Mechanisms of Metastasis

• 6087 · PDF SOX2-LGR5信号在卵巢癌细胞应对锚定丧失时介导其存活 SOX2-LGR5 signaling mediates ovarian cancer cell survival in response to loss of anchorage. Shriya Kamlapurkar, Amal T. Elhaw, Mythreye Karthikeyan, Nadine Hempel
• 6088 · PDF USP15通过调节细胞周期检查点和DNA损伤信号促进卵巢癌进展 USP15 promotes ovarian cancer progression by modulating cell cycle checkpoints and DNA damage signaling Ayokunnumi Sewanu Ogunsanya, Noel Amadu, Achuth Padmanabhan
• 6089 · PDF 在高级别浆液性卵巢癌基因工程小鼠模型中对NR2F2在肿瘤起始和进展过程中功能的全面分析 Comprehensive analysis of NR2F2 functions during tumor initiation and progression in a genetically engineered mouse model of high-grade serous ovarian carcinoma Miranda Mansolf, Danqi Liao, Samantha Goncalves Novo, Tobias M. Hartwich, Jasmine Jathan, Kevin Yang, Viktoriia Kolesnyk, Smita Krishnaswamy, Yang Yang-Hartwich
• 6090 · PDF eIF3h作为三阴性乳腺癌进展驱动因素的特征分析 Characterization of eIF3h as a driver of triple negative breast cancer progression Tiffany J. Rios-Fuller
• 6091 · PDF 神经元构筑者Pax6协调干性和脑转移进展 Neuronal architect Pax6 orchestrates stemness and brain metastatic progression Laiba Anwar, Asad Ur Rehman, Md Arafat Khan, Mohammad Abbas Ali Zaidi, Zahraa Wajih Alsafwani, Nivedeta Krishna Kumar, Mahek Fatima, Aatiya Ahmad, Parvez Khan, Moorthy P. Ponnusamy, Metin Uz, Juan A. Santamaria-Barria, Surinder K. Batra, Mohd Wasim Nasser
• 6092 · PDF STAT5调节STAT3及三阴性乳腺癌的侵袭性行为 STAT5 modulates STAT3 and the aggressive behaviors of triple negative breast cancer Alexandra E. Temple, Emily C. Armlin, Sarah R. Walker
• 6093 · PDF 研究应激诱导的SIPA1核内重定位在乳腺癌转移中的作用 Investigating the role of stress induced nuclear relocalization of SIPA1 in breast cancer metastasis Nirupama S. Kotian, Kent W. Hunter
• 6094 · PDF Caveolin-1调节三阴性乳腺癌的干性和化疗敏感性 Caveolin-1 modulates stemness and chemosensitivity in triple negative breast cancer Shreya Pokharel, Naveen Chintala Ramulu, Biplov Sapkota, Dhirendra Pratap Singh, Abhishek Pandit, Shilpa Thota, Rizwana Begum, Shobhit Srivastava, Yuxio Yo, Shang Su, Dayanidhi Raman, Joseph Francis
• 6095 · PDF 乳腺癌肝转移：一种新的小鼠模型系统 Breast cancer metastasis to the liver; a new mouse model system Jesus Garcia-Lerena, Eran Andrechek
• 6096 · PDF 一种新型多西环素诱导型乳腺EZH2过表达模型的特征分析 Characterization of a novel doxycycline inducible model of EZH2 overexpression in mammary glands Ahmad Eido, Maria E. Gonzalez, LiJyun Syu, Andrzej A. Dlugosz, Celina G. Kleer
• 6097 · PDF 体内CRISPR敲除筛选揭示核糖体生物发生是黑色素瘤转移的驱动因素和潜在治疗靶点 In vivo CRISPR knockout screen reveals ribosome biogenesis as a driver and a potential therapeutic target for melanoma metastasis. Anna Fakhardo, Chethana Gowda, Emily Johnson, Ricardo Petroni, Vivek Tomar, Zhenqiu Liu, Andres Blanco, Jacob Janssen, Irina Elcheva, Matthew Lanza, Serge Fuchs, Vladimir Spiegelman
• 6098 · PDF 特征性表面聚糖结构促进galectin-8介导的血管黏附和人黑色素瘤的转移性播散 Signature surface glycan architecture promotes galectin-8-mediated vascular adhesion and metastatic dissemination of human melanomas Jose Souchak, Basilio Garcia, Norhan B. B. Mohammed, Lee Seng Lau, Ismaray Govea, Brandon Fernandez, Charles J. Dimitroff
• 6099 · PDF 通过化合物筛选鉴定调控结直肠癌干性和转移的关键通路 Identification of key pathways regulating colorectal cancer stemness and metastasis through compound screening Teruaki Fujishita, Yanqing Niu, Masahiro Aoki
• 6100 · PDF MYADM驱动RhoA依赖的阿米巴样可塑性和染色质重塑以促进转移 MYADM drives RhoA-dependent amoeboid plasticity and chromatin remodeling to promote metastasis Tai-Lung Cha, Yi-Ta Tsai, En-Ting Liu
• 6101 · PDF 血影蛋白SPTAN1缺失触发基因组不稳定性和膀胱癌肿瘤生长 Spectrin SPTAN1 loss triggers genome instability and tumor growth in bladder cancer Jim Sheu, Chun-Yu Su
• 6102 · PDF 对染色质调节因子的体内CRISPR筛选揭示食管癌肺转移的p53依赖性驱动因素 In vivo CRISPR screening of chromatin regulators reveals p53-dependent drivers of lung metastasis in esophageal cancer Raul Navaridas, Gizem Efe, Ali Iftikhar, Karen J. Dunbar, Katherine Cunningham, Emily Esquea, Noriyuki Noriyuki, Constanza Tapia Contreras, Alice E. Shin, Francisco J. Sánchez-Rivera, Chao Lu, Anil K. Rustgi
• 6103 · PDF 染色体外环状DNA介导的NOSIP扩增驱动肝细胞癌中OXPHOS依赖的转移 Extrachromosomal circular DNA-mediated NOSIP amplification drives OXPHOS-dependent metastasis in hepatocellular carcinoma Xiaorong Lin, Yusheng Luo, Yuxi Pan, Guofei Deng, Yuqing Lin, Yuzhi Zhang, Jiancheng Wang, Shuo Fang
• 6104 · PDF STK11缺失增强应激适应程序，支持KRAS驱动型肺腺癌循环肿瘤细胞的剪切力耐受性 STK11 loss enhances stress-adaptive programs supporting shear resilience in circulating tumor cells from KRAS-driven lung adenocarcinoma Anna Showalter, Princess Rodriguez, David Joseph Seward, Paula B. Deming, Melissa Nicole Scheiber
• 6105 · PDF 胆囊收缩素B受体在肝细胞癌中的表观遗传调控与靶向治疗 Cholecystokinin-B receptor epigenetic regulation and targeted therapy in hepatocellular carcinoma Martha Gay, Hong Cao, Wenqiang Chen, Jill P. Smith
• 6106 · PDF 靶向细胞内Galectin-3破坏BRAF V600E突变的休眠细胞播散并恢复甲状腺癌的化疗敏感性 Targeting intracellular Galectin-3 disrupts BRAF V600E mutated dormant cell dissemination and restores chemosensitivity in thyroid cancer Chiara Modica, Vincenzo Davide Pantina, Francesco Verona, Roberta Drago, Giulia Bozzari, Matilde Todaro, Giorgio Stassi
• 6107 · PDF NF-κB信号的激活驱动STK11缺陷型肺腺癌的促转移程序 Activation of NF-κB signaling drives pro-metastatic programs in STK11-deficient lung adenocarcinoma Allison R. Racela, Shannon M. Prior, Sean M. Lenahan, Cole M. Royer, David Joseph Seward, Paula B. Deming

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