PO.ET06.06 · 实验与分子治疗
Tumor Diagnostics, Prognostics, and Therapeutic Outcomes
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7209 · PDF 3p染色体突变驱动原发性ccRCC中独特且非冗余的转录程序 Chromosome 3p mutations drive unique and non-redundant transcriptional programs in primary ccRCC Parker D. Mathews, Eric Knoche, Martin W. Schoen, Russell Pachynski
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7210 · PDF 胃腺癌中频繁的区域内PLAP表达异质性 Frequent intra-regional PLAP expression heterogeneity in gastric adenocarcinomas Morton Freytag, Eike C. Burandt, Florian Viehweger, Viktor Reiswich, Christina Tsourlakis, Ronald Simon, Claudia Hube-Magg, Martina Kluth, Waldemar Wilczak, Fiete Gehrisch, Thorben W. Fruendt, Thomas Roesch, Philip Dautel, Guido Sauter, Till S. Clauditz, Nina Schraps, Stefan Steurer, Clara Luehr
- 7211 7211 高瘤内同质性和肿瘤特异性使uroplakin 3b(Upk3b)成为恶性间皮瘤中一个有前景的治疗靶点 High intratumoral homogeneity and tumor specificity makes uroplakin 3b (Upk3b) a promising therapeutic targetin malignant mesothelioma Sönke von Weihe, Frank Elsholz, Philipp Busch, Fiete Gehrisch, Nina Schraps, Martina Kluth, Maria C. Tsourlakis, Katharina Möller, Maximilian Lennartz, Veit Bertram, Florian Viehweger, Florian Lutz, Birgit Hantzsch-Kuhn, Till Olchers, David B. Ellebrecht, Christoph Fraune, Ronald Simon, Guido Sauter, Martin Reck, Stefan Steurer
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7212 · PDF MRE11缺失见于来自多种不同肿瘤类型的一小部分癌症 MRE11 deficiency occurs in a small group of cancers from various different tumor entities Viktor Reiswich, Henry Recksiek, Katharina Möller, Florian Lutz, Florian Viehweger, Nina Schraps, Fiete Gehrisch, Christina Tsourlakis, Georgia Makrypidi-Fraune, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Guido Sauter, Andreas H Marx, Ronald Simon, Till Krech, Stefan Steurer, Christoph Fraune, Sarah Minner, Viktoria Chirico, Bertram Veith, Clara Luehr, Cosima Völkel, Morton Freytag, Natalia Gorbokon, Maximilian Lennartz, Eike C. Burandt, Anne Menz, Clara von Bargen
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7213 · PDF 叶酸受体α抗体-药物偶联物mirvetuximab soravtansine-gynx在卵巢癌PDX模型中的评估 Evaluation of folate receptor-alpha antibody-drug conjugate mirvetuximab soravtansine-gynx in ovarian cancer PDXs Daniel Ciznadija, Hsiu-Wen Tsai, Marianna Zipeto, Markus Hippich, Gilad Silberberg, Stefano Cairo, Michael Ritchie
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7214 · PDF 基于LymphGen的DLBCL PDX模型分层反映了临床肿瘤的复杂性 LymphGen-based stratification of DLBCL PDX models mirrors clinical tumor complexity Marianna Zipeto, Mike Ritchie, Markus Hippich, Daniel Ciznadija, Gervaise Henry, Stefano Cairo, Gilad Silberberg
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7215 · PDF OTP、CD44、Ki67生物标志物组合可预测术前肺NET活检标本的预后 The OTP, CD44, Ki67 biomarker panel predicts prognosis in preoperative lung NET biopsy specimens Tijmen JJ van Weert, Laura Moonen, Lisa M. Hillen, Jan von der Thüsen, Michael A. den Bakker, Lisa MV Lap, PALGA Group, Ronald A. Damhuis, Wieneke A. Buikhuisen, Anne-Marie C. Dingemans, Jules L. Derks, Ernst Jan M. Speel
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7216 · PDF HMGB1表达与结直肠癌的不良肿瘤特征和预后不良相关 HMGB1 expression is linked to unfavorable tumor features and poor prognosis in colorectal cancers Nina Schraps, Katharina Möller, Viktor Reiswich, Florian Viehweger, Maria Christina Tsourlakis, Georgia Makrypidi-Fraune, Claudia Hube-Magg, Martina Kluth, Till Krech, Christoph Fraune, Andreas H Marx, Fiete Gehrisch, Baris Mercanoglu, Nathaniel Melling, Thilo Hackert, Ronald Simon, Guido Sauter, Morton Freytag
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7217 · PDF 间皮素表达的均一性与其在非小细胞肺癌中的表达水平密切相关 Homogeneity of mesothelin expression is tightly linked to its levels of expression in non-small cell lung cancer Philipp Busch, Fiete Gehrisch, Nina Schraps, Katharina Möller, Seyma Büyücek, Maximilian Lennartz, Florian Viehweger, Christoph Fraune, Christian Bernreuther, Ronald Simon, Guido Sauter, Till Olchers, Florian Lutz, Martina Kluth, Georgia Makrypidi-Fraune, Stefan Steurer, Martin Reck, Sönke von Weihe
- 7218 7218 EBV LMP1与MYD88 L265P突变对PD-1抑制剂在ABC-DLBCL中疗效的协同机制的初步探索 Preliminary exploration of the synergistic mechanism between EBV LMP1 and MYD88 L265P mutation on the efficacy of PD-1 Inhibitors in ABC-DLBCL Chang Wang, Yingtao Lin, Jiesong Wang
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7219 · PDF Nectin-4在多种不同癌症类型中丰富表达 Nectin-4 expression is abundant in many different cancer entities Clara Luehr, Pia Lemcke, Katharina Möller, Florian Lutz, Florian Viehweger, Georgia Makrypidi-Fraune, Martina Kluth, Claudia Hube-Magg, Nina Schraps, Fiete Gehrisch, Christian Bernreuther, Guido Sauter, Andreas H Marx, Ronald Simon, Stefan Steurer, Christoph Fraune, Viktoria Chirico, Till S. Cauditz, Bertram Veit, Clara Von Bargen, Cosima Völkel, Morton Freytag, Nathalia Gorbokon, Maximilian Lennartz, Eike C. Burandt, Anne Menz, Till Krech, Maria C. Tsourlakis, Sarah Minner
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7220 · PDF Claudin-6 (CLDN6) 在多种不同的癌症类型中广泛表达 Claudin-6 (CLDN6) expression is abundant in many different cancer entities Veit Bertram, Anin Sharifi, Katharina Möller, Florian Lutz, Florian Viehweger, Christina Tsourlakis, Georgia Makrypidi-Fraune, Martina Kluth, Christian Bernreuther, Guido Sauter, Andreas H. Marx, Ronald Simon, Fiete Gehrisch, Nina Schraps, Stefan Steurer, Christoph Fraune, Viktoria Chirico, Clara von Bargen, Cosima Völkel, Morton Freytag, Natalia Gorbokon, Maximilian Lennartz, Eike C. Burandt, Anne Menz, Till Krech, Sarah Minner
- 7223 7223 在种族多样化的 HR 阳性乳腺癌队列中评估治疗相关的雌激素信号传导与分子亚型异质性 Evaluating treatment-related estrogen signaling and molecular subtype heterogeneity in a racially diverse HR-positive breast cancer cohort Abigail M. Fielder, Gregory Dyson, Julie Ruterbusch, David Carr, Julie Boerner, Ann G. Schwartz, Kristen S. Purrington
- 7224 7224 beta-Catenin 蛋白的核/胞质易位是 ERG 阴性前列腺癌患者预后不良的强预测因子,但在 ERG 阳性前列腺癌中则不然 Nuclear/cytoplasmic translocation of beta-Catenin protein is a strong predictor of unfavorable patient prognosis in ERG negative but not in ERG positive prostate cancer Florian Lutz, Osman Gökalp, Ronald Simon, Hans Heinzer, Alexander Haese, Sarah Minner, Guido Sauter, Thorsten Schlomm, Martina Kluth, Claudia Hube-Magg
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7225 · PDF TROP2 在原发性和复发性前列腺癌中广泛表达 TROP2 expression is abundant in primary and recurrent prostate cancer Joanthan Jeutner, Ronald Simon, Maximilian Lennartz, Sarah Minner, Eike Burandt, Fiete Gehrisch, Nina Schraps, Martina Kluth, Guido Sauter, Natalia Gorbokon, Florian Viehweger, Hans Heinzer, Alexander Haese, Thorsten Schlomm, Markus Graefen, Stefan Steurer, Ria Schlichter, Christian Bernreuther, David Dum, Andreas Lübcke, Neele Heckmann
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7226 · PDF 肿瘤细胞 ICAM-1 表达在许多肿瘤类型中常见,并在肾细胞癌中与不良肿瘤表型相关 Tumor cell ICAM-1 expression is frequent in many tumor entities and linked to unfavorable tumor phenotype in renal cell carcinomas Clara von Bargen, Finn Wickel, Katharina Möller, Florian Lutz, Florian Viehweger, Georgia Makrypidi-Fraune, Martina Kluth, Claudia Hube-Magg, Christina Tsourlakis, Christian Bernreuther, Guido Sauter, Andreas H Marx, Ronald Simon, Stefan Steurer, Christoph Frauen, Nina Schraps, Fiete Gehrisch, Viktoria Chirico, Bertram Veith, Clara Luehr, Cosima Völkel, Morton Freytag, Natalia Gorbokon, Maximilian Lennartz, Eike C. Burandt, Anne Menz, Till Krech
- 7227 7227 由 Zelenectide Pevedotin 靶向的 NECTIN4 扩增型乳腺癌:扩增与表达频繁、一致且稳定 NECTIN4-a mplified breast cancer targeted by Zelenectide Pevedotin: Amplification and expression are frequent, concordant, and stable Alexander Azizi, Niklas Klümper, Emma Colliver, Alexander Quaas, Birgid Schoemig-Markiefka, Arndt Hartmann, Christoph Kuppe, Manuel Ritter, Viktor Grünwald, Michael Hölzel, Chris Bailey, Gustavo Arruda Bezerra, Nicholas Guthertz, Sergey Nikolaev, Fabrice Andre, Charles Swanton, Johannes Braegelmann, Markus Eckstein
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7228 · PDF 一种新型数字 PCR 检测方法可在遗传性结直肠癌患者中检出 MLH1 变异 A novel digital PCR assay can detect MLH1 variants in patients with hereditary colorectal cancer Matthew Moldenhauer, Aditya Mahadevan, Cameron Hom, Valeria Rangel, Sophie Hasson, Farshid Dayyani, Ning-Hsiang Hsu, Deepika Nathan, Vishal Chandan, Selma Masri, Feng Qiao, Nicholas Pannunzio, Jennifer Brooke Valerin
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7229 · PDF TM-PAP,随处可用:跨物种、多宿主面板实现快速读出 TM-PAP, everywhere you need it: Cross-species, multi-host panel for fast readouts Yue Huang, Xiaomeng Gou, Yao Peng, Jinying Ning, Feng Hao
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7230 · PDF 紫杉醇诱导的化疗性脱发大鼠模型 A paclitaxel-induced rat model of chemotherapy-induced alopecia Simonetta I. Gaumond, Joaquin Jimenez