Tumor Suppressors

• 596 · PDF DDX3调控线粒体功能以抑制HCC进展 DDX3 modulates mitochondrial function to inhibit HCC progression Jun-Huan Huang, Heng-Yu Lin, Yi-Yuan Su, RU-TSUN MAI
• 597 · PDF CREBBP突变通过损害HDAC3乙酰化依赖的PTEN表达促进肿瘤生长 CREBBP mutation promotes tumor growth by impairing HDAC3 acetylation-dependent expression of PTEN Xiang Wang, Wenquan Hu, Qing Robert Miao
• 598 · PDF 在小鼠中进行CRISPR Cas9筛选以鉴定侵袭性人类淋巴瘤的肿瘤抑制因子 CRISPR Cas9 Screens in Mice to Identify Tumor Suppressors of Aggressive Human Lymphoma Vivian Morris, Julius Enssle, Ashok Kumar, Arnold Bolomsky, Moyi Li, Yandan Yang, Da Wei Huang, George Wright, Weihong Xu, Hong Zhao, James Phelan, Jagan Muppidi, Louis Staudt
• 599 · PDF AKT2缺失抑制PTEN缺失诱导的混合谱系肝脏恶性肿瘤，涉及TGFb-Notch-SOX9信号 AKT2 loss inhibits mixed lineage liver malignancy induced by PTEN loss involving TGFb-Notch-SOX9 signal Qi Tang, Yiwei Gu, Jingyu chen, Lina He, Ni Zeng, Shunan Hu, Slarve Ielyzaveta, Diala Alhousari, Guo Zhang, Zifei Xu, Phillip Nguyen, Gray Kanel, Shefali Chopra, Liyun Yuan, Bangyan L. Stiles
• 600 · PDF ZNF865作为癌症治疗的新型分子靶点 ZNF865 as a novel molecular target for cancer treatment Cansu Umran Tunc, Hamid Ghandehari, Robert Bowles
• 601 · PDF 翻译重编程破坏有丝分裂以驱动SMAD4缺陷型食管腺癌 Translational reprogramming disrupts mitosis to drive SMAD4-deficient esophageal adenocarcinoma Julia V. Milne, Ka Meng Wu, Sasha Witts, Eric Kusnadi, Kenji Fujihara, Katherine Papastratos, Maree Pechlivanis, Anna Trigos, Metta Jana, Luc Furic, Kaylene Simpson, David Liu, Cuong Duong, Wayne Phillips, Nicholas Clemons
• 602 · PDF p53免疫组化模式在1,515例头颈部鳞状细胞癌患者中的原发部位特异性分布及预后意义 Primary site specific distribution and prognostic significance of p53 immunohistochemistry patterns in 1,515 patients with head and neck squamous cell carcinoma Takane Watanabe, Yoshitaka Honma, Toshihide Ueno, Yukiko Nakamura, Eijitsu Ryo, Hideaki Takahashi, Akiko Mori, Yuko Kubo, Mitsuhiko Katoh, Kohtaro Eguchi, Azusa Sakai, Toshihiko Sakai, Chihiro Fushimi, Go Omura, Kenji Okami, Yasushi Yatabe, Hiroyuki Mano, Seiichi Yoshimoto, Taisuke Mori
• 603 · PDF p53 R181残基处的变异导致p53 DNA结合协同性丧失，但保留线粒体相关的凋亡功能 Variation at the R181 residue of p53 confers loss of p53 DNA binding cooperativity with the retention of mitochondrial-associated apoptosis Renyta Moses, Alexandra Indeglia, Alison Schwartz-Levine, Ryan Hausler, Gregory Kelly, Sven Miller, Isabel Anez, Melissa Heller, Rosella Delgado, Caitlin Orr, Wendy Kohlmann, Anne Naumer, Jennie Vagher, Sophie H. Cahill, Luke D. Maese, John Karanicolas, Judy E. Garber, Maureen E. Murphy, Kara N. Maxwell
• 604 · PDF 第二位点拯救突变体作为揭示p53癌症突变体重激活机制的工具 Second site rescue mutants as tools to uncover reactivation mechanisms of p53 cancer mutants Fiona Law, Zane Norman, Mark Villamil, Peter Kaiser
• 605 · PDF 绘制Li-Fraumeni综合征中的杂合性缺失以揭示肿瘤发生的早期分子驱动因素 Mapping loss of heterozygosity in Li-Fraumeni Syndrome to uncover early molecular drivers of tumorigenesis Hailey Stack, Ashby Kissoondoyal, David Malkin
• 606 · PDF DACH1传递异构体特异性的抑癌功能 DACH1 conveys isoform specific tumor suppressor functions Kenneth A. Iczkowski, Zhiping Li, HIdetoshi Mori, Danni Li, Samiha Nasser, Csaba Kerepesi, Andras Benczur, Hallgeir Rui, Ritika Harish, Xuanmao Jiao, Fred Saad, Richard G. Pestell
• 607 · PDF NF1缺陷的HER2阳性乳腺癌在有丝分裂和药理学应激下微管晶格损伤的定量分析 Quantitative analysis of microtubule lattice damage in NF1-deficient HER2-positive breast cancer under mitotic and pharmacological stress Eleonora Messuti, Alessia Castiglioni, Simona Rodighiero, Ambra Dondi, Bruno Achutti Duso, Luca Mazzarella
• 608 · PDF Ccn6缺失与EZH2过表达协同作用诱导化生性乳腺癌的肉瘤样分化 Ccn6 loss cooperates with EZH2 overexpression to induce sarcomatoid differentiation in metaplastic breast carcinoma Maria E. Gonzalez, Ahmad Eido, Kendall Miller, Celina G. Kleer
• 609 · PDF 探究NISCH在乳腺癌中的抑癌功能及调控机制 Investigating tumor suppressor function and regulatory control of NISCH in breast cancer Abigail E. Rink, Suresh K. Alahari
• 610 · PDF 昼夜节律调节因子PER2缺失通过免疫抑制增强乳腺癌易感性与进展 Lack of circadian regulator PER2 enhances breast cancer susceptibility and progression via immunosuppression Yixin Duan, Helen Zhang, Hongyong Zhang, Jie Huang, Xiong Zhang, Aris Alexandro, Dake Hao, Jonathan I. Berg, Ming Fan, Yili Wang, Loning Fu, Hong-Wu Chen, Jian Jian Li
• 611 · PDF NSD1-AURKA-SETD2轴在透明细胞肾细胞癌中造成新的有丝分裂脆弱性 NSD1-AURKA-SETD2 axis creates novel mitotic vulnerabilities in clear cell renal cell carcinoma Manga Motrapu, Ashley Boice, Richard Han, Xiaoli Wang, Pratim Chowdhury, Sung Jung, Ruhee Dere
• 612 · PDF 一条新的调控通路作为间皮瘤恶性转化的驱动因素 A novel regulatory pathway as a driver of malignant transformation in mesothelioma. Flavia Novelli, Lydia Giannakou, Jin Hee Kim, Joelle S. Suarez, Cristina Favaron, Qian Wang, Angela Bononi, Michele Carbone, Haining Yang
• 613 613 Bap1驱动的软组织肉瘤:小鼠建模与治疗策略 Bap1 driven soft tissue sarcomas: Mouse modeling and therapeutic strategies Xingliang Liu, William Haugh, Bryan R. Bell, Jianguo Huang
• 615 615 AMBRA1介导的核质控制促进肝癌的早期发生 AMBRA1-mediated nucleocytoplasmic control promotes early onset of liver cancer Yimiao He, Linglin Liu, Yunong Xie, Minghe Zhang, Yan Liu, Man Tong
• 616 · PDF 理解错义与无义:肿瘤细胞劫持突变诱导的抑癌因子错误定位 Making sense of mis-sense and non-sense: Tumor cells hijack mutation-induced mis-localization of tumor suppressors Murali Dharan Bashyam, Sanjana Sarkar, Jimlee Saikia
• 618 · PDF 评估胆碱乙酰转移酶(ChAT)在T细胞恶性肿瘤中的作用 Evaluating the role of choline acetyltransferase (ChAT) in T cell malignancies Arwa Hilal, Maureen A. Cox, Michael St. Paul, Tak W. Mak

在会议检索中浏览本分会场