PO.TB10.09 · 肿瘤生物学
Functional and Spatial Regulation of Immune Evasion and Anti-Tumor Immunity
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- 7388 7388 Distinct immune crosstalk axes define the tumor microenvironment across EGFR mutation status in NSCLC by single-cell profiling Yoojin Kim, Hyunsu Kim, Kyungjong Lee, Bo Mi Ku, Hae-Ock Lee, Jinyong Kim, Hyun Ae Jung, Jong-Mu Sun, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn, Sehhoon Park
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- 7392 7392 A cancer cell-intrinsic PAR1/MALT1/PD-L1 signaling pathway drives immune evasion in triple-negative breast cancer Dong Hu, Prasanna Ekambaram, Zheqi Li, Linda Klei, Maria L. Beecher, Yi Liu, Zongyou Cai, John Little, Jeffrey A. Meridew, Jia-Ying Lee, E. Aubrey Thompson, Tullia C. Bruno, Lidija Covic, Seung-Oe Lim, Anushka Dongre, Heide L. Ford, Mien-Chie Hung, Adrian V. Lee, Steffi Oesterreich, Linda McAllister-Lucas, Peter C. Lucas
- 7394 7394 Cytokine-driven CD38 + HLA-DR + CD8 + T cells define a bystander program predicting poor prognosis in hepatocellular carcinoma Wei-Ting Ku, Chien-Hao Huang, Cheng-Heng Wu, Wei Teng, Po Ting Lin, Tsung-Han Wu, Jian-He Fang, Chan-Keng Yang, Yen-Chun Liu, Wen-Juei Jeng, Yung-Chang Lin, Chun-Yen Lin
- 7396 7396 Osteopetrosis-associated transmembrane protein1 modulates CD8⁺ T-cell responses during immunotherapy in hepatocellular carcinoma Yixin Chen, Jie Luo, Nanzhou Yu, Yu Zhang, Ming Zhu, Yuma Yang, Lanqi Gong, Xin-Yuan Guan
- 7397 7397 Intercellular transfer of hepatocellular carcinoma-derived RNAs via tunneling nanotubes educates macrophages and enhances antigen presentation Yutao He, Lin Wang, Zhitian Shi
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- 7407 7407 The NAT10-PBX1 ac4C axis disables MHC Class II antigen presentation to promote immune‑cold cholangiocarcinoma Kai Luo, Yuhan Fang, Yinzhao Chen, Yuting Zhao, Jialin Qu, Dong Shang, Caiming Xu, Guixin Zhang
- 7408 7408 Brca2- deficiency promotes increased cGAS-STING pathway activation and an immunosuppressive tumor immune microenvironment in prostate cancer Kimberly A. Rickman, Irena Q. Sun, Ramya Parameswaran, Xuxu Gou, Morgan E. Diolaiti, Harish N. Vasudevan, Alan Ashworth
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- 7410 7410 Antiviral therapy reverses CMV-induced oncogenic signaling and enhances NK cell cytotoxicity in glioblastoma with associated PD-L1 upregulation and iImmune modulation Vida Tajiknia, Wafik S. El-Deiry, Connor Purcell, Sean E. Lawler
- 7411 7411 Proteotranscriptomic dissection of breast cancer T cell states identifies CD103+ Tfh-derived cytotoxic CD4+ cells linked to immunotherapy response Ghamdan Al-Eryani, Sophie van der Leij, Etienne Masle-Farquhar, Alma Andersson, Kate Harvey, Sunny Wu, Tony Wang, John Reeves, Cindy Ma, Daniel L. Roden, Charles M. Perou, Nir Hacohen, Aziz Al’Khafaji, Mats Nilsson, Joakim Lundeberg, Marcel Batten, Simon Junankar, Alexander Swarbrick
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