Metastatic Niches and Microenvironment

• 6143 · PDF 肿瘤外泌体启动的中性粒细胞IRG1/衣康酸轴唤醒休眠肿瘤细胞并促进肺转移 Tumor exosome-initiated neutrophil IRG1/itaconate axis awakens dormant tumor cells and promotes lung metastasis Yue Deng, Jialin Lu, Xiao Yang, Lingyi Kong, Chao Wan, Kunyu Yang
• 6144 · PDF 足底皮肤中的位点特异性微环境程序赋予肢端黑色素瘤更高的转移能力 A site-specific microenvironmental program in plantar skin confers heightened metastatic capacity to acral melanomas Marie Elena Portuallo, Tyler Aprati, Limin An, Steffanus Pranoto Hallis, Kuai Yu, MiKaela N. Field, Sheri L. Holmen, David Liu, Vito Rebecca
• 6145 · PDF sirtuin 1对小细胞外囊泡产生的调控作为乳腺癌转移的决定因素 Regulation of small extracellular vesicle production by sirtuin 1 as a determinant of breast cancer metastasis Yu-Wei Chang, Michael Guo, Aidan M. Quinn, Anthony M. Chen, James J. Mullmann, Andrew D. Miller, Richard A. Cerione, Marc A. Antonyak, Robert S. Weiss
• 6146 6146 钨增强乳腺癌转移潜在驱动因素的分析：骨髓脂肪细胞的纵向研究 Analysis of potential drivers of tungsten-enhanced breast cancer metastasis: A longitudinal study of bone marrow adipocytes Charlotte Marie McVeigh, Jennifer A. Tjung, Jorge L. Moreno, Sydnee J. Yazzie, Lauren K. Heine, Grace A. Picha, Guy W. Herbert, Sebastian Medina, Alicia M. Bolt
• 6148 · PDF GPR35作为阻止乳腺癌进展和溶骨性骨转移的治疗靶点 GPR35 as a therapeutic target to halt breast cancer progression and osteolytic bone metastasis Gunjan Sharma, KM Abdullah, Seema Singh, Ajay Singh, Jawed Siddiqui
• 6149 · PDF 致癌性 ASPP2 kappa 在肿瘤微环境中发挥调控作用并在 TNBC 模型中促进转移 Oncogenic ASPP2 kappa exerts a regulatory role within the tumor microenvironment and promotes metastasis in TNBC models Cornelia Wincek, Alessia Ruiba, Wenfeng Liu, Sakthi Kembu Chettiar Ravichandran, Marcus M. Schittenhelm, Kerstin Maria Kampa-Schittenhelm
• 6150 · PDF 组织蛋白酶 G 作为乳腺癌肿瘤可塑性和溶骨性转移的核心调控因子 Cathepsin G as a central regulator of tumor plasticity and osteolytic metastasis in breast cancer Ridhi Bhola, Reegan Sturgeon, Gabriel Tonucci, Rakesh K. Singh
• 6154 · PDF 单细胞图谱揭示乳腺癌脑转移中由肿瘤微环境主导的生态系统 A single-cell atlas reveals a tumor microenvironment-dominated ecosystem in breast cancer brain metastasis Chuanbao Zhang, Wang Jia, Lei Xing, Md Tauhidul Islam
• 6155 · PDF S-亚硝基化 COX-2 是一种受微环境调控的间充质表型乳腺癌生物标志物 S-Nitrosylated COX-2 is a microenvironment-regulated breast cancer biomarker of mesenchymal phenotypes Reuben J. Hoffmann, AeSoon Bensen, Mark Dane, Jane Arterberry, Rebecca Smith, James Korkola, Pepper Schedin
• 6156 · PDF 与结直肠癌转移前生态位相关的 Omega-6 脂质-基因模块 Omega-6 lipid-gene module linked to colorectal cancer pre-metastatic niche Ramani Soundararajan, Lance Pflieger, Gunjan Upadhyay, Michelle M. Maurin, Mingli Yang, Michael Schell, McKayla Carr, Ahalya Sekhar, Rachel Kenis, Heiman Wang, Michael Nebozhyn, Andrey Loboda, Aejaz Nasir, W. Jack Pledger, Ganesh V. Halade, Timothy J. Yeatman
• 6157 · PDF 驱动结直肠癌肝转移的肿瘤生态位的单细胞表征 Single-cell characterization of tumor niches driving liver metastasis in colorectal cancer Jinho Jang, Yoojeong Seo, Kyung Pil Ko, Jie Zhang, Sohee Jun, Jae-Il Park
• 6158 · PDF 衰老的肿瘤相关巨噬细胞促进胃癌腹膜转移生态位的形成 Senescent tumor-associated macrophages promote peritoneal metastatic niche formation in gastric cancer Tadahito Yasuda, Mayu Yasuda, Atsuko Yonemura, Fabio de Mello, Feng Guo, Boping Jing, Hudie Li, Takatsugu Ishimoto, Yaoqi Alan Wang
• 6159 · PDF 雄激素剥夺治疗下原发性和淋巴结转移性前列腺癌中癌细胞及其微环境的共同演化 Co-evolution of cancer cells and their microenvironment of primary and lymph node metastatic prostate cancer under androgen deprivation therapy Ping Xu, Yuehui Zhao, Yun Yan, Rui Ye, Chenling Tang, Emi Sei, Shanshan Bai, Tuan Tran, Cole Ruoff, Christine Ly, Keyi Zhu, Miao Zhang, Bila A. Siddiqui, Sumit K. Subudhi, Paul Corn, Christopher J. Logothetis, Patricia Troncoso, Amado J. Zurita-Saavedra, Nicholas Navin
• 6160 · PDF TRPV6/CXCR4信号复合物作为预防去势抵抗性前列腺癌成骨性骨转移的治疗靶点 TRPV6/CXCR4 signaling complexes as therapeutic targets to prevent osteoblastic bone metastasis in castration-resistant prostate cancer Clement Cordier, Aurélien Haustrate, Adriana Mihalache, Erika Duval, Emilie Desruelles, Corentin Spriet, Lofti Slimani, Baptiste Casel, Laurent Allart, Pierre Gosset, Natalia Prevarskaya, V'yacheslav Lehen'kyi

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