PO.TB10.19 · 肿瘤生物学
Tumor-Immune Crosstalk
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4976 · PDF 一种B7家族蛋白的上调驱动治疗诱导的衰老癌细胞发生免疫逃逸 Upregulation of a B7 family protein drives immune escape in therapy-induced senescent cancer cells Donghee Kang, Min-Ji Kim, Hyung Jung Hwang, Jeong Minwoo, Jong-Ho Cha, Jae-Seon Lee
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4977 · PDF 程序性细胞死亡配体1(PD-L1)在人乳腺高级别导管原位癌(DCIS)各分子亚型中的表达 Programmed cell death ligand 1 (PD-L1) expression across molecular subtypes of human high-grade ductal carcinoma in situ (DCIS) of the breast Hossein Schandiz, Lorant Farkas, Berit Gravdehaug, Elin Edda Seland Agustsdottir, Torill Sauer, Jürgen Geisler
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4978 · PDF 化疗初治三阴性乳腺癌中MHC I类表达及多种免疫细胞的分布:抗原提呈的缺失可带来高TILs和良好预后,可能通过调节性T细胞构成的减少实现 MHC class 1 expression and distribution of multiple immune cells in chemotherapy-naïve triple-negative breast cancers: lack of antigen-presentation can bring high TILs and good prognosis, possibly via decreased regulatory T-cell composition Makiko Yamashita, Akira I. Hida, Naomi Gondo, Yasuyo Ohi, Shigehisa Kitano
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4979 · PDF CD155结合肽增强T细胞的抗肿瘤活性及溶解肽在结肠肿瘤中的细胞毒性活性 CD155- binding peptide enhances antitumor activity of T cells and cytotoxic activity of a lytic peptide in colon tumor Gunassekaran Gowri Rangaswamy, Poongkavithai Vadevoo Sri Murugan, Byungheon Lee
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4980 · PDF 胸膜间皮瘤中CD163阳性肿瘤相关巨噬细胞空间分布的临床与预后意义 Clinical and prognostic significance of spatial distribution of CD163-positive tumor-associated macrophages in pleural mesothelioma Ryota Sumitomo, Tetsuya Fukui, Masashi Kobayashi, Hiroaki Sakai, Toshi Menju
- 4981 4981 肝癌免疫治疗的新思路与新策略 New thought and strategy of liver cancer immunotherapy Gen-Sheng Feng
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4982 · PDF 靶向胶原受体CD49b通过促进乳腺癌中CD8⁺ T细胞免疫增强PD-L1阻断疗效 Targeting collagen receptor CD49b enhances PD-L1 blockade by promoting CD8⁺ T-cell immunity in breast cancer Ibrahim R. Eissa, Kenneth K. Tanabe
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4984 · PDF 解离、空间和功能性单细胞分析揭示HPV阴性HNSCC中肿瘤反应性T细胞的抗原驱动性耗竭和趋化失败 Dissociative, spatial, and functional single-cell profiling reveals antigen-driven exhaustion and chemotactic failure of tumor-reactive T cells in HPV-negative HNSCC Joseph Zenga, Musaddiq Awan, Fumou Sun, Stuart J. Wong, Abdullah Memon, Tyce Kearl, Ean Norenberg, Margaret L. Hoang, Joseph M. Beechem, Eric Hobbs, Ashley Heck, Rachel Liu, Daniel McGuire, Erin Piazza, Peiman Hematti, Heather Himburg
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4985 · PDF CD5L在调控肝脏免疫细胞中的作用 The role of CD5L in regulating liver immune cells Diala S. Alhousari, Handan Hong, Taojian Tu, Bangyan L. Stiles
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4986 · PDF 鉴定三阴性乳腺癌中高淋巴细胞浸润的肿瘤微环境 Identification of tumor microenvironment for high infiltration of lymphocytes in triple negative breast cancer Sowon Choi, Hee Jin Lee, Byung-Kwan Jeong, Hyun Je Kim
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4987 · PDF JNK1和JNK2在TNBC进展和肿瘤微环境免疫调节中的双重作用揭示了一种新的治疗脆弱性 Dual roles of JNK1 and JNK2 in TNBC progression and tumor microenvironment immune modulation reveal a novel therapeutic vulnerability Bharat Singh Kuntal, Xuemei Xie, Xanthe stern, Kendall Nakaoka, Marilisa Fujimoto, Marisa William, Madixx Muramoto, Naoto T. Ueno
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4988 · PDF 全面的肿瘤微环境分析鉴定出干性高的肝细胞癌中的抑制性免疫格局 Comprehensive tumor microenvironment analysis identifies a suppressive immune landscape in stemness-high hepatocellular carcinoma Woo Young Kwon, Sungho Ko, Sungwoo Cho, Song-A Park, Sihun Cho, Sung Hwan Lee
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4990 · PDF 单细胞质谱流式揭示无组织学可检测转移的ER+乳腺癌前哨淋巴结中的T细胞耗竭 Single-cell mass cytometry reveals T-cell exhaustion in sentinel nodes of ER+ breast cancer without histological detectable metastases Inga Hansine Rye, Marit Otterlei FJørtoft, Karin Teien Lande, Margit Riis, Ole Christian lingjærde, Øystein Garred, Colin LaMont, June Myklebust, Kanutte Huse, Hege Russnes
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4991 · PDF 基质MAOB通过抑制抗肿瘤免疫促进前列腺癌生长 Stromal MAOB promotes prostate cancer growth by suppressing antitumor immunity Jing Wei, Hsiang Ching Huang, Kaisheng Yuan, Alivia O'Brien, Boyang Wu
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4992 · PDF Activin A 通过免疫抑制和非经典信号通路促进 PDAC 进展 Activin A promotes PDAC progression via immunosuppression and non-canonical signaling Mark B. Wiley, Jessica Bauer, Yuchen Wang, Barbara Jung
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4993 · PDF 肿瘤相关巨噬细胞促进口腔鳞状细胞癌的发生 Tumor-associated macrophages promote oral squamous cell carcinoma development Manlin Shao, Carlos Caulin
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4994 · PDF 外泌体靶向 xmot-shRNA 作为一个模块化平台,用于剖析驱动肿瘤微环境中致耐受性树突状细胞的信号通路 Exosome-targeted xmot-shRNA as a modular platform to dissect signaling pathways driving tolerogenic dendritic cells in the tumor microenvironment Mahere Rezazade Bazaz, Michael P. Plebanek, Y-Van Nguyen, Xueying Wang, Balamayooran Theivanthiran, Brent A. Hanks
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4995 · PDF LAMP3+ 迁移性树突状细胞在非霍奇金淋巴瘤中建立免疫可及的肿瘤微环境 LAMP3+ migratory dendritic cells establish immune-accessible tumor microenvironment in non-Hodgkin lymphoma Yulong Wei, David Alexander Braun, Ya-Chi Ho
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4996 · PDF 肾细胞癌中生物标志物的发现与肿瘤免疫抑制的靶向 Biomarker discovery and the targeting of tumor immune suppression in Renal Cell Carcinoma Giuliana P. Mognol, Erpei Wang, William Harris, Tami Von Schalscha, Birkley S. Lim, Rayan Jouny, Ahmed Abdelhak, Rana R. McKay, Judith Varner
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4997 · PDF 疑似前列腺癌哥伦比亚男性的 TME 分析 TME profiling in Colombian men with suspected prostate cancer Dayanne M. Rodríguez Hernández, Jovanny Zabaleta, Luis D Valle, Rafael Parra-Medina, Carmen L. Roa, Alvaro Gutierrez, Mateo Barros Barraza, Alba Lucía Cómbita
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4998 · PDF 人肿瘤相关巨噬细胞的 ImmunoPET 成像 ImmunoPET imaging of human tumor associated macrophages Ayla Vaughn Embs, Borna Roohani, Robin Kumar, Dajah Nash, Chloe La Prairie, Mann Dangarwala, Harriet M. Kluger, Ping Zhang, Benjamin Larimer, Bernadette V. Marquez-Nostra
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4999 · PDF GFRAL 并非 PDAC 肿瘤发生和 TME 免疫细胞抑制所必需 GFRAL is not required for PDAC tumor development and TME immune cell suppression Emma Crockett Funk, Abasi-ama Udeme, Cynthia F. Wright, Jenna Schwesig, Michael C. Ostrowski, Teresa A. Zimmers, Leonidas G. Koniaris, David Wang, Denis C. Guttridge
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5000 · PDF 激活素受体亚型2A调控胰腺癌细胞中固有免疫细胞活化及非经典信号通路 Activin receptor subtype-2A regulates innate immune cell activation and non-canonical signaling in pancreatic cancer cells Yuchen Wang, Mark B. Wiley, Jessica Bauer, Xinru Wang, Jordi Guillem-Marti, David Lee, David Baker, Barbara Jung
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5001 · PDF 利用PWK × NeuT小鼠研究HER2驱动的MHC I类免疫逃逸动态 Dynamics of HER2-driven MHC I immune evasion utilizing PWK x NeuT mice Ryann Ray, Hui-En Chou, WEI-ZEN WEI, Jennifer Jacob
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5002 · PDF Notch4阻断重编程肿瘤相关巨噬细胞并增强乳腺癌中的抗肿瘤炎症特征 Notch4 blockade reprograms tumor-associated macrophages and enhances anti-tumor inflammatory signature in breast cancer Katherine A. Alexander, Jason Eng, Yu Kato, Bhairavi Swaminathan, Debdutta Mandal, Yajath Narra, L. A. Naiche, Yasuhiro Funahashi, Junji Matsui, Jan Kitajewski
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5003 · PDF Treg特异性抑制hedgehog信号改变其功能并阻碍小鼠三阴性乳腺癌的生长 Treg-specific inhibition of hedgehog signaling alters their function and impedes the growth of murine triple-negative breast cancer Ian Miranda, Courtney Swain, Brandon J. Metge, Lalita Shevde