Cell Death Pathways and Treatment

• 5663 5663 化疗诱导的galectin-1在三阴性乳腺癌中衍生出与EMT相关的耐药持留状态，并对铁死亡诱导剂具有可靶向的脆弱性 Chemotherapy-induced galectin-1 derives drug-tolerant persister state associated EMT in triple negative breast cancer with targetable vulnerability to ferroptosis inducers Shagufa A. Ehtesham Shaikh, Kedar Sharma, Dipti Bhattacharya, Vaibhav Kothari, Samruddhi Jadhav, Nandini Verma
• 5664 · PDF 利用诱导铁死亡的siRNA纳米疗法靶向胆管癌 Targeting cholangiocarcinoma with ferroptosis-inducing siRNA-based nanotherapeutics Peyton Classon, Danielle Marie Carlson, Jayla Millender, Irene Yan, Sumera Ilyas, Rory L. Smoot, TUSHAR PATEL, Gregory J. Gores, Davide Povero
• 5665 · PDF 藁本内酯A通过抑制GPX4表达并激活铁死亡来抑制膀胱癌进展 Levistolide A inhibits bladder cancer progression by suppressing GPX4 expression and activating ferroptosis Yixi Gong, Jihye Kim, Ingyu Lee, Xiaoyu Guo, Bomi Han, Eui Man Jeong
• 5666 · PDF Tambiciclib（SLS009）是一种CDK9抑制剂，在AML细胞系中促进凋亡并抑制MCL-1水平 Tambiciclib (SLS009), a CDK9 inhibitor, promotes apoptosis and suppresses MCL-1 levels in AML cell lines Elizabeth C. Trull, Philip C. Amrein
• 5667 · PDF 铁死亡在卵巢癌中需要caspase-5依赖的GSDME切割 Ferroptosis necessitates caspase 5 dependent GSDME cleavage in ovarian cancer Mahmuda Akter, Lei Sun, Cheng Chi, Shuang Huang
• 5668 · PDF USP7和ITCH/UBE4B泛素连接酶通过Ku70和c-FLIPL多聚泛素化调控神经母细胞瘤中凋亡与坏死性凋亡之间的转换 USP7 and ITCH/UBE4B ubiquitin ligase regulate the switch between apoptosis and necroptosis via Ku70 and c-FLIPL polyubiquitination in neuroblastoma Christophe Le Clorennec, Carla Sampaio, Peter E. Zage
• 5669 · PDF 探究TRPM4在ErSO及其衍生物诱导的癌细胞死亡中的作用 Investigating the role of TRPM4 in the cancer cell death induced by ErSO and derivatives Brooke A. Bouwens, Michael P. Mulligan, Rowan Glover, Paul J. Hergenrother
• 5670 · PDF 氧化应激介导的非凋亡、非自噬性细胞死亡：一种在机制上独特的克服结直肠癌细胞耐药策略 Oxidative stress-mediated non-apoptotic, non-autophagic cell death: A mechanistically distinct strategy to overcome resistance in colorectal cancer cells Mati Ur Rehman, Almuayyad Gajani, Mahwish Fatima, Paras Jawaid, Arooj Shafiq, Azhar Hussain Rajabali
• 5671 · PDF 携带DSB进入有丝分裂通过53BP1介导的NLRP3炎症小体激活诱导焦亡 Mitotic entry with DSB induces pyroptosis through 53BP1-mediated NLRP3 inflammasome activation Mengshi Luo, Yuewen Zhang, Wenjian Gong, Zhiqi Liao, Linghui Wang, Qiuyang Xu, Xingzhe Liu, Yijie Wu, Xuejiao Zhao, Gorden B. Mills, Ding Ma, Guangnian Zhao, Qinglei Gao, Yong Fang
• 5672 · PDF PRMT5抑制增强胶质母细胞瘤对Bcl-xL/Bcl-2抑制剂的治疗易感性 PRMT5 inhibition enhances therapeutic vulnerability to Bcl-xL/Bcl-2 inhibitors in glioblastoma Shumpei Onishi, Ashis Chowdhury, Jean-Paul Bryant, Dragan Maric, Qi Li, Jing Wu, Yeshavanth Kumar Banasavadi-Siddegowda
• 5673 · PDF 铁死亡诱导与KRAS抑制剂在KRAS突变型肺腺癌中产生协同作用 Ferroptosis induction synergizes with KRAS inhibitors in KRAS -mutant lung adenocarcinoma Amirali Karimi, Yu Qian, David Molkentine, Alvaro Guimaraes Paula, Busra Ernhofer, David Hwa Peng, Monique B. Nilsson, John V. Heymach
• 5674 · PDF CD47阻断诱导坏死性凋亡并与BCL-2抑制在血液系统恶性肿瘤中互补 CD47 blockade induces necroptosis and complements the effects of BCL-2 inhibition in hematologic malignancies Stephen Jun Fei Chong, Rebecca Valentin, Jing Wang, Fen Zhu, Filip Garbicz, Kartini Iskandar, Brienne C. Y. Toh, Marisa Peluso, Jeremy Zhang, Liam Hackett, Benjamin H. Lee, Li Ren Kong, Catherine J. Wu, Wee Joo Chng, Shazib Pervaiz, Carsten U. Niemann, Ruben D. Carrasco, Matthew S. Davids
• 5675 · PDF MUC1-C靶向exatecan ADC在转移性结直肠癌中诱导基因毒性应激并转录性抑制UPR-炎症通路 MUC1-C-directed exatecan ADC induces genotoxic stress and transcriptional suppression of UPR-inflammatory pathways in metastatic colorectal cancer Surender Kharbanda, Deepak Raina, Rehan Ahmad, Changchuin Mao, Sourav Choudhary, Brian Lawney, Nandita Sreenivasalu, Govind Panchamoorthy, Ravi Jasuja
• 5676 · PDF 致命的啃咬：理解巨噬细胞介导的胞啃作用后癌细胞的命运 Bites that kill: Understanding cancer cell fate after macrophage mediated trogocytosis Ishwaree Datta, Meghan Morrissey, Annie Rogers
• 5677 · PDF GPX4-FTH1-ARNT信号调控铁外排以抑制铁死亡性细胞死亡并促进骨肉瘤中的免疫重塑 GPX4-FTH1-ARNT signaling regulates iron efflux to suppress ferroptotic cell death and promote immune remodeling in osteosarcoma Md Abdullah, Donghee Lee, Jong Hyuk Kim
• 5678 · PDF 在TP53突变型急性髓系白血病中诱导铜死亡 Cuproptosis induction in TP53-mutated acute myeloid leukemia Yuju An, Xinghan Zeng, Brandy Perkins, Nour S. Naji, Yanyan Wang, Booseong Seo, Yashvi Hemani, Frederick Bunz, Theodoros Karantanos
• 5679 · PDF 用EC359抑制LIFR触发铁死亡以克服子宫内膜癌的化疗耐药 LIFR inhibition with EC359 triggers ferroptosis to overcome chemoresistance in endometrial cancer Emily Jean Aller, Baskaran Subramani, Xue Yang, Paulina Ramirez, Bindu Santhamma, Hareesh B. Nair, Edward Kost, Ratna K. Vadlamudi, Suryavathi Viswanadhapalli
• 5680 5680 Hinokitiol靶向肝癌的金属与氧化还原易感性 Hinokitiol targets metal and redox vulnerabilities in liver cancer Daniela Delgado, Anyssa Rodriguez, Subhash C. Chauhan, Nirakar Sahoo
• 5681 · PDF 线粒体非依赖性铜死亡（cuproptosis）的机制 Mechanism of mitochondria-independent cuproptosis Martin Mistrik, Martin Loffelmann, Petr Dzubak, Marian Hajduch, Josef Srovnal, Zdenek Skrott, Lucie Beresova, Tomas Pluhacek, Petr Tarkowski
• 5682 · PDF 阐明并克服食管腺癌的治疗耐药性 Elucidating and overcoming therapeutic resistance in esophageal adenocarcinoma Naren Li, Jessica Ji, Jaylon C. Aggison, Siqi Wu, Francisco A. Molina-Pelayo, Cristian G. Medina, Ritika Raj, Yuan Xu, Robert T. Ripley

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