PO.IM02.05 · 免疫学

Tumor-induced Immune Suppression

28 张海报 25 张含资料时间 Apr 22 2026 9:00AM 区域 Section 9

6989 · PDF RBM10缺失通过非经典STING/NF-κB轴促进KRAS突变型非小细胞肺癌的免疫耐受和PD-1抑制剂耐药 RBM10 loss promotes KRAS -mutant non-small cell lung cancer immune tolerance and PD-1 inhibitor resistance via a non-canonical STING/ NF-κB axis Minh Truong Do, Teng Zhou, Mhd Yousuf Yassouf, Richard Lee, Obada E. Ababneh, Yanhua Tian, Leticia B. Rodriguez, Jayanthi Gudikote, Haniel A. Araujo, Stephanie T. Schmidt, Jing Wang, Frank R. Rojas Alvarez, Luisa M. Solis Soto, Marcelo V. Negrao, Alexandre Reuben, Don L. Gibbons, Jianjun Zhang, John V. Heymach, Ferdinandos Skoulidis
6990 6990 一种分泌型免疫调节配体的鉴定 Identification of a secretory immune regulatory ligand Benjamin Nicholson, Sydney Fisher, Matthew Wren, Weijie Guo, Yuxuan Phoenix Miao
6991 · PDF 活化血小板通过CD62p-PSGL1结合直接黏附从而抑制CTL的抗肿瘤活性 Direct adhesion of activated platelets suppresses anti-tumor activity of CTL through CD62p-PSGL1 binding Sae Nishiguchi, Masaru Yokomura, Yuki Gomibuchi, Seiji Nagano, Takuo Yasunaga, Hiroshi Kawamoto, Satoshi Takagi, Ryohei Katayama
6992 6992 肿瘤干细胞重编程中性粒细胞以建立保护性生态位 Tumor stem cells reprogram neutrophils to establish a protective niche Weijie Guo, Jingyun Luan, Yuxuan Phoenix Miao
6993 · PDF 靶向PDE4A消除一个免疫检查点并释放STING驱动的抗肿瘤免疫 Targeting PDE4A ablates an immune checkpoint and unleashes STING-Driven anti-tumor immunity Yuting Bai, Kejia Xu, Huimin Liu, Haojie Chen, Yi Shi, Rong Xiang
6994 · PDF 脯氨酸代谢竞争驱动BRAF突变型甲状腺癌中CD8⁺ T细胞的铁死亡 Proline metabolic competition drives CD8⁺ T cell ferroptosis in BRAF-mutated thyroid cancer Yuanxing Dong, Xinyue Liu, Xiangqian Zheng
6995 · PDF 转移性结直肠癌的空间免疫图谱 Spatial immune landscape in metastatic colorectal cancer Susrutha Puthanmadhom Narayanan, Chien-Wei Peng, Adrienne Visani, Xiangwei Fang, Andre Luiz N. Targino da Costa, Jingxian Liu, Reyka G. Jayasinghe, Ambrose Plante, John M. Herndon, Jacqueline Mudd, Preet Lal, Wagma Caravan, Kapur B. Dhami, Jennifer Ponce, Robert S. Fulton, Michael Heinz, Milan G. Chheda, Feng Chen, Michael Iglesia, Ryan C. Fields, Li Ding
6996 · PDF MIF信号在胰腺癌中的免疫调节功能与治疗机遇 Immune regulatory functions and therapeutic opportunities of MIF signaling in pancreatic cancer Blake Schwettmann, Fei Peng, Angad Kumar, Valli Annamali, Jason Toombs, Rolf Brekken, Ravikanth Maddipati
6997 · PDF 界定限制多发性骨髓瘤肿瘤微环境中NK细胞功能的机制 Defining mechanisms limiting NK cell function in the multiple myeloma tumor microenvironment Sadia Afrin, Michelle Becker-Hapak, Lyra Morina, Wilbur Song, Jennifer A. Foltz, Alice Zhou, Kunal Shetty, Yeeun Paik, Samuel Ameh, Emily Philips, Timothy Schappe, Mark Foster, Lynne Marsala, Sushanth Pureti, Yoo-Jin Ahn, David Russler Germain, Todd A. Fehniger
6998 · PDF 非甾体抗炎药、对乙酰氨基酚的使用与乳腺肿瘤的体细胞免疫特征 Use of non-steroidal anti-inflammatory drugs, acetaminophen and somatic immune profiles in breast tumors Clara Bodelon, James Hodge, Daniel G. Stover, Melissa A. Troester, Lauren E. McCullough, Alpa V. Patel, Lauren R. Teras
6999 · PDF GDF-15抑制克服对铂类和紫杉类细胞毒性化学免疫治疗的耐药 GDF-15 inhibition overcomes treatment resistance to platinum- and taxane-based cytotoxic chemoimmunotherapy Neha Vashist, Amelie Köhler, Daniel Schätzlein, Sabrina Genßler, Katja Rungger, Hubert Hackl, Matthias Kist, Sarah Lutzenberger, Julia Weigandt, José Medina-Echerverz, Christine Schuberth-Wagner, Thorsten Ross
7000 · PDF 全基因组CRISPR筛选揭示卵巢癌中肿瘤内在的免疫逃逸机制 Genome-wide CRISPR screening reveals tumor-intrinsic immune evasion mechanism in ovarian cancer Junyong Park, Jiho Lee, Hyun Ju Kang, Jin-Ku Lee
7001 · PDF 胶质母细胞瘤中RRP1（ribosomal RNA processing 1，核糖体RNA加工蛋白1）对吞噬作用的肿瘤内在性抑制 Tumor-intrinsic suppression of phagocytosis by RRP1 (ribosomal RNA processing 1) in glioblastoma Eshika Kudaravalli, Amr Elkholy, Mostafa Mohamed, Hasan Alrefai, Saeed Zakakhosravi, Satoru Osuka, Christopher D. Willey, Erin Ahn
7002 · PDF KRAS突变型结直肠癌肿瘤微环境的免疫逃逸特征 Immune evasive characteristics of the KRAS mutant colorectal cancer tumor microenvironment Elizabeth A. Boeree, Katherine A. Johnson, Cheri A. Pasch, Dustin A. Deming
7003 · PDF RKIP-HER2轴调控乳腺癌免疫逃逸 The RKIP-HER2 axis regulates breast cancer immune evasion Ania Khachikian, Mai Ho, Benjamin Bonavida
7005 · PDF 肿瘤细胞CEBPB表达促成微卫星稳定型结直肠癌的T细胞介导免疫逃逸 Tumor cell CEBPB expression contributes to T cell-mediated immune evasion of microsatellite stable colorectal cancer Hye Jeong Yun, Chan Ho Park, Dahye Yun, Hye-Ri Shin, Naeun Park, Changhee Park, Jeong Dong Lee, Kiyeon Kim, Heejun Shim, Hyejin Sim, Se Min Kim, Min Jung Kim, Ji Won Park, Seung-Bum Ryoo, Yoojoo Lim, Seung-Yong Jeong, Kyu Joo Park, Tae-You Kim, Junil Kim, Jae-Kyung Won, Sae-Won Han
7006 · PDF 抑制宫颈癌细胞内的cPLA2alpha可增强抗肿瘤免疫并促进抗PD1检查点免疫治疗的疗效 Inhibiting intracellular cPLA2alpha in cervical cancer cells enhances antitumor immunity and facilitates the efficacy of anti-PD1 checkpoint immunotherapy Yuchao He, Xiangdong Tian, Liwei Chen, Yi Luo, Yu Wang, Lu Chen, Hua Guo
7007 · PDF 缺氧介导的IFI44L抑制及其记忆及其与STING在乳腺癌转移和免疫逃逸中的相互作用 Hypoxia-mediated suppression and memory of IFI44L and its interaction with STING in breast cancer metastasis and immune evasion Rebecca Marker, Aidan Moriarty, Remi Klotz, Min Yu
7008 7008 多组学分析提名SPP1-IL10轴为胃腹膜癌病的新型免疫治疗靶点 Multi-omic analysis nominates SPP1-IL10 axis as a novel immunotherapeutic target in gastric peritoneal carcinomatosis Turcios Lilia, Neelima Hosamani, Ellen Beswick, Joseph Kim, Mautin Barry-Hundeyin
7009 · PDF 从相关到因果：SOX11 驱动一个协调的免疫抑制网络，抑制三阴性乳腺癌中的抗原提呈 From correlation to causation: SOX11 drives a coordinated immune-suppressive network that represses antigen presentation in triple-negative breast cancer Salomat Abdulkhuseynova, Ashok Pullikuth, Lance D. Miller
7010 · PDF 胞啃作用主导的 CLDN18.2 修饰型 CD8+ T 细胞通过葡萄糖代谢重编程诱导的细胞毒性削弱及系统性免疫衰老级联驱动胰腺癌进展 Trogocytosis-orchestrated CLDN18.2-dressed CD8 + T cells drive pancreatic cancer progression via glucose metabolic reprogramming-induced cytotoxicity debilitation and systematic immune senescence-cascade Jingrui Yan, Tianxing Zhou, Jun Yu, Jihui Hao
7011 · PDF ROCK2 调控的 LIF-STAT3 驱动胰腺癌免疫抑制 ROCK2-regulated LIF-STAT3 drives immunosuppression in pancreatic cancer Varunkumar Krishnamoorthy, Sudhakar Jinka, Siddharth Mehra, Phuong Hong Ngoc Tao, Daysi Daniela Manrique, Rimpi Khurana, Yuguang Ban, Vineet Kumar Gupta, Austin Dosch, Nagaraj Nagathihalli
7012 · PDF 单细胞多组学鉴定 B-ALL 中与 MRD 相关的 Tr1 样 CD4 细胞 Single-cell multi-omics identifies MRD-associated Tr1-like CD4 cells in B-ALL Qianyun Luo, Rebecca LaRue, Enoc Granados Centeno, Kyra Bergerud, Michael Farrar, Sean Tracy
7014 · PDF SPIN1 通过诱导 M2 巨噬细胞极化并抑制 CD8+ T 细胞免疫驱动胃癌 PD-1 免疫治疗耐药 SPIN1 drives PD-1 immunotherapy resistance in gastric cancer by inducing M2 macrophage polarization and suppressing CD8⁺ T-cell immunity Beibei Lyu, Zijun Yidan Xu-Monette, Xiaoyan lin
7015 · PDF USP5 抑制 MRE11 内切酶功能以促进肿瘤免疫逃逸 USP5 suppresses MRE11 endonuclease function to facilitate tumor immune escape Chuan-Chun Lee, Wan-Rong Wu, Liang-Chih Liu, Ting-Yi Liao, You-Zhe Lin, Fang-Ying Lin, Yi-Chun Shen, Yuan-Liang Wang, Chih-Hao Lu, Wei-Chung Cheng, Wei-Chao Chang, Yi-Chuan Li, Chih-Tung Lin, Chung-Yu Chen, Sheng-Wen Chen, Hsin-An Shih, Steven Lin, Chen-Yuan Lin, Chang-Fang Chiu, Shao-Chun Wang
7016 · PDF 靶向唾液酸化促进小细胞肺癌的抗肿瘤免疫 Targeting sialylation promotes anti-tumor immunity in small cell lung cancer Alex D. Doan, Kelly Heard, Jackson Fatherree, Mallika Yalangi, Pritha Chanana, Mitchell Kluesner, Daniel S. Hippe, Cody Jenkins, Hannah Kerbyson, Shivani Srivastava, David MacPherson
7017 · PDF EMP2 是调节胶质母细胞瘤中巨噬细胞诱导吞噬作用的潜在免疫治疗靶点 EMP2 is a potential immunotherapeutic target to modulate macrophage-induced phagocytosis in glioblastoma Amr Elkholy, Eshika Kudaravalli, Mostafa Mohamed, Hasan Alrefai, Saeed Zakakhosravi, Satoru Osuka, Christopher D. Willey, Ahn Erin
7018 · PDF CBS-CXCL10信号轴通过在肿瘤微环境中驱动免疫抑制来支持肿瘤进展 The CBS-CXCL10 signaling axis supports tumor progression by driving immune suppression within the tumor microenvironment Fanghui Chen, Fan Yang, Jianqiang Yang, Nabil Saba, Yong Teng

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