PO.PR02.01 · 预防研究
Experimental Chemoprevention and Interception: Data and Tools
- 942 942 用于癌症预防与阻断的天然产物发现的靶点验证及高通量筛选检测法开发 Target validation and high-throughput screening assay development for natural product discovery for cancer prevention and interception Yurong Song, Brandon Somerville, Kajal Biswas, Karim Baktiar, Liankun Song, Sara Sanders, Tanja Grkovic, Ligia A. Pinto, Ana Catarina Menezes, Paul P. Liu, Matthew J. Hart, Chinthalapally V. Rao, Shugeng Cao, Xin Chen, Xu Wu, Xiaolin Zi, Mark J. Henderson, Barry R. O'Keefe, Altaf Mohammed, Robert H. Shoemaker
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- 944 944 EPA与萘普生联合可阻止iCAF极化并减轻与Pirc肿瘤发生相关的炎症 The combination of EPA and Naproxen prevents iCAF polarization and attenuates inflammation associated with Pirc tumor development Niti Jani, Ryan Beach, Michael Martinez, Shizuko Sei, Vignesh Gunasekharan, Daniel W. Rosenberg
- 945 945 利用OXPHOS抑制剂对源自癌症干细胞的三阴性乳腺癌进行化学预防 Chemoprevention of triple-negative breast cancer originating from cancer stem cells using OXPHOS inhibitors Esra Akkus, Cemile Uslu, Mert Güngör, Beyza Şimbil, Elif Uzun, Etna Abad, Alex Lyakhovich
- 946 946 腊肠树（Cassia fistula L.）树皮氯仿部位的脂质体包封增强了在艾氏腹水癌小鼠模型中的抗癌疗效 Liposomes encapsulated chloroform fraction of Cassia fistula L. bark enhances anticancer efficacy in ehrlich ascites carcinoma mice model Satwinderjeet Kaur, Rasdeep Kour
- 947 947 以天然催乳药天门冬（Asparagus racemosus，Shatavari根提取物）调节乳腺结构及其对三阴性乳腺癌（TNBC）肿瘤发生的影响 Mammary gland architectural modulation with a natural galactagogue Asparagus racemosus (Shatavari root extract) and its impact against triple negative breast cancer (TNBC) tumorigenesis Md. Imtiazul Kabir, Robin Kumar, Lakshmi Sai Pratyusha Bugata, Komal Raina
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- 953 953 Rheum webbianum 通过调节 Wnt/beta-catenin 和 TGF-beta 信号通路对结直肠癌的化学预防作用：来自体外和体内研究的见解 Chemopreventive effects of Rheum webbianum against colorectal cancer via modulation of Wnt/beta-catenin and TGF-beta signaling: Insights from in-vitro and in-vivo studies Umer Majeed Khaja, Reena Singh, Showkat Ahmad Ganie
- 954 954 达比加群酯通过重塑免疫微环境增强抗 CTLA4 抗体在 MyC-CaP 细胞同基因小鼠模型中的抗肿瘤作用 Dabigatran etexilate potentiates the anti-tumor effects of anti-CTLA4 antibody through remodeling the immune microenvironment in a syngeneic mouse model of MyC-CaP cells Liankun Song, Matthew Gozon, Andrewtrung Le, Jun Xie, Xiaolin Zi
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- 956 956 通过下调 Myc 和 E2F 靶基因并诱导自噬性凋亡，重新利用达比加群酯以改善前列腺癌的预防和治疗 The repurpose of dabigatran etexilate for improving prostate cancer prevention and treatment through down-regulating Myc and E2F target genes and inducing autophagic apoptosis Guanxing Zhai, Vinh Le, Liankun Song, Yixi “Michael” Wu, Xiaolin Zi
- 958 958 用于评估靶向 EGFR L858R/T790M 和 EGFR L858R/T790M/C979S 耐药突变的疗法的新型同基因 NSCLC 模型 Novel syngeneic models for evaluating therapies targeting EGFR L858R/T790M and EGFR L858R/T790M/C979S resistance mutations in NSCLC Lei Ci, Kai Zhou, Jiangyan Liu, Ruilin Sun
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- 962 962 苯乙醛通过内质网应激诱导凋亡并增强5-FU对结直肠癌的治疗效果 Phenylacetaldehyde induces apoptosis through endoplasmic reticulum stress and potentiates the effect of 5-FU treatment in colorectal cancer Sylvain Ferrandon, Cheng Kong, sara soltani tehrani, Joseph Fedro, Rami-James Aoun, Zeneng Wang, Chureeporn Chitchumroonchokchai, Huanlong Qin, Steve Clinton, Matthew F. Kalady
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- 964 964 用于结直肠癌预防和治疗动物疗效试验的加速型Pirc大鼠模型 Accelerated Pirc rat model for animal efficacy trials for prevention and treatment of colorectal cancer Rashim Singh, Vesna Tumbas Saponjac, Trang Le Nu Huyen, Jie Yang, Jie Chen, Taijun Yin, Songpol Srinual, Ming Hu
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