PO.MCB09.01 · 分子与细胞生物学
Metabolic Regulation in Breast and Gynecologic Cancers
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2008 · PDF Fasting induces ferroptosis by modulating lipid metabolism in breast cancer Claudio Vernieri, Giovanni Fucà, Francesca Ligorio, Laura Tronci, Paola A. Corsetto, Giulia Salvadori, Arta Ajazi, Antonino Belfiore, Andrea Vingiani, Beatrice Cantarelli, Mattia Pavani, Keagile Bati, Lorenzo Drufuca, Saverio Minucci, Pagani Massimiliano, Filippo de Braud, Pruneri Giancarlo, Angela Bachi, Marzia Santamaria
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2009 · PDF Targeting metabolic vulnerabilities in basal-like breast cancer Amanda Linke, Kevin Mott, Felix Olivares, Michael East, Chengheng Liao, Qing Zhang, Gary L. Johnson, Charles M. Perou
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2010 · PDF Ovarian cancer drives mitochondrial dysfunction via WT1 in tumor associated stroma Roja Baruwal, Huda Issa Atiya, Paige Matusiak, Angelina Li, Swathi Suresh, Geyon Garcia, Benjamin K. Johnson, Hui Shen, Leonard Frisbie, Lan G. Coffman
- 2011 2011 Integrin alpha6beta4 stimulates glucose metabolism and NAD(H) production needed to drive invasive growth of triple negative breast cancer cells Yiming Sheng, Parvarnee A. Karimpour, Andrew Elliott, Jayla L. Fenderson, Teresa A. Cassel, Penghui Lin, Richard M. Higashi, Andrew N. Lane, Teresa W. M. Fan, Min Chen, Kathleen L. O'Connor
- 2012 2012 Spatial proteomic profiling of metabolic and cell signaling heterogeneity in breast cancer tumor microenvironment using imaging mass cytometry Qanber Raza, Nick Zabinyakov, Liang Lim, Christina Loh
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2013 · PDF Mitochondrial protein translation supports metabolic rewiring of chemo-refractory triple negative breast cancer Mariah Joy Berner, Steven W. Wall, Mokryun L. Baek, Audra Lane, Allison S. Greer, Karen Wang, Lacey E. Dobrolecki, Bing Zhang, Jonathan T. Lei, Michael T. Lewis, Gloria Vittone Echeverria
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2014 · PDF Metabolic adaptations of obesity-accelerated breast cancer. Amandine Chaix, Keren I. Hilgendorf, Gregory S. Ducker, Edgar J. Hernandez
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2015 · PDF Beta-hydroxybutyrate alters one-carbon and branched-chain amino acid metabolism in glucose-restricted ER+ breast cancer cells Cynthia Cheung, Natalija Glibetic, Rylee Maldonado, Tia Skaggs, Scott Bowman, Louise Torres, Katelynn A. Perrault Uptmor, Michael Weichhaus
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2016 · PDF Metabolic and inflammatory crosstalk underlying cancer-related fatigue (CRF) in a mouse model of breast cancer (BC) Abigail A. Koomson, Susana C. B. Nakandakari, Andin Fosam, Rosalie M. Grijalva, Rachel J. Perry
- 2017 2017 Time restricted eating potentiates chemotherapy in obesity-driven breast cancer mouse models Manasi Das, Yunpeng Yang, Isabella Maranan, Yanting Wang, Liping Zeng, Samantha Lu, Nicholas Webster
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2018 · PDF Investigating the role of Wnt/planar cell polarity signaling in the reprogramming of energy metabolism in breast cancer Liliana Loza Sanchez, Kacey VanderVorst, Kermit L. Carraway
- 2019 2019 Comparison of non-metastatic and metastatic breast cancer cell and lipid droplet proteomes Chaylen Andolino, Kimberly K. Buhman, Dorothy Teegarden
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2020 · PDF Fatty acid metabolism supports survival in normoxia and migration upon reoxygenation in lung-metastasizing breast cancer cells Marjorie Anne Layosa, Morgan Conrad, Chaylen Jade Andolino, Michael K. Wendt, Stephen D. Hursting, Dorothy Teegarden
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2022 · PDF Tryptophan metabolites drive ferroptosis resistance in triple-negative breast cancer cells Jamshid Motalebzadeh, Hossein Anani, Chloe Thompson-Peach, Theresa Hickey, Lisa Butler, Nirmal Robinson, Daniel Thomas
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2023 · PDF Tryptophan and serine metabolic axis reveals novel therapeutic vulnerabilities in triple-negative breast cancer Jamshid Motalebzadeh, Hossein Anani, Chloe Thompson-Peach, Theresa Hickey, Lisa Butler, Nirmal Robinson, Daniel Thomas
- 2025 2025 Zinc promotes aerobic glycolysis in breast cancer by promoting PKM2 dimerization and nuclear localization Wenyou He, Jiali Xu, Yihuizhi Zhang, Weijian Ding, Xinyu Chen, Yirui Ye, Linyue Li, Baotong Zhang, Siyuan Xia
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2026 · PDF Scd1 overexpression in cancer-associated adipocytes drives breast cancer development and metastasis Zander Esh, Pascal Naef, Justice Williams, Johnny Le, Gautham Prabhakar, Jacob Insua Rodriguez, Hannah Savage, Ayisha Bushra, Cholsoon Jang, Kai Kessenbrock
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2027 · PDF ATP citrate lyase fuels lipid storage to support triple negative breast cancer chemoresistance Katherine E. Pendelton, Mokryun L. Baek, Mariah J. Berner-Wu, Steven W. Wall, Audra Lane, Jonathan T. Lei, Iqbal Mahmud, Lin Tan, Lacey E. Dobrolecki, Philip L. Lorenzi, Michael T. Lewis, Blake R. Rushing, Gloria V. Echeverria
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2028 · PDF Hyperlipidemia drives tumor growth in a mouse model of obesity-accelerated breast cancer growth Renan Fudoli Lins Vieira, Sawyer Sanchez, Menusha Arumugan, Peyton Mower, Meghan Curtin, Abigail Jackson, Jillian Wright, Alexis Bowles, Gregory S. Ducker, Keren Hilgendorf, Amandine Chaix
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2029 · PDF Regulation of metabolic and stress adaptation in triple-negative breast cancer Emilia F. Carlo, Columba de la Parra, Erna Mitaishvili, Blessing Ukandu
- 2030 2030 Differential impact of metformin based prevention and therapeutic strategies on aberrant metabolic signals/ molecular signatures associated with triple negative breast cancer (TNBC) during high fat/ high fructose diet feeding Md. Imtiazul Kabir, Robin Kumar, Lakshmi Sai Pratyusha Bugata, M. Nurul Islam, Sanjida Afroz Mitu, Komal Raina
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2031 · PDF Reproducible serum metabolomics drives biomarker discovery in ovarian cancer Rachel Culp-Hill, Brendan Giles, Mattie Goldberg, Robert A. Law, Enkhtuya Radnaa, Shannon Kilkenny, Maria Wong, Connor Hansen, Benjamin G. Bitler, Kian Behbakht, Vuna Fa, Abigail McElhinny
- 2032 2032 MEX3A sustains mitochondrial integrity and metabolic resilience to drive ovarian clear cell carcinoma progression and liver colonization Priyanka Vinothkumar, Pei-Yi Lin, Li-Tzu Cheng, Chen-Hsin Albert Yu, Pang-Hung Hsu, Yu-Chi Chou, Wendy W. Hwang-Verslues
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2033 · PDF LSR suppresses ferroptosis through alpha-tocopherol uptake and promotes tumor growth in gynecological cancers Masashi Akada, Kosuke Hiramatsu, Yoshikazu Nagase, Tatsuo Masuda, Mamoru Kakuda, Satoshi Nakagawa, Tadashi Iwamiya, Shinya Matsuzaki, Michiko Kodama
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2034 · PDF H6PD as a metabolic target of DAP5 regulating NADPH homeostasis in TNBC Blessing Ukandu, Erna Mitaishvili, Emilia CARLO, Columba de la Parra
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2035 · PDF Cell density drives glutamine synthesis in fibroblast-like cells in the tumor microenvironment Lisa Shakachite, Natalya N. Pavlova
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2036 · PDF Post-transcriptional regulation of cancer by a metabolic pathway: modulation of HuR by the mevalonate pathway Mana Heidari, Raymond J. Hohl
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2037 · PDF Engineering multiplexed NRF2 reporters to decipher single cell oscillations in real time Naurisha Kapoor, Yasemin Ceyhan Ozdemir, James V. Alvarez