PO.TB10.04 · 肿瘤生物学
Microenvironmental Determinants of Therapy Response and Resistance 2
- 7417 7417 免疫系统状态塑造套细胞淋巴瘤对CAR-T治疗的临床反应 Immune system state shapes clinical response to CAR-T therapy in mantle cell lymphoma Vivian Jiang, Qingsong Cai, Hong Kim, Lei Nie, Chengtai Yu, Yang Liu, Yijing Li, Jovanny Vargas, Michael Wang
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- 7419 7419 原发性和转移性前列腺肿瘤的全面图谱分析揭示与雄激素耐药相关的独特肿瘤和成纤维细胞状态 Comprehensive profiling of primary and metastatic prostate tumors reveals distinct tumor and fibroblast cell states associated with androgen resistance Aleksandar Obradovic, Kwangmin Yoo, Chang Liu, Patrick McCann, Casey R. Ager, Matthew C. Dallos, Samir Zaidi
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- 7422 7422 肝细胞癌对阿替利珠单抗-贝伐珠单抗获得性耐药的研究：小鼠模型和人类受试者中配对肿瘤微环境分析 Investigation of acquired resistance to atezolizumab-bevacizumab in hepatocellular carcinoma: Paired tumor microenvironment analysis in a mouse model and human subjects Tsung-Hao Liu, Li-Chun Lu, Yu-Yun Shao, Shu-Han Yang, Chi-Yuan Yao, Chia-Lang Hsu, Ying-Chun Shen, Ann-Lii A. Cheng, Chih-Hung Hsu
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- 7425 7425 组织学与肿瘤微环境特征作为套细胞淋巴瘤的预后标志物：一项基于数字病理学的研究 Histologic and tumor microenvironmental features as prognostic markers in mantle cell lymphoma: A digital pathology-based study Hyungjin Kim, Sei Na, Jeong-Ok Lee, Ji Yun Lee, Sang-A Kim, Jin Ho Paik
- 7427 7427 利用整合的单细胞RNA测序队列按乳腺癌分子亚型分析微环境组成的基因组学研究 Genomic analysis of microenvironment composition by breast cancer molecular subtype using an integrated single-cell RNA sequencing cohort Constandina (Dina) E. O'Connell, Alexander V. Lobanov, Kevin R. Mott, Daniel P. Hollern, Brian C. Miller, Charles M. Perou
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- 7429 7429 表征治疗诱导性与遗传性错配修复缺陷型超突变胶质瘤的空间肿瘤微环境 Characterizing the spatial tumor microenvironments of therapy-induced and hereditary mismatch-repair-deficient hypermutated gliomas Chae Yun (Kate) Cho, Bo Zhao, Lingqun Ye, Inés Martín-Barrio, Yonathan Lissanu, Kadir C. Akdemir
- 7430 7430 与NSCLC检查点阻断应答相关的前体耗竭型CD8⁺ T细胞的转录程序 Transcriptional programs of precursor-exhausted CD8⁺ T cells associated with checkpoint blockade response in NSCLC Ethan Daniel Littlestone, Md Roungu Ahmmad, Xiaoli Zhang
- 7431 7431 多发性骨髓瘤自体干细胞移植大剂量美法仑预处理后可测量残留病灶的代谢相关因素 Metabolic correlates of measurable residual disease following high dose melphalan conditioning for autologous stem cell transplant in multiple myeloma Qualia Hooker, Timothy Triche
- 7432 7432 受照射的ER阳性乳腺癌淋巴结的空间蛋白质谱分析提示淋巴结照射调节免疫功能 Spatial protein profiling of irradiated ER positive breast cancer lymph nodes suggests nodal irradiation modulates immune function Stephanie O. Dudzinski, Elizve N. Barrientos-Toro, Benjamin D. Smith, Simona F. Shaitelman, Sharia Hernandez, Alejandra Serrano, Khan Khaja, Larisa Kostousov, Wei Lu, Rensi Zacharia, Nathan Comeaux, Solis M. Luisa, Aysegul A. Sahin, Maria Gabriela Raso, Jing Wang, Karen Hoffman, Wendy A. Woodward
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- 7437 7437 通过空间微域和网络生物学解码肿瘤微环境异质性以预测免疫治疗结局 Decoding tumor microenvironment heterogeneity through spatial microdomains and network biology to predict immunotherapy outcomes A. Burak Tosun, Raymond Yan, Brian Falkenstein, Filippo Pullara, S. Chakra Chennubhotla
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- 7440 7440 通过空间转录组学表征转移性 TIME 揭示抗 CSF-1R 和免疫化疗后的独特细胞表型 Characterization of the metastatic TIME via spatial transcriptomics reveals unique cellular phenotypes post anti-CSF-1R and immuno-chemotherapy Diego Armando Pedroza, Sung Wook Kang, Xiang H.-F. Zhang, Bora Lim, Hyun-Sung Lee, Jeffrey M. Rosen
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- 7442 7442 通过激活利他性干细胞防御反应减轻癌症化疗诱导的加速衰老 Cancer chemotherapy-induced accelerated aging is mitigated by activation of the altruistic stem cell defense response Lekhika Pathak, Partha Jyoti Saikia, Upasha Sarmah, Rupam Das, Chayanika Das, Tulika Sarma, Bikul Das
- 7443 7443 低缺氧微环境和T细胞成熟受损驱动绝经前三阴性乳腺癌的免疫治疗耐药 Low hypoxia microenvironment and impaired T cell maturation drive immunotherapy resistance in premenopausal triple negative breast cancer Vidya Prasad Nimbalkar, Snijesh V P, Anupama CE, Mahalakshmi S, Annie Alexander, Rakesh Ramesh, Srinath BS, Jyothi S. Prabhu
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- 7445 7445 效应性调节性T细胞浸润、ARID1A状态与卵巢透明细胞癌的离体抗PD-1应答：来自高级别浆液性卵巢癌对照队列的启示 Effector regulatory T-cell infiltration, ARID1A status, and Ex Vivo anti-PD-1 response in ovarian clear cell carcinoma: Insights from a comparative high-grade serous ovarian cancer cohort Junsik Park, Eun Kyung Kim, Jung Chul Kim, Nari Kim, JooHyang Lee, Sunghoon Kim, Sang Wun Kim, Yong Jae Lee, Jung-Yun Lee
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