colorectal cancer and associated pathways Tom Cohen, Ashima Mehta, Adam Richardson, Monil Gandhi, Douglas Guzior, Kevin Cho, Ethan Stancliffe, Gary Patti
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- 4712 4712 基于KRAS状态靶向NRF2调控的多胺和谷胱甘肽代谢可增强结直肠癌的化疗疗效 Targeting NRF2-regulated polyamine and glutathione metabolism enhances chemotherapy efficacy in colorectal cancer based on KRAS status Jiamin Li, Jieqing Feng, Fuyue Wang, Yingjie Zhang, Hong Yan, Zongwei Cai
- 4713 4713 靶向癌症相关成纤维细胞中的糖原代谢可缓解免疫抑制并抑制结直肠癌恶性程度 Targeting glycogen metabolism in cancer-associated fibroblasts alleviates immunosuppression and inhibits colorectal cancer malignancy Xudong Zhu, Yuning Zhou, Haoxiang Zhang, Yinping Jiang, Jinpeng Liu, Chi Wang, B. Mark Evers, Qingding Wang
- 4714 4714 肿瘤相关巨噬细胞的肌酸代谢重编程增强hnRNPA1相分离并促进结直肠癌干性和复发 Tumor-associated macrophage creatine metabolic reprogramming enhances hnRNPA1 phase separation and promotes colorectal cancer stemness and recurrence Zhengran Zhou, Xuanhui Liu, Yifan Zheng, Zhengyu Wei, Zerong Cai, Yufeng Chen, Peishan Hu, Xiaojian Wu
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- 4717 4717 TBK1/IKKbeta介导的CAD磷酸化将嘧啶合成阻断和化疗增敏与先天免疫激活联系起来 TBK1/IKKbeta-mediated CAD phosphorylation links pyrimidine synthesis blockade and chemosensitization to innate immune activation Taolin Xie, Chi Liang, Hansong Xia, Anjie Lu, Chao Qin, Xinchi Xie, Wayne Yeh, Pinghui Feng
- 4718 4718 氧化还原重编程保护结肠癌细胞在葡萄糖剥夺下免于双硫死亡 Redox reprogramming protects colon cancer cells from disulfidptosis under glucose deprivation Elimelech Nesher, Subha Ranjan Das, Igor Koman
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- 4724 4724 血浆氧化三甲胺（TMAO）水平升高与免疫治疗的可切除胃食管癌和胸膜间皮瘤中更好的临床和分子应答相关 Elevated plasma trimethylamine-N-oxide (TMAO) levels correlate with better clinical and molecular responses in immunotherapy-treated resectable gastroesophageal cancer and pleural mesothelioma Rachel J. Keogh, Paul K. Lee, N.V. Rajeshkumar, Blair V. Landon, Joshua E. Reuss, Jaime Wehr, Gavin Pereira, Amna Jamali, Noushin Niknafs, Ronan J. Kelly, Ali H. Zaidi, Josephine L. Feliciano, Julie R. Brahmer, Vincent K. Lam, Patrick M. Forde, Chi V. Dang, Valsamo Anagnostou
