Metabolic and Transcriptional Control of Cancer Stem Cell Plasticity

• 2182 Upregulation of mitochondrial sirtuins in prostate cancer stem-like cells Shiv Verma, Leah Tharian, Jason A. Mears, Sanjay Gupta
• 2183 · PDF FABP4 functions as a novel cancer stem cell marker in triple-negative breast cancer Huiyi Feng, Jinquan Xia, Fuhua Zhong, Yinghuan Cen, Lu Jiang, Pan Zhao, Lin Gao, Chang Zou
• 2184 · PDF Defining cancer initiating cells and their vulnerabilities in renal cell carcinoma Zohreh Mehrjoo, Hellen Kuasne, Ariel M. Aguirre, Ozge Saatci, Ali Shahini, Matthew G. Annis, Anne-Marie N. Fortier, Tianyuan Lu, Larisa M. Soto, Hong Zhao, Dongmei Zuo, Virginie Pilon, Matthew Dankner, Tamiko Nishimura, Kevin Petrecca, Jonathan D. Spicer, Peter Siegel, Simon Tanguay, Hamed S. Najafabadi, Sahin Ozgur, Morag Park, Yasser Riazalhosseini
• 2185 · PDF Trem1 sustains liver cancer stemness in hepatocellular carcinoma Ashwin Ajith, Arsha Sreekumar, Kanza Mamouni, Anatolij Horuzsko
• 2186 Galangin effectively inhibits the proliferation and stemness characteristics of liver cancer stem cells by knocking down the expression of TINCR. Amira S. Fyala, Mohamed M. H Elkewedi, Ahmed S. Sultan
• 2187 · PDF Direct regulation of the cancer stemness by eIF4A1 in triple-negative breast cancer Azeezat Oluwatobiloba Osikoya, Shobhit Srivastava, David Terrero, Dayanidhi Raman
• 2188 Integrative transcriptomic profiling and flow cytometry analysis of AML PDX models identify purine-pyrimidine metabolic dependency shared in LSCs and blasts Kangsan Kim, Haiming Xu, Geoff Nelson, Tim Nieuwenhuis, Huiyun Liu, Justine Roderick-Richardson, Jessie Hao-ru Hsu, Brandon Willis, Lisa Drew, Omid Tavana
• 2189 · PDF Metabolic control of pancreatic cancer stemness through PDK3 dependent SOX2 lactylation Neelanjana Gayen, Nivedeta Krishna Kumar, Ayoola O. Ogunleye, Palanisamy Nallasamy, Venkatesh Varadharaj, Saravanakumar Marimuthu, Surinder K. Batra, Moorthy P. Ponnusamy
• 2190 · PDF Trib3 identified as a key therapeutic target for pancreatic cancer stem cells Nirjhar M. Aloy, Kyle McAndrews, Adam Zulli, Kathryn Baldwin, Kristine Von Maltzan, Sarah Thayer
• 2191 · PDF NQO1 inhibits FBXL14-dependent SNAIL degradation to promote EMT-mediated stemness in colorectal cancer cells Ha Gyeong Kim, Yunmi Cho, Eun-Taex Oh
• 2192 SLFN5 mediates liquid-to-solid phase transition of NOTCH1 to suppress stemness and radioresistance of non-small cell lung cancer Mi Tang, Lu Zhang, Jiaxin Zhao, Hongji Dai, Zhiyong Yuan, Zeyun Mi, Zhiqiang Wu
• 2193 · PDF UPP1 promotes cisplatin-induced cancer stem cell enrichment in ovarian cancer via metabolic reprogramming Jessica J. Miao, Linzhou Wang, Ananya Banerjee, Na Li, Yajing Yang, Aidan Li, Kevin Wang, Patrick Stevens, Xiaoli Zhang, Qi-En Wang
• 2194 · PDF A PLK1-OCT4 regulatory axis controls lineage plasticity and neuroendocrine differentiation in prostate cancer Mohammad Esfini Farahani, Yanquan Zhang, Meng Wu, Ruixin Wang, Fatemeh Seilani, Xinyi Wang, Xiaoqi Liu
• 2195 The morphological discovery of the natural killer cells and enhancement of their activity using micellized nutraceuticals Jerry T. Thornthwaite, Olufemi Emmanuel Akanni, Daniel Strasser, Kyle A. Thornthwaite
• 2196 Matrix softness and fluid shear forceact through TRPV4 to promote ovarian cancer stemness, tumorigenicity and metastasis Zhenchuan LEI
• 2197 Mechanistic basis of panobinostat, venetoclax, and anti-CD40 combination therapy in the immune elimination of cancer stem cells Yishu Xu, Juraj Jakubik, Leoni Moldaner, Gautami Atul Gaidhani, Zuzana Tatarova
• 2198 · PDF Targeting Bmi-1 suppresses cancer stemness and tumor growth in mucoepidermoid carcinoma Satoshi Yamada, Kristy Warner, Jaqueline Vaz Vanini, Zhaocheng Zhang, Ririko Tsuboi, Jacques Eduardo Nör
• 2199 · PDF Dissecting ROBO4 function in regulating breast cancer cell plasticity Isobel J. Fetter, Veronica Haro Acosta, Paloma Medina, Shaheen S. Sikandar
• 2200 · PDF The mesenchymal state drives stemness and limits differentiation in glioblastoma Emanuele Filiberto Rosatti, Denise Sighel, Anna Veronese, Toma Tebaldi, Alessandro Quattrone
• 2201 Multidimensional transcriptomic alas of recurrent uterine leiomyosarcomas uncovers stem-like hormonal cells with high drug sensitivity and improved patient outcomes Maria Moozhiyil Korah, James P. Agolia, Biren Reddy, Renceh A. B. Flojo, Amanda Gonçalves, Lilin Wang, Rosyli F. Reveron-Thornton, Chuner Guo, Beatrice Sun, Amanda R. Kirane, George Poultsides, Deshka Foster, R. Stephanie Huang, Gregory W. Charville, Michael T. Longaker, Daniel Delitto
• 2202 · PDF APOBEC3C rewires RNA splicing and self-renewal in hematopoietic stem and progenitor cells Inge van der Werf, Jane Isquith, Emma Klacking, Jessica Pham, Wenxue Ma, Shuvro P. Nandi, Rongjie Wu, Claire Engstrom, Neha Katragadda, Anna A. Khachatrian, Thomas Whisenant, Ludmil Alexandrov, Catriona Jamieson
• 2203 · PDF PSMD2 Suppression Disrupts Autophagy Turnover and Creates an Autophagy-Dependent Vulnerability in ER+ Breast Cancer Yejoo Lee, Ju Hee Kim, So-Youn Jung, Wonshik Han
• 2204 · PDF ID proteins regulate IL-6 expression and cancer stem-like cell features following chemotherapy in ovarian cancer Megan A. Keene, Mikella Robinson, Darren Lighter, Carrie D. House
• 2205 · PDF Isoform-level transcriptome analysis for enriched cancer stem cells from patient-derived ovarian cancer cell lines Rachel S. Perkins, Jisun Kang, Matthew S. Jung, Sue Chin Lee, Wenjing Zhang, Won-Young Choi
• 2206 · PDF Uncovering a pancreatic ductal adenocarcinoma sub-population with stemness and unique therapeutic response SHIFA KHAN, Wen-Cheng Chung, Charles D. Moore, Keli Xu
• 2207 The impact of tumor treating fields (TTFields) on the transcriptome and the secretome of cancer stem-like cells isolated from the sub-ventricular zone of glioblastoma patients Rachel B. Sidebottom, Antonia E. Sajche Sapon, Yamhilette Licon-Munoz, Christian A. Bowers, Sara G.m. Piccirillo
• 2208 MAP2-mediated integrin dysregulation reprograms cancer cell plasticity to drive liver cancer cell transition to a mesenchymal and stemness state in hepatocellular carcinoma Ut Kei Lou, Tin-Lok Wong, Huajian Yu, Ki-Fong Man, Ka-Hei Lam, Jia Jian Loh, Lei Zhou, Yuan Gao, Cheng-Han Yu, Stephanie Ma
• 2209 · PDF RelB drives integrin-mediated stress tolerance and relapse in high-grade serous ovarian cancer Omar Lujano Olazaba, Mikella Robinson, Greg J. Jordan, Sofia Howe, Cassidy Lucht, Anna Platen, Dishant Vandra, Mena Shammas, Katelyn Shelby, Ingrid Niesman, Christina M. Annunziata, Carrie Danielle House
• 2210 Ouabain exerts both anti-tumor and senolytic effects in brain cancer stem and tumor cells Alaa Daoud Sarsour, Gila Kazimirsky, Moran Dvela-Levitt, Chaya Brodie, Heidrun Weidemann, Iris Frid
• 2211 · PDF STAT1 and STAT3 cooperatively control cancer stem cell (CSC) fate and IFNgamma-dependent CSC maintenance Sophia Hidalgo, Anushka Poola, Yipeng Zhang, Rachel Zhou, Kourosh Kouhmareh, Jack D. Bui, Magalie Dosset

在完整检索应用中浏览本分会场 →