In Vitro Models 2: 2D, 3D, Organoids, and Spheroids

• 2497 · PDF 用于个体化选择腹膜癌病化疗途径和方案的人源pcVMT平台 A human pcVMT platform for personalizing chemotherapy route and regimen selection in peritoneal carcinomatosis Aaqil M. Khan, Stephanie J. Hachey, Vinodh Kumar Radhakrishnan, Fatemeh Tajik, Melanie Roman, Christopher C. W. Hughes, Maheswari Senthil
• 4852 · PDF 在早期müllerian癌新模型中解析驱动BRCA1相关转化的分子事件 Unraveling the molecular events driving BRCA1 -associated transformation in novel models of early müllerian cancer Carly A. Tompkins, Victoria R. Cerda, Marcela Haro, Quentin Chartreux, Andrew J. Li, Simon A. Gayther, B.J. Rimel, Fabiola Medeiros, Kate Lawrenson
• 4853 · PDF 全面的子宫内膜癌类器官生物库揭示亚型特异性转录程序和治疗靶点 A comprehensive endometrial cancer organoid biobank reveals subtype-specific transcriptional programs and therapeutic targets Mali Barbi, Shalini Gupta, Santhilal Subhash, Divya Gowthaman, Arielle Katcher, Megan Gorman, Brian Yueh, Erdogan Akyildiz, Uma Mahesh, Devin Gee, Nyasha Chambwe, Charlie Chung, Marina Frimer, Gary L. Goldberg, Semir Beyaz
• 4854 4854 黏液性阑尾癌患者肿瘤类器官的突变谱分析用于临床变量关联及治疗反应标志物研究 Mutational profiling of patient tumor organoids for clinical variable association and markers of therapeutic response in mucinous appendiceal cancers Daniel J. Gironda, Cecilia R. Schaaf, Steven D. Forsythe, R. Andrew Erali, Tiefu Liu, Ming Leung, Ashok K. Pullikuth, Helen R. Bernardirathgeb, Eleftherios Makris, Shay Soker, Edward A. Levine, Konstantinos I. Votanopoulos, Lance D. Miller
• 4855 · PDF 胱硫醚β-合酶驱动卵巢癌的经腹腔转移 Cystathionine beta-synthase drives transcoelomic metastasis in ovarian cancer Pallab Shaw, ARPAN DEY BHOWMIK, Akrit Pran Jaswal, Resham Bhattacharya, Priyabrata Mukherjee, Shailendra Kumar Dhar Dwivedi, Geeta Rao
• 4856 · PDF 在微生理系统中量化抗肿瘤和促肿瘤人中性粒细胞对自然杀伤细胞行为的双重效应 Quantifying the dual effect of anti-tumor and pro-tumor human neutrophils on natural killer cell behaviors in a microphysiological system Shuai Shao, Caroline N. Jones
• 4858 · PDF 在染色体外DNA阳性胃癌中联合泛靶向与精准靶向策略 Combined pan and precision targeting in extrachromosomal DNA-positive gastric cancer Gengyi Zou, Melissa Pizzi, Aryanasingh Bhati, Bansi Vanparia, Wei-Chieh Yu, Ailing Scott, Yibo Fan, Calena Brown-Abel, Liyong Zeng, Johnson Amoah, Tanaya Alexander Washington, Yuan-Hung Lo, Vineet Bafna, Shilpa Dhar, Jaffer Ajani
• 4859 · PDF 一种保留肿瘤微环境以指导个体化免疫治疗的新型肉瘤类肿瘤（tumoroid）平台 A novel sarcoma tumoroid platform preserving the tumor microenvironment to guide personalized immunotherapy Tony Ezzat, Nathaniel Ruppert, Elizabeth Nowak, Danny G. Cho, Masahiro Hitomi, Tyler E. Miller, Gary K. Schwartz, Jacob G. Scott, Zachary D. Burke
• 4860 · PDF 利用患者来源3D生物打印卵巢癌模型预测治疗疗效并揭示肿瘤异质性 Predicting therapy efficacy and revealing tumor heterogeneity using patient-derived 3D bioprinted ovarian cancer models Jiangang Zhang, Huiyu Yang, Ying Shan, Zihan Zhong, Ziren Kong, Yuning Sun, Huayu Yang, Lingya Pan, Yilei Mao, Ying Jin
• 4861 · PDF 利用人胚胎干细胞对IDH突变型低级别星形细胞瘤进行建模 Modeling IDH-mutant low-grade astrocytoma using human embryonic stem cells Greta Henriette Ghita, Yanhong Yang, Viviane Tabar
• 4862 4862 开发一种整合自体成纤维细胞和肿瘤浸润淋巴细胞的高通量多模态患者来源平台用于结直肠癌药物发现 Development of a high-throughput multimodal patient-derived platform integrating autologous fibroblasts and tumor-infiltrating lymphocytes for colorectal cancer drug discovery Lewis Campbell, Agapitos Patakas, Athanasios Koulis, Hannah Findlay, Daria Paruzina, Cameron Fyfe, Ellen Main
• 4863 4863 创新的无异种成分合成水凝胶支持iPSC来源肠道类器官和结直肠癌（CRC）类器官生长——一种用于治疗筛选的先进类器官平台 Innovative xeno free synthetic hydrogel supports iPSC derived intestinal organoids and colorectal cancer (CRC) organoid growth, An advanced organoid platform for therapeutic screening Kalhara R. Menikdiwela, JOHN HUANG
• 4864 · PDF 基于平滑肌定向TP53敲除iPSC的平滑肌肉瘤细胞模型鉴定出新的可干预通路 A leiomyosarcoma cell model based on smooth muscle-committed TP53 -knockout iPSCs identifies novel actionable pathways. Annalisa Astolfi, Livia Gozzellino, Alice Costa, Ilenia Motta, Margherita Nannini, Maria Concetta Nigro, Martina Lops, Maria Giulia Pirini, Antonio De Leo, Gianandrea Pasquinelli, Maria A. Pantaleo
• 4865 · PDF 利用AI驱动的图像分析对患者来源类器官和微类器官球体进行患者药物敏感性的功能评估 Functional assessment of patient drug sensitivity using AI-powered image analysis on patient-derived organoids and micoorganoid spheres Abraham Lin, Maxim Le Compte, Divya L. Dayanidhi, Edgar Cardenas De La Hoz, Rebecca Stone, Tyler Gilcrest, Geert Roeyen, Filip Lardon, Christophe Deben
• 4866 · PDF 结直肠癌细胞与癌相关成纤维细胞在不同促纤维增生反应亚型间的相互作用 Interactions between colorectal cancer cells and cancer-associated fibroblasts across desmoplastic reaction subtypes Wataru Kosaka, Keigo Murakami, Yota Akamori, Hideaki Karasawa, Yuki Yasuda, Ichiro Ise, Tomoyuki Ono, Megumi Murakami, Yoshihiro Sato, Gumpei Yoshimatsu, Hideyuki Suzuki, Takashi Kamei, Shinobu Ohnuma, Toru Furukawa, Michiaki Unno
• 4867 · PDF 放射敏感性指数(RSI):一个用于预测宫颈癌放疗抵抗的患者来源类器官平台 The radiosensitivity index (RSI): A patient-derived organoid platform for predicting radioresistance in cervical cancer Young Joo Lee, Ju Hee Oh, Eun Hye Choi, Kyung Jin Eoh, Sang Wun Kim, Yoo-Na Kim, Ji Hyun Lee, Eun Ji Nam
• 4868 4868 利用患者来源异种移植衍生的三维平台建模胶质母细胞瘤对照射的敏感性 Modelling glioblastoma sensitivity to irradiation with a patient derived xenograft-derived 3D platform Fu-Ju Chou, Annamaria Rapisarda, Marianna Zipeto, Michael Ritchie, Markus Hippich, Daniel Ciznadija, BanuPriya Sridharan, Veena Jagannathan, Gilad Silberberg, Stefano Cairo
• 4870 · PDF 从男性乳腺癌患者来源肿瘤(PDT)中分离、鉴定并建立男性乳腺癌细胞 Isolation, characterization and establishment of male breast cancer cells from male breast cancer patient-derived tumor (PDT) Samikshya Kandel, Kathy Robinson, Ricardo Cosyleon, Daotai Nie, Krishna A. Rao
• 4872 · PDF 新鲜NSCLC的三维生物打印:Lung3Dprint概念验证研究 3D bioprinting of fresh NSCLC: The Lung3Dprint proof of concept study Aurélie Cadiou, Clarisse Thiollier-Schmitt, Gabrielle Devret, Raphaële Guelminger, Tanguy Fenouil, Corinne Perrin, Camille Leonce, Samantha Ballesta, Gaëtan Pochon, Nicolas Alcala, Lars Petter Jordheim, Charles Dumontet, Michaël Duruisseaux
• 4873 4873 在iPSC来源的肺泡肺癌类器官中重建耐药持留(DTP)微环境,用于细胞-细胞相互作用和配体-受体靶点的时空解析 Reconstructing drug-tolerant persister (DTP) niches in iPSC-derived alveolar lung cancer organoids for spatio-temporal dissection of cell-cell interactions and ligand-receptor targets Toshio Suzuki, Harry Choi, Erik Johansson, Tetsuharu Nagamoto, Ayako Suzuki, Takuji Suzuki, Katsuya Tsuchihara, Yutaka Suzuki, Yuki Yamamoto
• 4874 · PDF 利用肿瘤和胃肠道类器官模型对HER2 CAR-T细胞进行临床前评估以界定治疗窗 Preclinical assessment of HER2 CAR-T cells using tumor and GI organoid models to define therapeutic window Julia B. Schueler, Ina Rohleff, Tania Martianez Canales, Kanstantsin Lashuk, Youri von Elsswilk, Namrata Jayanth, Ludovico Buti
• 4876 · PDF 细胞因子补充以改善肿瘤类器官-免疫细胞共培养 Cytokine supplementation for improved tumoroid-immune cell co-culture Shyanne Salen, Colin D. Paul, Sydney Hawkins, Matthew R. Dallas, David Kuninger
• 4877 · PDF 用于评估免疫检查点抑制剂的高通量3D肿瘤-免疫共培养平台 A high-throughput 3D tumor-immune co-culture platform for evaluating immune checkpoint inhibitors Laure-Anne Ligeon, Tabea Gamma, Zuzanna Kotkowska, Charlotte Veser, Irina Agarkova, Sue Grepper, Madhu Nag-LAL
• 4878 · PDF 利用高通量球体微阵列平台模拟NSCLC中肿瘤微环境介导的耐药 Modeling tumor microenvironment-mediated resistance in NSCLC using a high-throughput spheroid microarray platform Alireza Rahnama, Maddalena Arrighi, Ines Pulido Endrino, Takeshi Shimamura, Ian Papautsky
• 4879 · PDF 膀胱癌类器官作为模拟疾病生物学和评估新疗法的转化模型 Bladder cancer organoids as a translational models to model disease biology and assess new therapies Emilie Decaup, Céline Rouget, Amandine Prioux-Quartier, Claire Béraud, Nadège Bidan, Xavier Gamé, Philippe Lluel
• 4880 · PDF 宫颈癌的体外血管化微肿瘤模型 An in-vitro vascularized micro-tumor model of cervical cancer Daniela Gaebler, Christopher C. W. Hughes, Stephanie J. Hachey
• 4881 4881 用于体外模拟聚焦超声破坏血脑屏障（BBB）的回声微泡的制备与表征 Fabrication and characterization of echogenic microbubbles for in vitro modeling of blood-brain barrier (BBB) disruption via focused ultrasound Nathan Han, Nabhan Fakrudin, Frederic Zenhausern, Jian Gu

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