PO.TB10.04 · 肿瘤生物学
Microenvironmental Determinants of Therapy Response and Resistance 2
- 7417 7417 Immune system state shapes clinical response to CAR-T therapy in mantle cell lymphoma Vivian Jiang, Qingsong Cai, Hong Kim, Lei Nie, Chengtai Yu, Yang Liu, Yijing Li, Jovanny Vargas, Michael Wang
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- 7419 7419 Comprehensive profiling of primary and metastatic prostate tumors reveals distinct tumor and fibroblast cell states associated with androgen resistance Aleksandar Obradovic, Kwangmin Yoo, Chang Liu, Patrick McCann, Casey R. Ager, Matthew C. Dallos, Samir Zaidi
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- 7422 7422 Investigation of acquired resistance to atezolizumab-bevacizumab in hepatocellular carcinoma: Paired tumor microenvironment analysis in a mouse model and human subjects Tsung-Hao Liu, Li-Chun Lu, Yu-Yun Shao, Shu-Han Yang, Chi-Yuan Yao, Chia-Lang Hsu, Ying-Chun Shen, Ann-Lii A. Cheng, Chih-Hung Hsu
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- 7425 7425 Histologic and tumor microenvironmental features as prognostic markers in mantle cell lymphoma: A digital pathology-based study Hyungjin Kim, Sei Na, Jeong-Ok Lee, Ji Yun Lee, Sang-A Kim, Jin Ho Paik
- 7427 7427 Genomic analysis of microenvironment composition by breast cancer molecular subtype using an integrated single-cell RNA sequencing cohort Constandina (Dina) E. O'Connell, Alexander V. Lobanov, Kevin R. Mott, Daniel P. Hollern, Brian C. Miller, Charles M. Perou
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- 7429 7429 Characterizing the spatial tumor microenvironments of therapy-induced and hereditary mismatch-repair-deficient hypermutated gliomas Chae Yun (Kate) Cho, Bo Zhao, Lingqun Ye, Inés Martín-Barrio, Yonathan Lissanu, Kadir C. Akdemir
- 7430 7430 Transcriptional programs of precursor-exhausted CD8⁺ T cells associated with checkpoint blockade response in NSCLC Ethan Daniel Littlestone, Md Roungu Ahmmad, Xiaoli Zhang
- 7431 7431 Metabolic correlates of measurable residual disease following high dose melphalan conditioning for autologous stem cell transplant in multiple myeloma Qualia Hooker, Timothy Triche
- 7432 7432 Spatial protein profiling of irradiated ER positive breast cancer lymph nodes suggests nodal irradiation modulates immune function Stephanie O. Dudzinski, Elizve N. Barrientos-Toro, Benjamin D. Smith, Simona F. Shaitelman, Sharia Hernandez, Alejandra Serrano, Khan Khaja, Larisa Kostousov, Wei Lu, Rensi Zacharia, Nathan Comeaux, Solis M. Luisa, Aysegul A. Sahin, Maria Gabriela Raso, Jing Wang, Karen Hoffman, Wendy A. Woodward
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- 7437 7437 Decoding tumor microenvironment heterogeneity through spatial microdomains and network biology to predict immunotherapy outcomes A. Burak Tosun, Raymond Yan, Brian Falkenstein, Filippo Pullara, S. Chakra Chennubhotla
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- 7440 7440 Characterization of the metastatic TIME via spatial transcriptomics reveals unique cellular phenotypes post anti-CSF-1R and immuno-chemotherapy Diego Armando Pedroza, Sung Wook Kang, Xiang H.-F. Zhang, Bora Lim, Hyun-Sung Lee, Jeffrey M. Rosen
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- 7442 7442 Cancer chemotherapy-induced accelerated aging is mitigated by activation of the altruistic stem cell defense response Lekhika Pathak, Partha Jyoti Saikia, Upasha Sarmah, Rupam Das, Chayanika Das, Tulika Sarma, Bikul Das
- 7443 7443 Low hypoxia microenvironment and impaired T cell maturation drive immunotherapy resistance in premenopausal triple negative breast cancer Vidya Prasad Nimbalkar, Snijesh V P, Anupama CE, Mahalakshmi S, Annie Alexander, Rakesh Ramesh, Srinath BS, Jyothi S. Prabhu
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- 7445 7445 Effector regulatory T-cell infiltration, ARID1A status, and Ex Vivo anti-PD-1 response in ovarian clear cell carcinoma: Insights from a comparative high-grade serous ovarian cancer cohort Junsik Park, Eun Kyung Kim, Jung Chul Kim, Nari Kim, JooHyang Lee, Sunghoon Kim, Sang Wun Kim, Yong Jae Lee, Jung-Yun Lee
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