PO.TB07.01 · 肿瘤生物学
Stem Cell Plasticity and Lineage Reprogramming in Cancer
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- 825 825 急性髓系白血病（AML）和多发性骨髓瘤（MM）患者的骨髓可用于评估新型抗体药物偶联物（ADC）的靶点表达及靶向疗效 Bone marrow from acute myeloid leukemia (AML) and multiple myeloma (MM) patients can be used to evaluate target expression and on-target efficacy for novel antibody drug conjugates (ADCs) Aisha Mergaert, Coranna Akdemirbey, Mariah Suchan, Tara Murray, Emer Clarke
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- 827 827 肌动蛋白细胞骨架调控可重编程耐药性GBM球体和GSC，在体外和体内增强对IR和temozolomide的应答 Actin cytoskeleton modulation reprograms resistant GBM spheroids and GSCs, enhancing response to IR and temozolomide in vitro and in vivo Yuli Thamires Magalhães, Viktor Kalbermatter Boell, Letícia Ramos Molica, Donna Joe, Fabio Luis Forti
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- 829 829 造血干细胞（HSC）浸润与细胞增殖呈负相关，与更好的患者生存相关，而新辅助化疗导致的HSC减少与乳腺癌的不良生存相关 Infiltration of hematopoietic stem cells (HSC) is associated inversely with cell proliferation, with better patient survival, and its reduction by neoadjuvant chemotherapy relates with poor survival in breast cancer Masanori Oshi, Rongrong Wu, Li Yan, Takashi Ishikawa, Itaru Endo, Kazuaki Takabe
- 831 831 组织转谷氨酰胺酶（TG2）与CD24之间的功能性串扰增强高级别浆液性卵巢癌的癌症干细胞特征和治疗耐药性 The functional crosstalk between tissue transglutaminase (TG2) and CD24 enhances cancer stem cell traits and therapy resistance in high grade serous ovarian cancer Rohit Pravin Nagare, Habeebunnisa Begum, Ben Wamba, Jogender Tushir-Singh, Fabrizio Pin, Salvatore Condello
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- 839 839 使用Pala单细胞分选仪对iPSC进行单细胞克隆可保持克隆干性和细胞活力，适用于高通量细胞系工程工作流程 Single cell cloning iPSCs with the Pala single cell sorter preserves colony stemness and cell viability for high-throughput cell line engineering workflows Bhamini Purandare, Francisco Ramirez, Ryan McComb, Chris Heger
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- 845 845 肿瘤相关间充质干细胞在胃肠道肿瘤腹膜播散的高氧化磷酸化区域聚集 Tumor-associated mesenchymal stem cells accumulate in high oxidative phosphorylation regions of peritoneal dissemination in gastrointestinal cancers Nobuhiko Kanaya, Yu Mikane, Shinji Kuroda, Eri Takeda, Makoto Matsumoto, Kosuke Yunoki, Yudai Mimata, Hitoshi Minagi, Tetsuya Katayama, Daisuke Kadowaki, Masashi Hashimoto, Yoshihiko Kakiuchi, Shunsuke Kagawa, Hiroshi Tazawa, Toshiyoushi Fujiwara
- 846 846 诱导多能干细胞(iPSCs)可诱发功能性细胞毒性T细胞应答的证据:为iPSC来源的癌症疫苗铺平道路 Evidence of functional cytotoxic T-cell responses to induced pluripotent stem cells (IPSCs): Paving the way for IPSC-derived cancer vaccines Valentine Feyants, Catherine Martel, Christophe Desterke, Mequa Maatoug, Diana Chaker, Ali G. Turhan, Annelise Bennaceur Griscelli, Frank Griscelli
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- 848 848 通过表型和代谢适应对乳腺癌转移的氧化还原调控 Redox regulation of breast cancer metastasis via phenotypic and metabolic adaptation Rachel Hazan, Viney Kumar, Outhiriaradjou Benard, premprashant chaudhary, mahaldeep kaur, Ian Myles, Bethesda, Larry Norton
- 850 850 SOX9和SEMA7A调控产后乳腺上皮细胞可塑性及其对产后乳腺癌的意义 SOX9 and SEMA7A regulate epithelial cell plasticity in the postpartum mammary gland with implications for postpartum breast cancer Lauren M. Cozzens, Brendan Hinckley, Sonali Jindal, Virginia F. Borges, Pepper Schedin, Traci Renae Lyons
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