AACR Project GENIE: Genomic Characterization

• 4096 · PDF A pan-pediatric gene-regulatory network analysis reveals druggable dependencies across pediatric solid tumors Daniel Lee, Abid A. Reza, Syed A. Bukhari, Jun S. Wei, Hsein-Chao Chou, Xinyu Wen, Andrew S. Brohl, Javed Khan
• 4097 · PDF cBioPortal for cancer genomics Ino de Bruijn, Tali Mazor, Gaofei Zhao, Manda Wilson, Avery Wang, Floris Vleugels, Pim van Nierop, Henk-Jan van den Ham, S. Onur Sumer, Jessica Singh, Baby A. Satravada, Oleguer Plantalech, Angelica Ochoa, Zain-ul-Abideen Nasir, Ramyasree Madupuri, Pieter Lukasse, Aaron Lisman, James Lindsay, Xiang Li, Bryan Lai, Ritika Kundra, Priti Kumari, Sowmiyaa Kumar, Tim Kuijpers, James Ko, Zeynep Karagöz, Karthik Kalletla, Prasanna K Jagannathan, Jason Hwee, Guizela Huelsz Prince, Charles Haynes, Benjamin Gross, Zhaoyuan Fu, Ruslan Forostianov, Calla Chennault, Rima AlHamad, Ugur Dogrusoz, Allison Heath, Adam C. Resnick, Trevor J. Pugh, Chris Sander, Jianjiong Gao, Nikolaus Schultz, Ethan Cerami
• 4099 · PDF Genomic and clinical landscape of 10,000 Korean pan-cancer patients reveals molecular determinants of prognosis and therapeutic response: K-MASTER program Ji Yoon Lee, Jisoo Hong, Kyong Hwa Park, Soohyeon Lee, Jwa Hoon Kim, Ju Won Kim, Ji Won Lee, Yonghwa Choi, Doyoon Kim, Yoonji Kim, Woo Young Jang, Jiwon Kim, You Jin Song, Dayoung Lee, Hyeonmin Jeong, Wooseok Lee, Yoon Ji Choi, Jason K. Sa
• 4100 · PDF Large language models for tumor genomic interpretation Jennifer Yu, Madison Darmofal, Michele Waters, January Choy, Thinh N. Tran, Chenlian Fu, Leah Morales, Kaicheng U, Ross L. Levine, Nikolaus Schultz, Michael F. Berger, Quaid Morris, Justin Jee
• 4102 · PDF EGFR mutation subtype modifies the clinical impact of TP53 functional loss on brain metastasis and survival in lung cancer Lexi Li, Yiye Wong, Nathan Yan, J. Nicholas Bodor, Yunyun Zhou
• 4103 · PDF Dynamic co-mutation patterns and therapeutic implications in BRAF-altered malignancies: Evidence from AACR Project GENIE Mohamed M. Khamis, Vivek Subbiah, Mohamed Gouda
• 4104 · PDF The genomic landscape of skin adnexal carcinomas in the AACR GENIE database: Implications for precision cancer medicine Valbert Oliveira Costa Filho, Mariana Macambira Noronha, Pedro Robson Costa Passos, Carlos Diego Holanda Lopes, Giuseppe G. F. Leite, Carlos Wagner de Souza Wanderley, Sam D. Saibil, Danielle Calheiros Campelo Maia, Erick F. Saldanha
• 4105 · PDF Distinct age associated genomic landscapes in colorectal, pancreatic, small bowel, and anal cancers: A pan gastrointestinal analysis of 34,000 tumors from AACR Project GENIE v18.0 Ahmed Abdelhakeem, Nency Ganatra, Dina Elantably, Tayo Adeoye, Nayef H. Abdel-Razeq, Mosalem M. Osama, Hani M. Babiker
• 4106 · PDF Pan cancer enrichment of homologous recombination repair (HRR) gene alterations in 101,240 tumor samples from AACR Project GENIE: Implications for tumor-agnostic PARP inhibitor expansion Ahmed Abdelhakeem, Nency Ganatra, Dina Elantably, Tayo Adeoye, Nayef H. Abdel-Razeq, Osama M. Mosalem, Hani M. Babiker
• 4107 · PDF Factors associated with early treatment discontinuation in the AACR Project GENIE Biopharma Collaborative (BPC) non-small cell lung cancer (NSCLC) cohort Dany Hamze, Sanjay Mishra, Aleenah Mohsin, Sarah Minuit, Ece Gamsiz Uzun, Jeremy L. Warner
• 4109 · PDF Pan-cancer landscape of IDH1/2 mutations with a focus on non-small cell lung cancer: Insights from the AACR GENIE Registry Zhaohui L. Arter, Cathleen Park, Misako Nagasaka, Sai-Hong I. Ou
• 4110 · PDF Genomic vulnerabilities and clinical behavior of metaplastic breast cancer through integrated registry and GENIE analysis Ahmed Shatta, Diego F. Chamorro, Blessie Elizabeth Nelson, Bora Lim
• 4111 · PDF Comprehensive multi-omics characterization of colorectal cancer in a community catchment population Brigette Waldrup, Francisco Carranza, Yuxin Jin, Yonatan Amzaleg, Mackenzie Postel, David W. Craig, John D. Carpten, Boudoir Salhia, Charite N. Ricker, Julie O. Culver, Carmen E. Chavez, Mariana C. Stern, Lourdes Baezconde-Garbanati, Heinz-Josef Lenz, Enrique I. Velazquez-Villarreal
• 4112 · PDF Identification of NTRK missense mutations in glioblastoma multiforme: Insights from AACR Project GENIE and structural-functional analyses Jehad A. Yasin, Muaath I. Alsufi, Ahmad Shawabkeh, Abdallah Al-Ramadi, Mohammad Alghaniem, Layan AlDaher, Reger Mikaeel
• 4113 · PDF Distinct clinical, molecular and multi-omics biomarkers in early-onset head and neck squamous cell carcinoma Joab O. Odera, Rong Jiang, Morgan C. Byrd, Oyomoare L. Osazuwa-Peters, Nosa Osazuwa-Peters
• 4114 · PDF Population-based patterns of human papillomavirus infections and cervical cancer incidence, driver mutations and overall survival S. Ahmed Hussain, Chunqiao Tian, Christopher Tarney, Thomas Beltran, Pouya Javadian, Ryan McLaughlin, Paulette Mhawech-Fauceglia, Doris M. Benbrook, Sean Cronin, Zachary Kopelman, Colin Sitler, Leslie M. Randall, John Chan, Daniel Kapp, Chad A. Hamilton, Charles A. Leath, Christina Washington, Kathleen Moore, Kristen Bunch, Nicholas Bateman, Thomas P. Conrads, G. Larry Maxwell, Kathleen M. Darcy
• 4116 · PDF Clonal trajectories of chronic lymphocytic leukemia and Richter transformation over the patients' lifespan Ian Márquez-López, Aleix Real, Núria Russiñol, Nicholas Williams, Romina Royo, Markus van Roosmalen, Heribert Playa-Albinyana, Juan Antonio Piñeyroa, Melika Bashiri, Pablo Mozas, Armando López-Guillermo, Julio Delgado, Dolors Colomer, Ruben van Boxtel, Jyoti Nangalia, Elias Campo, Ferran Nadeu

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