PO.MCB09.03 · 分子与细胞生物学
Metabolite Control of Chromatin, Redox, and Cellular Stress Responses
- 535 535 急性睡眠剥夺重塑与癌症风险相关的代谢和线粒体通路 Acute sleep deprivation reprograms metabolic and mitochondrial pathways linked to cancer risk Behzad Varamini, Harrison Kim, Priscilla Kim, Madeline Lange, Stephanie Zeng, Jennifer Tudor
- 536 536 一种多重LC-MS/MS代谢物检测法,用于实现MTA协同型PRMT5抑制剂的患者分层和药效学监测 A multiplexed LC-MS/MS metabolite assay to enable patient stratification and pharmacodynamic monitoring for MTA-cooperative PRMT5 inhibitors Ethan Stancliffe, Ashima Mehta, Douglas Guzior, Adam Richardson, Tom Cohen, Kevin Cho, Gary Patti
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537 · PDF 组成型NRF2激活驱动过量半胱氨酸应激 Constitutive NRF2 activation drives excess cysteine stress Jennifer A. Brain, Anna-Lena B. G. Vigil, Kristian Davidsen, Ayaha Itokawa, Abby C. Jurasin, Hannah J. Kerbyson, Maximilian Kobiesa, Madeleine L. Hart, Sang Jun Yoon, Gina M. DeNicola, Lucas B. Sullivan
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539 · PDF 胆固醇触发染色质应激以驱动衰老和炎症 Cholesterol triggers chromatin stress to drive senescence and inflammation Yiqun Han, Yaobin Ouyang, Shouhai Zhu, Hangcheng Xu, Bin Chen, Ping Yin, Qin Zhou, Jinzhou Huang, Kuntian Luo, Zheming Wu, Huaping Xiao, Xinyi Tu, Jake A. Kloeber, Jiajun Jing, Xiaofeng Huang, Meng Xu Welliver, Zhenkun Lou, Robert Mutter
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540 · PDF 癌细胞在低脂质环境中对甲硫氨酸循环扰动敏感 Cancer cells are sensitive to methionine cycle perturbation in low-lipid environments Diya Lakshmi Ramesh, Keene L. Abbott, Ryan Elbashir, Edrees H. Rashan, Raphael Ferreira, Matthew G. Vander Heiden
- 541 541 102项包含差异表达钾通道(KCN)基因的癌症研究揭示了pH敏感性,并随机性地保留了一种拟议的由K+/H+启动的H+释放策略以实现pH逆转 102 Cancer studies including differentially expressed potassium channel (KCN) genes reveal pH sensitivity with stochastic preservation of a proposed K + /H + initiated H + release strategy for pH reversal Marie E. Beckner
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542 · PDF 一种新型一碳通路在癌症中生成核内SAM以进行染色质甲基化 A novel one carbon pathway generates nuclear SAM for chromatin methylation in cancer Tiziano Bernasocchi
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543 · PDF PSAT1表达在人类癌症中的普遍性和意义 Prevalence and significance of PSAT1 expression in human cancer Fiete Gehrisch, Hendrina Contreras, Maximilian Lennartz, Katharina Möller, Nathalia Gorbokon, Martina Kluth, Claudia Hube-Magg, Maria Christina Tsourlakis, Nina Schraps, Florian Viehweger, David Dum, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Patrick Lebok, Guido Sauter, Till S. Clauditz, Till Krech, Andreas H. Marx, Ronald Simon, Eike Burandt, Sarah Minner, Stefan Steurer, Ria Schlichter, Seyma Büyücek
- 544 544 解析铁氧还蛋白还原酶各种异构体在细胞存活和DNA损伤反应中的生物学功能 Dissecting the biological functions of various isoforms of ferredoxin reductase for cell survival and DNA damage response Kenichi Nakajima, Shakur Mohibi, Kyle Kenji Hong, Xinbin Chen, Jin Zhang
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545 · PDF PFAS介导的DRP1脱酰胺化将线粒体动力学与嘌呤生物合成相偶联 PFAS-mediated DRP1 deamidation couples mitochondrial dynamics to purine biosynthesis Xinchi Xie, Yongzhen Liu, Chao Qin, Jessica Carriere, Pinghui Feng