Senescence and Cell Stress

• 6000 · PDF 转谷氨酰胺酶2介导p53依赖性衰老相关分泌表型 Transglutaminase 2 mediates the p53-dependent senescence-associated secretory phenotype Xiaoyu Guo, Jihye Kim, Yi-Xi Gong, Ingyu Lee, Bomi Han, Ki Baek Lee, In-Gyu Kim, Eui Man Jeong
• 6001 · PDF 衰老抑制性Δ133p53alpha减轻小鼠的加速衰老 Senescence-inhibitory Δ133p53alpha mitigates accelerated ageing in mice Leo Yamada, Huaitian Liu, Natalia Von Muhlinen, Curtis C. Harris, Izumi Horikawa
• 6002 · PDF lncRNA TUG1通过RNA-蛋白相互作用增强解旋酶介导的R-loop解离 The lncRNA TUG1 enhances helicase-mediated R-loop resolution through RNA-protein interaction Shuya Mimura, Jingqi Xie, Miho M. Suzuki, Yutaka Kondo
• 6003 · PDF JAK抑制剂对黑色素瘤细胞中细胞因子诱导性衰老的调控：一种提高免疫检查点抑制剂疗效的可能途径 Modulation of cytokine-induced senescence in melanoma cells by JAK inhibitor: A possible way to improve therapeutic efficacy of immune checkpoint inhibitor Min You, Niramol Savaraj, Ying-Ying Li, Chunjing Wu, Mano Nagarajan, Medhi Wangpaichitr, Lynn G. Feun
• 6004 · PDF 核膜蛋白LEM2与内质网应激信号通路之间的联系为肿瘤发展特征提供新见解 A link between the nuclear envelope protein LEM2 and an endoplasmic reticulum stress signaling pathway provides new insight into features of tumor development Natasha O. Saik, Maho Niwa, Katharine S. Ullman
• 6005 · PDF 人类DEAH盒RNA解旋酶8调控HSF1介导的应激反应和癌症相关的前体mRNA剪接 Human DEAH-box RNA helicase 8 regulates HSF1-mediated stress response and cancer-associated pre-mRNA splicing Jennifer R. Tall, Robert Te Poele, Alexandra Vasile, Pradeep Ramagiri, Caitlin Davies, Marissa Powers, Toby Roe, Deivendran Sankaran, Konstantinos Mitsopoulos, Bissan Al-Lazikani, Robert L. Van Montfort, Emmanuel de Billy, Paul Workman, Paul A. Clarke
• 6006 · PDF 核内p62-PI4,5P2共定位的发现提示癌症蛋白质稳态中一个新的调控层次 Discovery of nuclear p62-PI4,5P 2 colocalization suggests a new regulatory layer in cancer proteostasis Alexandra Gebbia, Oisun Jung, Suyong Choi
• 6007 · PDF 成纤维细胞驱动的IGF1信号在结直肠癌浸润前沿抑制CD44并促进肿瘤细胞衰老 Fibroblast-driven IGF1 signaling suppresses CD44 and promotes tumor cell senescence at the invasive front of colorectal cancer Tae Jun Park, Hee Young Kang, Jang Hee Kim, Seok Yun Kang, Hyun Woo Lee, Sang Wun Kim, Hong Seok Kim, Soon Sang Park
• 6008 · PDF 将PON2定义为肺腺癌中铁氧化还原平衡与铁死亡防御的代谢性免疫检查点 Defining PON2 as a metabolic immune checkpoint of iron redox balance and ferroptotic defense in lung adenocarcinoma Yonatan Amzaleg, Angel Perez-Hunt, Chi Li, Aaron M. Neely
• 6009 · PDF 线粒体谷胱甘肽还原酶作为KEAP1/NRF2突变型非小细胞肺癌的氧化还原易损性 Mitochondrial glutathione reductase as a redox vulnerability in KEAP1/NRF2-mutant non-small cell lung cancer Yun Huang, Chao Ting, Jing-Chun Lin, Ryan Martin, Duy T. Nguyen, Jose Serrano-Velez, Yun Pyo Kang, Nathan P. Ward, Ana P. Da Silva Gomes, Mingxiang Teng, Chang Jiang
• 6010 · PDF 癌症微环境中的细胞衰老 Cellular senescence in the cancer microenvironment Subhiksha Meenakshisundaram, Robyn Laura Kosinsky, Dominik Saul
• 6011 · PDF 转移性结直肠腺癌中治疗诱导的衰老：对单细胞生物学和治疗性干预的意义 Treatment-induced senescence in metastatic colorectal adenocarcinomas: implications for single-cell biology and therapeutic intervention Antoine Hollebecque, Marine Aglave, Mohamed-Amine Bani, Trang Nguyen, Ludovic Bigot, Thierry Mathieu, Florence Lhospice, Benjamin Le Calvé, Eric Angevin
• 6013 · PDF TUSC2驱动NK细胞成熟及衰老相关的功能衰退 TUSC2 drives NK cell maturation and aging-associated functional decline Salvador Gonzalez Ochoa, Metin Aksu, Karan Lagisetty, Edward J. Hughes, Thanigaivelan Kanagasabai, Muna A. Mohammed, Alla Ivanova, Anil Shanker
• 6014 · PDF 从金属到恶性：ROS和炎症细胞因子如何加速镉诱导的前列腺癌变 From metal to malignancy: How ROS and inflammatory cytokines accelerate cadmium-induced prostate carcinogenesis Kunj Bihari Gupta, Truett Taylor, Siva S. Panda, Vinata B. Lokeshwar, Bal L. Lokeshwar
• 6015 · PDF 衰老相关分泌表型驱动PGCC的生命周期和卵裂球样重编程以促进治疗抵抗 Senescence-associated secretory phenotype ​drives PGCC‘s lifecycles and blastomere-like reprogramming to promote therapeutic resistance Zhiqian Zhang, Xiaoran Li, Xinxin Tian, Limin Deng, Jin-Tang Dong, Jinsong Liu
• 6016 · PDF 从天然资源中鉴定一种靶向癌基因诱导性和DNA损伤诱导性衰老的新型非黄酮类衰老裂解剂 Identification of a novel non-flavonoid senolytic agent from natural resources targeting oncogene- and DNA damage-induced senescence Jihye Kim, Xiaoyu Guo, Yi-Xi Gong, Ingyu Lee, Bomi Han, Eui Man Jeong
• 6017 · PDF BET抑制通过上调TXNIP增强骨肉瘤对挽救性化疗的反应 BET inhibition potentiates salvage chemotherapy response through TXNIP upregulation in osteosarcoma Keiko E. Kreklau, Niknam Riyahi, Ryli E. Justice, M. Reza Saadatzadeh, Erika A. Dobrota, Harlan E. Shannon, Rada Malko, Christopher Davis, Khadijeh Bijangi-Vishehsaraei, Sara Covin, Melissa A. Trowbridge, Kathy Coy, Felicia M. Kennedy, Anthony L. Sinn, Christopher D. Collier, Steven P. Angus, Karen E. Pollok, Pankita H. Pandya
• 6018 · PDF 活性氧(ROS)敏感的SOX4信号通路介导食管腺癌的铁死亡 Reactive oxygen species (ROS)-sensitive SOX4 signaling mediates ferroptosis in esophageal adenocarcinoma Heng Lu, Farah Ballout, Dunfa Peng, Lei Chen, Zheng Chen, Wael El-Rifai
• 6019 · PDF 脂肪酸暴露促进具有促肿瘤发生潜能的年龄相关性乳腺组织改变 Fatty acid exposure promotes age-related mammary tissue alterations with pro-tumorigenic potential Mariana Bustamante Eduardo, Abul B.M.M.K. Islam, Curtis W. McCloskey, Maria Paula Zappia, Ashok Z. Samuel, Maxim V. Frolov, Rama Khokha, Rohit Bhargava, Elizaveta V. Benevolenskaya, Seema A. Khan, Susan E. Clare
• 6020 · PDF 衰老性胶质母细胞瘤细胞外囊泡的货物分析鉴定小核仁RNA作为治疗诱导性衰老的候选液体生物标志物 Cargo profiling of extracellular vesicles from senescent glioblastoma identifies small nucleolar RNAs as candidate liquid biomarkers for therapy-induced senescence Valerie DeLuca, Nathaniel Hansen, Priya Digumarti, Nanyun Tang, Karen Fink, George J. Snipes, Patrick Pirrotte, Michael E. Berens

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