PO.TB10.16 · 肿瘤生物学
Therapeutic Modulation of the Tumor Microenvironment: New Targets and Approaches 2
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- 7451 7451 整合bulk与单细胞转录组学揭示PARL作为线粒体调控因子与肺鳞状细胞癌的免疫代谢重编程及良好预后相关 Integrated bulk and single cell transcriptomics reveal PARL as a mitochondrial regulator associated with immunometabolic reprogramming and favorable prognosis in lung squamous cell carcinoma Jaber H. Jaradat, Zaid Alwarawrah, Laith Alomari, Anwaar Saeed, Azhar Saeed
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- 7456 7456 PCSK1和PCSK7协调免疫检查点以增强抗肿瘤免疫 PCSK1 and PCSK7 orchestrate immune checkpoints to amplify anti-tumor immunity Marta Martín-Bórnez, Chloé Porcheron, Geraldine Siegfried, Serge Evrard, John Creemers, Nabil Seidah, Simon Pernot, Abdel-Majid Khatib
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- 7458 7458 探讨OST4对卵巢癌肿瘤发生和免疫微环境的影响 Examining OST4's impact on tumorigenesis and immune microenvironment in ovarian cancer Mengyi Gu, Michelle K.y. Siu, Ruiqian Zhang, Luqi CHEN, Ling Shan HUNG, Kui Liu, Yuen Sheung Hextan Ngan, Haonan Lu, Annie NY Cheung, Karen K.l. Chan
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- 7460 7460 与突变型IL-2连接的逻辑门控T细胞衔接器用于更安全更有效的实体瘤免疫治疗 Logic-gated T cell engager linked with mutant IL-2 for safer and better effective solid tumor immunotherapy Yang-Xin Fu
- 7461 7461 诱导大规模凋亡（PRIMA-1MET）对卵巢癌细胞致瘤性趋化因子的抑制作用 Inhibitory effects of induction of massive apoptosis (PRIMA-1 MET ) on tumorigenic chemokines in ovarian cancer cells Audene B. Wilkinson, Deok-Soo Son
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- 7463 7463 靶向S100A7/RAGE驱动的Stat3/Serpin-E1信号用于转移性乳腺癌的免疫治疗 Targeting S100A7/RAGE-driven Stat3/Serpin-E1 signaling for immunotherapy in metastatic breast cancer Pratyusha Ghanta, Ajeet K. Verma, Cho-Hao Lin, Manish Charan, Ganesh R. Koshre, Tanisha Mukherjee, Wayne O. Miles, Sanjay Mishra, Ramesh Ganju
- 7464 7464 通过破坏nNOS/NO与COX-2之间的相互作用抑制干扰素-gamma刺激的黑色素瘤进展 Inhibiting interferon-gamma-stimulated melanoma progression by disrupting the crosstalk between nNOS/NO and COX-2 Anika Patel, Kate Alison Lozada, Moom Roosan, Basir Syed, Jennifer Totonchy, Amardeep Awasthi, Richard B. Silverman, Sun Yang
- 7465 7465 脱氧核糖环二核苷酸的化学调控STING激活型前药引发强效免疫激活和持久的抗肿瘤免疫 Chemically regulated STING-activating prodrugs of deoxyribose cyclic dinucleotides elicit robust immune activation and durable antitumor immunity Huimin Liu, Zhiqiang Xie, Kejia Xu, Rong Xiang, Shibo Li, Zhen Xi
- 7466 7466 Epiregulin驱动免疫抑制性TAM编程，并在结直肠癌中受miR-19a-3p负调控 Epiregulin drives immunosuppressive TAM programming and is negatively regulated by miR-19a-3p in colorectal cancer Ah Ran Yu, Ju Yeon Park, Jeong Eun Kang, Sang Hyuk Moon, Hey Kyung Hong, Yong Beom Cho
- 7467 7467 使用pH敏感荧光染料实时检测ADC内化动力学 Real-time detection of ADC internalization kinetics using a pH-sensitive fluorescent dye An Ouyang, Linlin Ma, Di Shi, Siwen Wang, Tianfu Zhang, Zhicheng Dong, YuehChun Hsieh
- 7468 7468 钙稳态调节因子GRIN2D激活癌症相关成纤维细胞导致促纤维增生并促进胰腺导管腺癌中中性粒细胞浸润以形成中性粒细胞胞外诱捕网 Calcium homeostasis modulator GRIN2D activates cancer‐associated fibroblast for desmoplasia and promotes neutrophil infiltration for neutrophil extracellular trap formation in pancreatic ductal adenocarcinoma Chi Hin Wong, Yip Kan Kwan, Ka-Fai To, Yangchao Chen
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- 7470 7470 揭示XPO6在鼻咽癌中的作用 Uncovering the role of XPO6 in nasopharyngeal carcinoma Ziye Lu, Ziyang Qi, Lanqi Gong, Yuma Yang, Jie Luo, Qin Liu, Xin-Yuan Guan
- 7471 7471 阻断弥漫型胃癌细胞与癌相关成纤维细胞之间异细胞黏附的化合物的鉴定与表征 Identification and characterization of compounds that block heterocellular adhesion between diffuse-type gastric cancer cells and cancer-associated fibroblasts Hideki Yamaguchi, Yuko Nagamura, Makoto Miyazaki
- 7472 7472 蒲公英甾醇通过靶向PTP1B/PKM2/NF-κB信号通路抑制H. pylori诱导的胃炎和胃癌 Taraxasterol suppresses H. pylori -induced gastritis and gastric cancer by targetingPTP1B/PKM2/NF-κB signaling pathway Liting Zhou
- 7473 7473 一种针对TNBC的新型双靶点策略:联合EZH2抑制与多巴胺D1受体激活以恢复免疫平衡 A novel dual-target strategy against TNBC: Combining EZH2 inhibition and dopamine D1 receptor activation to restore immune balance Rajni Kant Shukla, Kate Ormiston, Gautam Sarathy, Shivani Dhekne, Dionisia Marie Quiroga, Sanjay Gupta, Daniel G. Stover, Pierre Giglio, Christian Rolfo, Eswar Shankar
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- 7475 7475 葡萄籽原花青素提取物与水飞蓟水飞蓟素提取物的联合应用可累加性地减少THP-1来源的M2巨噬细胞向肺肿瘤微环境的募集 Combinations of grape seed procyanidin extract and milk thistle silymarin extract additively decrease recruitment of THP-1 derived M2 macrophages into the lung tumor microenvironment. Jenny T. Mao, Diego Oliva, Jessica Schilter, Lauren Rollin, Lily Jih
- 7476 7476 AOC1在调节卵巢癌肿瘤微环境和恶性表型中的作用 Role of AOC1 in modulating the ovarian cancer tumor microenvironment and malignant phenotype Sammy Ferri-Borgogno, Chun Wai (Oscar) Ng, Basant T. Gamal, Erin H. Seeley, Yadira Pacheco, Christopher D. Pacheco, Jared K. Burks, Samuel Mok
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