PO.MCB07.03 · 分子与细胞生物学
Mechanisms and Dynamics of Gene Expression
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5946 · PDF 鸟苷素基因位点的蛋白质组学揭示了结直肠癌中GUCY2C激素沉默背后的Wnt/beta-catenin调控因子 Proteomics at the guanylin gene locus reveals Wnt/beta-catenin regulatory factors underlying GUCY2C hormone silencing in colorectal cancer Adi Caspi, Ariana A. Entezari, Jasmine R. Alvarez, Annie K. Londregan, Thomas J. M. Kuret, Jeffrey A. Rappaport, Adam E. Snook, Scott A. Waldman
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5947 · PDF LSD1在尤因肉瘤中执行去甲基化酶非依赖性和背景特异性功能 LSD1 performs demethylase-independent and context-specific functions in Ewing sarcoma Rachel D. Dreher, Cenny C. Taslim, Ira Miller, John W. Sherman, Ariunaa Bayanjargal, Emily R. Theisen
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5948 · PDF 唾液腺导管癌中EGR1表达与神经周围侵犯:SDCDN与SDCXPA的比较 EGR1 Expression and Perineural Invasion in Salivary Duct Carcinoma: A comparison of SDCDN and SDCXPA Airi Sakyo, Eijitsu Ryo, Seiichi Yoshimoto, Go Omura, Chihiro Fushimi, Toshihiko Sakai, Yoshifumi Matsumoto, Azusa Sakai, Kohtaro Eguchi, Yo Suzuki, Kazuki Yokoyama, Yoshitaka Honma, Yasushi Yatabe, Fumihiko Matsumoto, Taisuke Mori
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5949 · PDF 靶向SLC25A13通过代谢重编程使黑色素瘤对治疗敏感并降低肿瘤侵袭性 Targeting SLC25A13 sensitizes melanoma to treatment and reduces tumor aggressiveness via metabolic rewiring Beatriz Cristina Biz Tonin, Ana Luísa P. Auyb, Jérémie Nsengimana, Hátylas Azevedo, Beatriz Kopel, Nadja C. Souza-Pinto, Frank John Slack, Miriam G. Jasiulionis
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5950 · PDF PAX3::FOXO1的动态低复杂度结构域相互作用介导腺泡状横纹肌肉瘤中内源性病理性转录枢纽的形成 Dynamic low-complexity domain interactions of PAX3::FOXO1 mediate endogenous pathological transcriptional hub formation in alveolar rhabdomyosarcoma Yanghao Zhong, Michael Di Martino, Shasha Chong
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5951 · PDF 肥大性染色质凝聚体调控癌症中的癌基因 Hypertrophic chromatin condensates govern oncogene control in cancer Bjorn Stolte, David Pease, Max Slotnik, Anna Pertl, Nancy Hannett, Tong Ihn Lee, Richard Young
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5952 · PDF 剪接因子突变型癌症中共有剪接异常的统一机制 A unifying mechanism for shared splicing aberrations in splicing factor mutant cancers Rahul Roy, Prajwal C. Boddu, Manoj M. Pillai
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5953 · PDF 通过在时空维度上探索全转录组解锁小鼠研究新前沿——聚焦小鼠胚胎E11–E14期 Unlocking new frontiers in mouse research by exploring the whole-transcriptome in space and time with mouse embryo stages E11 - E14 Michael Patrick, Liang Zhang, Isabel Lee, Shanshan He, Martin Shelton, John Lyssand, Joseph M. Beechem
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5954 · PDF 利用TempO-LINC实现对RNA降解和低起始量样本的单细胞转录组分析 Enabling single-cell transcriptomics from samples with degraded and low-input RNA using TempO-LINC Kevin White, Albus Kilili, Hanna Ha, Dennis Eastburn, Nathan Jayne, Salvatore Camiolo, Zhoutao Chen, Bruce Seligmann
- 5955 5955 通过转录、染色质可及性分析及足迹推断的转录因子活性解析乳腺癌转移中的增强子逻辑 Dissecting the enhancer logic in breast cancer metastasis through transcriptional, chromatin accessibility profiling and footprint-inferred transcription factor activity Frances Heredia Negron, Homer W. Fogle, Michael R. Kelly, Kamila Wisniewska, Lisa A. Carey, Hector L. Franco
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5956 · PDF 进化选择的安第斯Aymara人NFKB1多态性对子宫内膜癌和卵巢癌中炎症性及HIF依赖性基因表达的影响 Effect of the evolutionary selected Andean Aymara NFKB1 polymorphisms on inflammatory and HIF-dependent gene expression in endometrial and ovarian cancer Jihyun Song, Soo Jin Kim, Anthony Panarelli, Linus Chuang, David Doo, Leslie Andriani, Shatovisha Dey, Syeda Rashid, Steven Sieber, Sabina I. Swierczek
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5957 · PDF 肿瘤性转化中的转录改变 Transcriptional alterations in neoplastic transformation Usman Hyder, Nova Fong, Benjamin Erickson, David Bentley
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5958 · PDF APOBEC4——p53依赖性肿瘤抑制的新型调控因子 APOBEC4, a novel regulator of p53-dependent tumor suppression Dipesh Thapa, Atul Ranjan, Alejandro Parrales Briones, Elizabeth Thoenen, Shigeto Nishikawa, Jay Vivian, Tomoo Iwakuma
- 5959 5959 利用特异性小分子抑制剂对三阴性乳腺癌中的HuR进行治疗性靶向 Therapeutic targeting of HuR using a specific small-molecule inhibitor in triple negative breast cancer Arundhathi Dev J R, Ajay Gogia, Sandeep R. Mathur, Ashutosh Mishra, Chandra Prakash Prasad
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5960 · PDF 同种异体调节性T细胞的CRISPR-Cas工程改造揭示类固醇受体共激活因子3(SRC-3)在维持FOXP3表达和抑制功能中的必要作用 CRISPR-Cas engineering of allogeneic regulatory T cells reveals an essential role for steroid receptor coactivator 3 (SRC-3) in maintaining FOXP3 expression and suppressive function Subhashree Pradhan, Bryan Nikolai, Aiden Lynn Moser, Davis Alexander Graham, Lanz Rainer, Bert W O'Malley, David Lonard
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5961 · PDF METTL3在结直肠癌中的作用 The roles of METTL3 in colorectal cancer Hung Mai, Sidi Zhao, DEBANJAN SAHA, Jace Webster, Li Lin, Emily Rozycki, Ashna Agarwal, Muheng Liao, Christopher Maher
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5962 · PDF METTL1介导的缬氨酸tRNA m7G修饰驱动胰腺导管腺癌进展 METTL1-mediated m7G modification of valine tRNAs drives pancreatic ductal adenocarcinoma progression jiabei zhu, Qi Zhang, Rui Su, Qiuhui Pan, Ajay Goel
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5963 · PDF mTORC1-eIF4A1依赖性的致癌脂肪酸去饱和酶翻译调控 mTORC1-eIF4A1 dependent translational regulation of oncogenic fatty acid desaturases Yujin Chun, Joohwan Kim, Izabelle Le, Cuauhtemoc B. Ramirez, Won-Suk Song, Cholsoon Jang, Gina Lee
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5964 · PDF 单细胞多组学分析揭示小细胞肺癌的调控机制 Single-cell multi-omics profiling unveils the regulatory mechanisms of small cell lung cancer Charny Park, Namhee Yu, Jung-Hyun Kim, Sehwa Hong, Mihwa Hwang, Bo Ram Song, Sunshin Kim, Soo Young Cho, Beung-Chul Ahn, Ji-Youn Han
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5965 · PDF Plk1-BRN2信号轴驱动去势抵抗性前列腺癌中的谱系可塑性 Plk1-BRN2 signaling axis drives lineage plasticity in castration-resistant prostate cancer Fatemeh Seilani, Meng Wu, Jia Peng, Mohammad Esfini Farahani, Xinyi Wang, Jinghui Liu, Yanquan Zhang, Ruixin Wang, Xiaoqi Liu
- 5966 5966 条形码化的细胞状态特异性转录因子筛选鉴定出SIX1是神经母细胞瘤可塑性与耐药性的关键调控因子 Barcoded cell state specific transcription factors screen identifies SIX1 as a critical regulator of neuroblastoma plasticity and drug resistance Xingyu Liu, Ying Wu, Haiyan Lei, Wendy Fang, John Shern, Zhihui Liu, Carol Thiele
- 5967 5967 转录因子基因TGIF1的过表达抑制NRAS驱动的急性髓系白血病细胞的增殖 Overexpression of the transcription factor gene TGIF1 inhibits proliferation in NRAS-driven acute myeloid leukemia cells Michael Roberts, Herryung Choi, Chase Mitchell Weizer, Helena Holley, Mishra Pranav, Ellsa Hritz, Jeffrey Forrester
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5968 · PDF FOXM1作为乳腺癌脑转移中转移性生长的关键调控因子 FOXM1 as a key regulator of metastatic outgrowth in brain metastasis of breast cancer Shannon Cartay Kalsi, Lara Luzietti, Aoibheann Dowd, Aoibhín M. Powell, Gabriela Gomez, Jason McGrath, Nicola S. Cosgrove, Hian Hui Young, Arnold D. K. Hill, Stefan Prekovic, Leonie S. Young, Damir Varešlija
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5969 · PDF 剪接变异性与致癌异构体:变革我们对HNSCC生物学的理解 Splicing variability and oncogenic isoforms: Transforming our understanding of HNSCC biology Daria Gaykalova, Madeleine Ndahayo, Ishita Gupta
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5970 · PDF 挽救VHLD错义突变以预防或治疗肾细胞癌 Rescuing VHLD missense mutations to prevent or treat renal cell carcinoma Shabnam Pirestani
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5971 · PDF MYC与KDM7A协作抑制SIDT2并削弱dsRNA介导的抗肿瘤免疫 MYC cooperatives with KDM7A to repress SIDT2 and dampens dsRNA-mediated anti-tumor immunity Tae-Won Lee, Kyung-min Lee, Carlos L. Arteaga, Ariella B. Hanker, Seung Han Son
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5972 · PDF 来自西班牙裔/拉丁裔患者的儿童B-ALL(伴或不伴高危遗传性结构变异)的转录失调 Transcriptional dysregulation of pediatric B-ALL derived from Hispanic/Latino patients with and without high-risk genetic structural variants Joseph Schramm, Brindangnanam Pownraj, Bing He, Yali Ding, Daniel Bogush, Singh Chingakham, Katarina Dovat, Diwakar Bastihalli Tukaramrao, Sinisa Dovat