PO.MCB03.03 · 分子与细胞生物学
Tumor Cell Plasticity, Microenvironment, and Stress-Response Pathways
- 563 563 WEE1通过抑制GSK3β强化C-MYC驱动的致癌程序 WEE1 reinforces C-MYC driven oncogenic programs through GSK3ß inhibition Krishnapriya Thangaretnam, Islam MD Obaidul, Jialun Lyu, Zhenzhen Zhang, Lei Chen, Farah Ballout, Heng Lu, Dunfa Peng, Alexander I. Zaika, Wael El-Rifai, Zheng Chen
-
564 · PDF 克隆多样性驱动肺癌中的协同生长 Clonal diversity drives cooperative growth in lung cancer Yan Jennifer Gu, Salil Garg
-
565 · PDF 确立卵巢癌中化疗反应与Hippo-YAP信号的机制联系 Establishing the mechanistic link between chemotherapy response and Hippo-YAP signaling in ovarian cancer Jonathan C. Vose, Elizabeth I. Harper, Sheetal Kooduvalli, Joanne Kotelawala, Ashani Weeraratna, Jennifer M. Kavran
-
566 · PDF UVRAG-ITCH-ESCRT轴介导溶酶体"关闭开关"以抑制癌症中的NOTCH1信号 UVRAG-ITCH-ESCRT axis mediates a lysosomal off-switch dampening NOTCH1 signaling in cancer Behzad Mansoori, Zihan Zheng, Chintan Parekh, Chengyu Liang
-
567 · PDF SGK1可能是BRAF突变型黑色素瘤的治疗靶点 SGK1 may represent a therapeutic target in BRAF-mutant melanoma Boyd Griffiths, Camden VanTassell, Joshua Knight, Madison Hawkins, Landen Barnett, Katie Culver, Ashley Thompson-Chadwick, Sheri L. Holmen, Gennie Lynne Parkman
-
568 · PDF YAP1-IGFBP2轴作为胃癌转移的预测性生物标志物和治疗靶点 The YAP1-IGFBP2 axis as a predictive biomarker and therapeutic target in gastric cancer metastasis Emily Hancin, Hyun-Kyung Ko, Madeline B. Torres, Xiaodan Yao, Yibo Fan, Melissa Pool Pizzi, Shilpa S. Dhar, Francis Spitz, Generosa Grana, Jaffer A. Ajani, Shumei Song
- 569 569 乙酰胆碱诱导的YAP稳定化通过nAchR-alpha7/PI3K/PDPK1通路在缺氧条件下增强胰腺癌细胞的HIF-1信号 Acetylcholine-induced YAP stabilization enhances HIF-1 signaling under hypoxia via the nAchR-alpha7/PI3K/PDPK1 pathway in pancreatic cancer cells Yunmi Cho, Ha Hyeong Kim, Eun-Taex Oh
- 570 570 柔软的细胞外基质通过触发RNF146介导的AMOT降解和YAP/TAZ驱动的巨噬细胞衰老来协调胃癌进展 Soft extracellular matrix orchestrates gastric cancer progression by triggering RNF146-mediated AMOT degradation and YAP/TAZ-driven senescence in macrophages Guofei Deng, Yusheng Luo, Yuxi Pan, Xiaorong Lin, Yuzhi Zhang, Yuqing Lin, Fuhui Wang, Jiancheng Wang, Shuo Fang
-
571 · PDF 妊娠相关乳腺癌中WNT和Notch的串扰 WNT and Notch crosstalk in pregnancy-associated breast cancer Charles Moore, Wen-Cheng Chung, Shifa Khan, Keli Xu
-
572 · PDF 定义调控Hippo信号输出的DLG5-NUAK2-LATS1复合物 Defining a DLG5-NUAK2-LATS1 complex that regulates Hippo signaling output Youchen Song, Abiodun Ogunjimi, Siyuan Song, Jeffrey L. Wrana, Liliana Attisano
- 573 573 驱动前列腺癌进展的协同机制 Cooperative mechanisms driving prostate cancer progression Runhua Liu, Chao Zhang, Haiyan Yui, Lizhong Wang
-
574 · PDF 通过Hippo-YAP/TAZ-TEAD信号通路探索去势抵抗性前列腺癌的治疗易感性 Exploring the therapeutic vulnerability of castration-resistant prostate cancer via Hippo-YAP/TAZ-TEAD signaling Vandana Mohan, Sweaty Koul, Mousa Vatanmakanian, Santosh Lamichhane, Praveen K. Jaiswal, Hari K. Koul
-
575 · PDF STK40与CDK7在癌症进展中对YAP活性的协同调控 Cooperative regulation of YAP activity by STK40 and CDK7 in cancer progression Pei Yi Li, Yi Chin Chen, Feng Chiao Tsai
- 576 576 探究BMP信号作为子宫内膜癌治疗易感靶点的研究 Investigating BMP signaling as a therapeutic vulnerability in endometrial cancer Purva Vinayak Gade, Craig Ceol
-
577 · PDF Septin-9缺失引发癌细胞中桥粒蛋白连接定位缺陷 Defects in junctional localization of desmosomal proteins in cancer cells triggered by loss of Septin-9 Cate G. Lyerly, Zach N. Pierce, Adi Dara Dubash
-
578 · PDF Cyclin F在代谢应激过程中于非小细胞肺癌中的新兴作用 Emerging roles of Cyclin F in Non-small lung cell carcinoma during metabolic stress Rohini Tamang, Sanjeev Das, Sangeeta Choudhury
-
580 · PDF TPM4过表达改变分化型结肠上皮细胞的屏障完整性 TPM4 overexpression modifies differentiated colon epithelial cell barrier integrity Brenna Backus, Michael Papetti
- 581 581 FUT8介导的岩藻糖基化通过肿瘤-成纤维细胞相互作用促进结直肠癌生长和转移潜能 FUT8-mediated fucosylation promotes colorectal cancer growth and metastatic potential via tumor-fibroblast interactions Zimo Huang, Sree K. Kondapuram, Xiang Y. Zheng, Praveen Agrawal, Chaoyuan Kuang
- 582 582 破坏中心粒生物发生调控因子Cenpj通过p53依赖性DNA损伤修复和凋亡通路降低口腔癌易感性 Disruption of Cenpj, a centriole biogenesis regulator, diminishes oral cancer susceptibility through p53-dependent DNA-damage repair and apoptosis pathways Mousumi Bhattacharjee, Heena Dave, Rekha Jalandra, Radhika R. Gudi, Chenthamarakshan Vasu
-
583 · PDF Septin-9与Desmoglein-2结合并调控癌细胞中细胞间连接的强度 Septin-9 binds to Desmoglein-2 and controls cell-cell junction strength in cancer cells Michael W. Jaber, Emily G. Bernier, Adi Dara Dubash
-
584 · PDF sFRP1在黑色素瘤中的情境依赖性作用 Context-dependent roles of sFRP1 in melanoma Cierra Perron, Douglas Quilty, Farzaneh Afzali, Bianca Dauber, Tyler Cooper, Krista M. Vincent, Ivan Topisirovic, Lynne-Marie Postovit
- 585 585 双酚类物质经G蛋白偶联雌激素受体介导对MDA-MB-231乳腺癌细胞基因表达和细胞结局的影响 Effects of bisphenols on gene expression and cellular outcomes in MDA-MB-231 breast cancer cells mediated via G protein-coupled estrogen receptor Norman R. Estes, Cameron Sheeler
-
586 · PDF Pdcd4/mTORC2轴通过PFKFB3调控NSCLC中的糖酵解 Pdcd4/mTORC2 axis regulates glycolysis via PFKFB3 in NSCLC Elham Zokaei, Hsin-Sheng Yang, Qing Wang, Yanquan Zhang
-
587 · PDF 胆碱乙酰转移酶:暴露于烟草烟雾的肺腺癌患者中一个新的药物靶点 Choline Acetyltransferase: A novel drug target in lung adenocarcinoma patients who are exposed to tobacco smoke Piyali Dasgupta, Eric W. Bow, Krista Denning, Rama S. Gadepalli, John M. Rimoldi, Yi Charlie Chen, Sarah L. Miles
- 588 588 利用和厚朴酚增强5-氟尿嘧啶靶向胸苷酸合成酶(TYMS)治疗乳腺癌的疗效 Enhancing the efficacy of 5-fluorouracil in targeting thymidylate synthase (TYMS) for breast cancer treatment using honokiol Santosh K. Singh, Rajesh Singh
- 589 589 泛素特异性肽酶37(USP37)促进复制应激耐受以推动前列腺癌的肿瘤发生 Ubiquitin specific peptidase 37 (USP37) facilitate Replication stress tolerance to promote prostate cancer oncogenesis Suraja Kumar Das, Lakshay Malhotra, Gunjan Dagar, Teena Haritwal, Atul Batra, Ajaz A. Bhat, Mayank Singh
-
590 · PDF 细胞朊蛋白通过Wnt信号在乳腺癌中的作用 Role of cellular prion protein in breast cancer through Wnt signaling Parul Dubey, Manoj Kumar Mishra
-
591 · PDF 泛素连接酶HUWE1调控beta-catenin在WNT信号传导与细胞黏附功能之间的平衡 The ubiquitin ligase HUWE1 controls the balance between beta-catenin functions in WNT signaling and cell adhesion Caleb Kwame Sinclear, Joseph McKenna, Yalan Wu, Praveen Sonkusre, Andres M. Lebensohn
-
592 · PDF NSD2调控喉癌的细胞生长与致癌信号通路 NSD2 regulates cell growth and oncogenic signaling pathways in laryngeal carcinoma Ahmed Ismail, Iuliia Topchu, Amr Ismail, Tingting Zhang, Xu Jia, Peter Makhov, Yanis Boumber