PO.TB10.11 · 肿瘤生物学
Fibroblasts as Architects of the Tumor Microenvironment
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6024 · PDF 解码乳腺癌中基质驱动炎症的新机制 Decoding new mechanisms of stromal-driven inflammation in breast cancer Fernanda G. Kugeratski, Lisa Neilson, Adrian Kacperczyk-Perdyan, Juan R. Hernandez-Fernaud, Sergio Lilla, Jakub Mieczkowski, Sara Zanivan
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6025 · PDF Transgelin阳性癌症相关成纤维细胞促进胰腺癌进展 Transgelin-positive cancer-associated fibroblasts promote pancreatic cancer progression Keiko Shinjo, Xingxing Wang, Kohei Kumegawa, Reo Maruyama, Shinji Mii, Yukihiro Shiraki, TATSUNORI NISHIMURA, Yoshiteru Murofushi, Miho Suzuki, Atsushi Enomoto, Yutaka Kondo
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6026 · PDF 铁代谢是癌症相关成纤维细胞活化的基础 Iron metabolism underlies the activation of cancer associated fibroblasts Kedi Huang, Minh Duc Pham, Chang-il Hwang
- 6027 6027 癌症相关成纤维细胞来源的PDE3A促进脂筏调控的IGF-1R易位及三阴性乳腺癌的免疫治疗耐药 Cancer associated fibroblasts-derived PDE3A promotes lipid raft-regulated IGF-1R translocation and immunotherapy resistance in triple negative breast cancer Na Hao
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6028 · PDF CAF来源的ANKRD1对肺癌肿瘤微环境的影响 The impact of CAF-derived ANKRD1 on the lung cancer tumor microenvironment Kazuhiro Okada, Ken Suzawa, Shunsuke Mori, Kenta Manabe, Ryunosuke Fujii, Kousei Ishimura, Ryota Fujiwara, Kazuya Hisamatsu, Ryo Yoshichika, Atsushi Matsuoka, Yuma Fukumoto, Hidejiro Torigoe, Kazuhiko Shien, Shinichi Toyooka
- 6029 6029 SFRP4+癌症相关成纤维细胞驱动肝细胞癌中IL-6/STAT3介导的EMT和免疫抑制性肿瘤微环境 SFRP4+ cancer-associated fibroblasts drive IL-6/STAT3-mediated EMT and immunosuppressive tumor microenvironment in hepatocellular carcinoma Hyo Jung Cho, Sujin Kim, Hye Ri Ahn, Minsu Kwon, Myungchan Park, Tae Jun Park
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6030 · PDF Gli2增加骨桥蛋白表达以改变癌症相关成纤维细胞行为 Gli2 increases Osteopontin expression to alter cancer associated fibroblast behavior Zenaida Fuentes, Rachel Mangano, Jade Miller, Erik Beadle, Julie Rhoades
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6031 · PDF Treg-成纤维细胞轴塑造结直肠癌中的免疫抑制性肿瘤微环境 The Treg-fibroblast axis shapes the immunosuppressive tumor microenvironment in colorectal cancer Liqian Ma, Mingying Bi, Bonnie Huang, Lilian Ho, Hin Ching Lo, Min Liao, Gaurav Mehta, Nicole Belmar, Michelle Chen, Tifani Anton, Areej Ammar, Haiyan Li, Kyle Halliwill, Kate MacDonald
- 6032 6032 癌症相关成纤维细胞亚型myCAF、iCAF和apCAF可能与胃癌患者的不良预后特征相关 Subtypes of cancer-associated fibroblasts, myCAF, iCAF, and apCAF, might be associated with adverse prognostic signature of patients with gastric cancer DONGHENG MA, Hinano Nishikubo, Tomoya Sano, Daiki Imanishi, Takashi Sakuma, Canfeng Fan, Yurie Yamamoto, Masakazu Yashiro
- 6033 6033 癌症相关成纤维细胞在胰腺癌和胆道癌中的不同作用——癌症相关成纤维细胞作为胆道癌中的肿瘤抑制因子 Different roles of cancer-associated fibroblasts in pancreatic cancer and biliary tract cancers cancer-associated fibroblasts as a tumor suppressor in biliary tract cancers Ryota Tanaka, Kenjiro Kimura, Naoki Tani, Shimpei Eguchi, Daisuke Inoue, Takuto Yasuda, Changgi Ahn, Koichi Nakanishi, Kosuke Hatta, Shigeaki Kurihara, Jun Tauchi, Sadaaki Nishimura, Masahiko Kinoshita, Kohei Nishio, Hiroji Shinkawa, Takeaki Ishizawa
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6035 · PDF 非免疫基质重编程塑造乳腺癌免疫治疗耐药:来自小鼠模型的启示 Non-immune stromal reprogramming shapes breast cancer immunotherapy resistance: insights from mouse models Yujia Yue, Stephanie Mittman, Rohit Reja, Julia Lau, Minyi Shi, Ana Xavier-Magalhaes, Jonathan Paw, Carolina De Amat Herbozo, Marco De Simone, Yan Qu
- 6036 6036 小鼠胰腺肿瘤中的抗原呈递型癌症相关成纤维细胞通过 CCL22 差异性地调控调节性 T 细胞的表型与功能 Antigen-presenting cancer-associated fibroblasts in murine pancreatic tumors differentially control regulatory T cell phenotype and function via CCL22 Saumya Maru, Meredith Wetzel, Jacob Mitchell, Nicole Gross, Lalitya Andaloori, Kathryn Howe, Emma Kartalia, Guanglan Mo, James Leatherman, Won Jin Ho, Elana Judith Fertig, Luciane Tsukamoto Kagohara, Edward J. Pearce, Elizabeth M. Jaffee
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6037 · PDF 在胃癌中鉴定出一种免疫激活和肿瘤抑制型的癌症相关成纤维细胞亚型 An immune-activating and tumor-suppressive subtype of cancer-associated fibroblasts identified in gastric cancer HUAITAO WANG, Takashi Semba, Atsuko Yonemura, Takatsugu Ishimoto
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6038 · PDF 结直肠癌中癌症相关成纤维细胞亚型异质性影响原发肿瘤侵袭 Cancer associated fibroblast subtype heterogeneity in colorectal cancer influences primary tumor invasion Bethany Haliday, Carly Strelez, Eileen Fung, Shannon M. Mumenthaler
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6039 · PDF 癌细胞驱动的 HIF-1alpha 激活增强肺肿瘤微环境中癌症相关成纤维细胞的运动能力 Cancer cell-driven HIF-1alpha activation enhances the motility of cancer-associated fibroblasts in the lung tumor microenvironment Jihye Park, Sieun Lee, Jonathan M. Kurie, Young-Ho Ahn
- 6040 6040 靶向 EP3⁺FAP⁺ 基质重编程揭示早期复发性肝细胞癌的一个治疗易感性 Targeting EP3⁺FAP⁺ stromal reprogramming uncovers a therapeutic vulnerability in early recurrent hepatocellular carcinoma guiqi zhu, guan zhiqi, yinghong shi, weiren liu, zheng tang, Kang Wang, jia fan
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6041 · PDF 非达霉素靶向 PDGFR⁺ 癌症相关成纤维细胞以抑制结直肠癌进展 Fidaxomicin targets PDGFR⁺ cancer-associated fibroblast to restrain colorectal cancer progression Haoxiang Zhang, Xudong Zhu, Chang Li, Yinping Jiang, Yuning Zhou, B. Mark Evers, Qingding Wang
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6042 · PDF 靶向癌症相关成纤维细胞中的 GABA 信号以减轻胰腺癌中的免疫抑制 Targeting GABA signaling in cancer associated fibroblasts to reduce immunosuppression in pancreatic cancer Ariana Musa de Aquino, Myree Graves, Kyra Langley, Peter Sajjakulnukit, Ian Loveless, Nina Steele, Julie Clark, Alexander Muir, Costas Andreas Lyssiotis, Ralph Francescone, Débora B. Vendramini-Costa, Guilaume Cognet G, David Kwon
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6043 · PDF 利用全反式维甲酸使肝转移性结直肠癌相关成纤维细胞失活 Deactivating liver metastatic colorectal cancer-associated fibroblasts with all-trans retinoic acid Brandon Choi, Ken Huang, Yuyuan Zhou, Seungil Kim, Eileen Fung, Shannon M. Mumenthaler
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6044 · PDF DKK1与癌症相关成纤维细胞在子宫内膜癌各分子亚型中的免疫抑制作用 Immunosuppressive role of DKK1 and cancer-associated fibroblasts across molecular subtypes of endometrial cancer Alessandro Canella, Danielle Glassman, Keith Brownewell, Caprice Eisele, Aharon Gideon Freud, Casey Cosgrove
- 6045 6045 探索促进CLL细胞在与基质成纤维细胞接触时存活的表面相互作用因子 Exploring surface interactors promoting viability of CLL cells in contact with stromal fibroblasts Uday Aditya Sarkar, Domenico Maisano, Stacey M. Fernandes, Kiyomi Mashima, Colin Mcnulty, Nikhil C. Munshi, Jennifer R. Brown, Fabiana Perna, Eugenio Morelli, Paolo P. Ghia
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6046 · PDF 肝外胆管癌中癌症相关成纤维细胞微龛的空间转录组学分析 Spatial transcriptomic profiling of cancer-associated fibroblast niches in extrahepatic cholangiocarcinoma Giulia Petroni, Simone Romagnoli, Daniele Lavacchi, Giulia Massaro, Francesca Rizzo, Elena Alexandrova, Costanza Winchler, Alfonso Carleo, Gian Luca Grazi, Daniele Rossini, Luca Messerini, Matteo Benelli, Serena Pillozzi, Lorenzo Antonuzzo
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6047 · PDF 肌成纤维细胞与肿瘤之间的CTHRC1-TGFb串扰驱动早期肺腺癌侵袭 CTHRC1-TGFb crosstalk between myofibroblasts and tumors drives invasion in early-stage lung adenocarcinoma Abhilasha Sinha, SEUNGYEUL YOO, Nanzeeba Faraby, Thinh Nguyen, Hideo Watanabe, Alexander Tsankov, Jun Zhu, Charles A. Powell
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6048 · PDF CAF分泌的骨膜蛋白通过上调MMP1促进BRAF突变型甲状腺乳头状癌的肿瘤侵袭性 CAF-secreted periostin promotes tumor aggressiveness in BRAF - mutant papillary thyroid carcinoma by upregulating MMP1 ZHUORAN LIU, JINYUE LIU, JIE KUANG, WEIHUA QIU
- 6049 6049 软骨寡聚基质蛋白、癌症相关成纤维细胞表型及多功能蛋白聚糖蛋白水解调控结直肠癌中CD8+ T细胞浸润 Cartilage oligomeric matrix protein, cancer-associated fibroblast phenotypes, and versican proteolysis modulate CD8+ T cell infiltration in colorectal cancer Cadence E. Brown, Ruchi Shah, Cindy Wuerz, Isoline M. Donohue, Katherine A. Johnson, Cheri Pasch, Dustin A. Deming
- 6051 6051 胰腺肿瘤表达的生长因子在人成纤维细胞中激活一种与不良预后相关的神经样程序 Pancreatic tumor expressed growth factors activate a neural-like program in human fibroblasts which is associated with poor prognosis Myriam Iliana Ibanez Rios, Maëlle Batardiere, Alexandre Archambault-Marsan, Elham Dianati Ajibisheh, Vincent Quoc-Huy Trinh, David J.H F. Knapp