Tumor Suppressors

• 596 · PDF DDX3 modulates mitochondrial function to inhibit HCC progression Jun-Huan Huang, Heng-Yu Lin, Yi-Yuan Su, RU-TSUN MAI
• 597 · PDF CREBBP mutation promotes tumor growth by impairing HDAC3 acetylation-dependent expression of PTEN Xiang Wang, Wenquan Hu, Qing Robert Miao
• 598 · PDF CRISPR Cas9 Screens in Mice to Identify Tumor Suppressors of Aggressive Human Lymphoma Vivian Morris, Julius Enssle, Ashok Kumar, Arnold Bolomsky, Moyi Li, Yandan Yang, Da Wei Huang, George Wright, Weihong Xu, Hong Zhao, James Phelan, Jagan Muppidi, Louis Staudt
• 599 · PDF AKT2 loss inhibits mixed lineage liver malignancy induced by PTEN loss involving TGFb-Notch-SOX9 signal Qi Tang, Yiwei Gu, Jingyu chen, Lina He, Ni Zeng, Shunan Hu, Slarve Ielyzaveta, Diala Alhousari, Guo Zhang, Zifei Xu, Phillip Nguyen, Gray Kanel, Shefali Chopra, Liyun Yuan, Bangyan L. Stiles
• 600 · PDF ZNF865 as a novel molecular target for cancer treatment Cansu Umran Tunc, Hamid Ghandehari, Robert Bowles
• 601 · PDF Translational reprogramming disrupts mitosis to drive SMAD4-deficient esophageal adenocarcinoma Julia V. Milne, Ka Meng Wu, Sasha Witts, Eric Kusnadi, Kenji Fujihara, Katherine Papastratos, Maree Pechlivanis, Anna Trigos, Metta Jana, Luc Furic, Kaylene Simpson, David Liu, Cuong Duong, Wayne Phillips, Nicholas Clemons
• 602 · PDF Primary site specific distribution and prognostic significance of p53 immunohistochemistry patterns in 1,515 patients with head and neck squamous cell carcinoma Takane Watanabe, Yoshitaka Honma, Toshihide Ueno, Yukiko Nakamura, Eijitsu Ryo, Hideaki Takahashi, Akiko Mori, Yuko Kubo, Mitsuhiko Katoh, Kohtaro Eguchi, Azusa Sakai, Toshihiko Sakai, Chihiro Fushimi, Go Omura, Kenji Okami, Yasushi Yatabe, Hiroyuki Mano, Seiichi Yoshimoto, Taisuke Mori
• 603 · PDF Variation at the R181 residue of p53 confers loss of p53 DNA binding cooperativity with the retention of mitochondrial-associated apoptosis Renyta Moses, Alexandra Indeglia, Alison Schwartz-Levine, Ryan Hausler, Gregory Kelly, Sven Miller, Isabel Anez, Melissa Heller, Rosella Delgado, Caitlin Orr, Wendy Kohlmann, Anne Naumer, Jennie Vagher, Sophie H. Cahill, Luke D. Maese, John Karanicolas, Judy E. Garber, Maureen E. Murphy, Kara N. Maxwell
• 604 · PDF Second site rescue mutants as tools to uncover reactivation mechanisms of p53 cancer mutants Fiona Law, Zane Norman, Mark Villamil, Peter Kaiser
• 605 · PDF Mapping loss of heterozygosity in Li-Fraumeni Syndrome to uncover early molecular drivers of tumorigenesis Hailey Stack, Ashby Kissoondoyal, David Malkin
• 606 · PDF DACH1 conveys isoform specific tumor suppressor functions Kenneth A. Iczkowski, Zhiping Li, HIdetoshi Mori, Danni Li, Samiha Nasser, Csaba Kerepesi, Andras Benczur, Hallgeir Rui, Ritika Harish, Xuanmao Jiao, Fred Saad, Richard G. Pestell
• 607 · PDF Quantitative analysis of microtubule lattice damage in NF1-deficient HER2-positive breast cancer under mitotic and pharmacological stress Eleonora Messuti, Alessia Castiglioni, Simona Rodighiero, Ambra Dondi, Bruno Achutti Duso, Luca Mazzarella
• 608 · PDF Ccn6 loss cooperates with EZH2 overexpression to induce sarcomatoid differentiation in metaplastic breast carcinoma Maria E. Gonzalez, Ahmad Eido, Kendall Miller, Celina G. Kleer
• 609 · PDF Investigating tumor suppressor function and regulatory control of NISCH in breast cancer Abigail E. Rink, Suresh K. Alahari
• 610 · PDF Lack of circadian regulator PER2 enhances breast cancer susceptibility and progression via immunosuppression Yixin Duan, Helen Zhang, Hongyong Zhang, Jie Huang, Xiong Zhang, Aris Alexandro, Dake Hao, Jonathan I. Berg, Ming Fan, Yili Wang, Loning Fu, Hong-Wu Chen, Jian Jian Li
• 611 · PDF NSD1-AURKA-SETD2 axis creates novel mitotic vulnerabilities in clear cell renal cell carcinoma Manga Motrapu, Ashley Boice, Richard Han, Xiaoli Wang, Pratim Chowdhury, Sung Jung, Ruhee Dere
• 612 · PDF A novel regulatory pathway as a driver of malignant transformation in mesothelioma. Flavia Novelli, Lydia Giannakou, Jin Hee Kim, Joelle S. Suarez, Cristina Favaron, Qian Wang, Angela Bononi, Michele Carbone, Haining Yang
• 613 613 Bap1 driven soft tissue sarcomas: Mouse modeling and therapeutic strategies Xingliang Liu, William Haugh, Bryan R. Bell, Jianguo Huang
• 615 615 AMBRA1-mediated nucleocytoplasmic control promotes early onset of liver cancer Yimiao He, Linglin Liu, Yunong Xie, Minghe Zhang, Yan Liu, Man Tong
• 616 · PDF Making sense of mis-sense and non-sense: Tumor cells hijack mutation-induced mis-localization of tumor suppressors Murali Dharan Bashyam, Sanjana Sarkar, Jimlee Saikia
• 618 · PDF Evaluating the role of choline acetyltransferase (ChAT) in T cell malignancies Arwa Hilal, Maureen A. Cox, Michael St. Paul, Tak W. Mak

在会议检索中浏览本分会场