PO.IM02.06 · 免疫学
Oncogenic Pathways and Cancer Immunity
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5558 · PDF KRT6A mediates immune exclusion and anti-PD-1 resistance in head and neck squamous cell carcinoma Yi-Che Wu, Muh-Hwa Yang
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5559 · PDF Spatial neuroimmune crosstalk driving perineural invasion in head and neck squamous cell carcinoma Riya Chhabra, Alfred Kao, Suravi Bajaj, Reena Ding, Daniel John, Wei Tse Li, Jessica Y. Wang-Rodriguez, Weg M. Ongkeko
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5560 · PDF KRAS G12D inhibition stimulates antigen presentation and potentiates mRNA-based immunotherapy in pancreatic cancer Amanda Creech, Hailey Lee, Khalid Rashid, Tony Luu, Emma Lieberman, Michael Srienc, Alykhan Premji, Ahmad Kassem, Luyi Li, James Wohlschlegel, Timothy Donahue, Norbert Pardi, Caius Radu
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5561 · PDF LILRB1 antibody targeting the LILRB1/HLA-G axis: Preclinical efficacy, pharmacokinetics, and safety supporting first-in-human trials Han Byoul Kim, Seok-Joo Kim, Younghoon Kim, Junhaeng Cho, Minsoon Kim, JungA Kim, Suji Hong, Heehang Kim, Shin-Young Kang, Kyungna Ko, Jun-Gyu Park, Hyungjin Cho, Jeeyeon Roh, Young Dok Son, Wooseok Ko
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5562 · PDF Antagonism of beta-Catenin/BCL9 interaction suppresses polymorphonuclear myeloid-derived suppressor cell generation and maintenance Claudio Scuoppo, Julia Diehl, Rick Ramirez, Barry J. Kappel, Abi Vainstein-Haras, Jim A. Rotolo
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5563 · PDF Long noncoding RNAs networks as novel master regulators of cytotoxic immune cell exhaustion in triple-negative breast cancer Raquel Sanchez, Eduardo E. Chaib Lozano, Barbara Yang, Shrikanth S. Gadad, Enrique I. Ramos
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5564 · PDF Crosstalk between ceramide and prostaglandin signaling mediates resistance to immune checkpoint blockade Wyatt O. Wofford, Elif Percin, Han G. Lee, Odai Darawshi, Bryan Granger, Lucy Mulligan, Natalia V. Oleinik, Mohamed F. Kassir, Chase Walton, Paramita Chakraborty, Stefano Berto, Raymond N. DuBois, Shikhar Mehrotra, Besim Ogretmen
- 5565 5565 C118S-mediated redox modulation of KRASG12D mutation reprograms immunometabolism to suppress obesity-driven pancreatic tumorigenesis Zahid Rafiq, Weiqin Lu
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5566 · PDF Molecular evolution reveals low-prevalence driver mutations, mutational synergies, and associated immune dynamics in ovarian cancer Julia McAdams, Nic Fisk
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5567 · PDF Combination therapies promote immune-mediated bystander killing of KRAS-G12C inhibitor resistant cells Mona Tomaschko, KangBo Ng, Christopher Moore, Claire E. Pillsbury, Sareena Rana, James Campbell, Saptaparna Mukherjee, Ania Mikolajczak, Panayiotis Anastasiou, Andrea de Castro, Alicia Alonso de la Vega, Sophie de Carné Trécesson, Nathan W. Goehring, Miriam Molina-Arcas, Julian Downward
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5568 · PDF PRTN3 suppresses cytotoxic immune-cell activation and antitumoral immunity through proteolytic cleavage of CXCL9 in KRAS mutant lung adenocarcinoma Rong Xiang, Yi Liu, Yunping Luo
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5570 · PDF Multi-omics dissection of tumor-related leukocytosis in urothelial carcinoma identifies IL13RA2 as a key driver Harvey Yu-Li Su, Shih-Yu Huang, Chung-Wen Kuo, Chang-Ting Lin, Yi-Hua Chen, Ming-Chun Kuo, Hsuan-Ying Huang, Chih-Yen Chien
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5571 · PDF Dynamic transcriptional remodeling and functional adaptation drive malignant progression in lymphoma Bandish Kapadia, Anirban Roychodhury, Forum Kayastha, Won Sok Lee, Nahid Nanaji, Jolene windle, Ronald B. Gartenhaus
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5572 · PDF Conservation of driver mutations and oncogenic pathway alterations revealed through a comparative genomic analysis of human angiosarcoma and canine hemangiosarcoma Lucas Rodrigues, Garrett Harvey, Gerald Post, Benjamin Lewis, Abigail Hull, Aubrey O'Grady, Lindsay Lambert, Christina Lopes, Thaddeus Allen
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5573 · PDF Novel ASPORIN/CRABP2 axis drives cell-state plasticity from adenocarcinoma to neuroendocrine-like prostate cancer Parthasarathy Seshacharyulu, Shobhit Lall, Sushanta Halder, Sakthivel Muniyan, Zahraa Wajih Alsafwani, Ramakanth Chirravuri-Venkata, Moorthy P. Ponnusamy, Surinder K. Batra
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5574 · PDF Role of KMT2C and KMT2D in modulating tumor immune microenvironment of endometrial cancer Sanjeev Ganesh, Swornalata Pukhrambam, Juveria Ali, Savannah Hughes, Heather Marie Gibson, Michael Wilson
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5575 · PDF Inhibition of immune evasion via targeting the dysregulated EZH2-RKIP axis in cancer cells Ryan McWhorter, Talia Festekedjian, Benjamin Bonavida
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5576 · PDF BRD- and EHMT-dependent immunosuppressive transcriptome in triple-mutant Astrocytoma Qingzhu Gao, Leyi Xie, Gengchen Cai, Sophie Sall, Bachchu Lal, Lopez-Bertoni Hernando, John Laterra, Yunqing Li
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5577 · PDF LSD1 inhibition remodels the tumor microenvironment to enhance anti-PD1 immunotherapy in HNSCC Amit Kumar Chakraborty, Chumki Choudhury, Rajnikant Raut, Manish V. Bais
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5578 · PDF Regulation and expression of transposable elements in ovarian cancer Reddick Russell Walker, Kevin Nestler, Melissa Hadley, Katherine B. Chiappinelli