Tumorigenesis and Early Microenvironmental Trajectories

• 2252 Resolving the initiating changes in the immunomodulatory glycome during early tumorigenesis of head and neck squamous cell carcinoma in living animals Sarah M. Hammoudeh, Thomas D. Madsen, Roberto Weigert
• 2253 · PDF Multimodal and multikingdom spatial transcriptomics identify bacterial niches implicated in oral cancer development Fushun Chen, Lorena Isabel Gomez, Tieling Zhou, Yuejiang Liu, Inti C. Tarifa Reischle, Sujuan Yang, Manvi Sharma, Jiping Feng, Jaafar Hadi, Fuduan Peng, Yibo Dai, Mhenaz Hossain, Ratna Veeramachaneni, Ansam Sinjab, Sean Anderson, Dhrishit Mangrolia, Deborah Rodriguez, Nadim Ajami, Jennifer Wargo, Adel El-Naggar, Roberto Rangel, Nadarajah Vigneswaran, Linghua Wang, Jeffrey N. Myers, Humam Kadara
• 2254 · PDF 3D multimodal spatial profiling of pre-gastric cancer progression using same-slide RNA-protein and fluorescent H&E Eric Sha, Seock-Jin Chung, Jean R. Clemenceau, Sunho Park, Minji Kim, Inyeop Jang, Youngwon Cho, Seunghyi Kook, Soonyoung Lee, Jongseong Jang, Eunyoung Choi, Tae Hyun Hwang
• 2255 · PDF Spatial transcriptomics reveals evolving tumor microenvironmental archetype along the lung premalignancy-adenocarcinoma continuum Yibo Dai, Fuduan Peng, Ansam Sinjab, Yunhe Liu, Sujuan Yang, Lorena I Gomez Bolanos, Tieling Zhou, Minyue Chen, Alejandra G Serrano, Jianlong Liao, Guangsheng Pei, Yang Liu, Jiahui Jiang, Kyung Serk Cho, Kai Yu, Jiping Feng, Zahraa Rahal, Naoe Jimbo, Takuo Hayashi, Satsuki Kishikawa, Kazuya Takamochi, Avrum Spira, Steven M. Dubinett, Tomoo Itoh, Takashi Yao, Kenji Suzuki, Stephen G. Swisher, Mingyao Li, Junya Fujimoto, Ignacio Wistuba, Jared K. Burks, Kadir Caner Akdemir, Hind Rafei, Katayoun Rezvani, Jeffrey N. Myers, Humam Kadara, Linghua Wang
• 2256 · PDF Age-related transcriptional and alternative splicing changes in lung progenitor cells predisposing to immune dysfunction Mohammed Toufiq, Florentina Marches, Hyeon Gu Kang, Te-Chia Wu, Ryan Englander, Sanaz Keshavarz Shahbaz, Marina Yurieva, Phylip Chen, Mark E Peeples, Adolfo Garcia-Sastre, Michael Schotsaert, Damien Chaussabel, Karolina Palucka, Olga A. Anczukow-Camarda
• 2257 · PDF Single-cell transcriptomic analysis of fallopian tube and ovary to define cell type and BRCA-specific markers Eric F. Medina, Jacob I. Rodriguez, Alyssa Bujnak, Devon Lawson, Kai Kessenbrock
• 2258 · PDF SLC12A2 drives a tumor-promoting microenvironment and poor prognosis in hepatocellular carcinoma by suppressing lipolysis Yotaro Kudo, Ryosuke Tateishi, Mitsuhiro Fujishiro
• 2259 · PDF Reprogramming of the stromal and immune microenvironment in preinvasive breast cancer Siyuan He, Aatish Thennavan, Runmin Wei, Shanshan Bai, Jianzhuo Li, Chante Bethell, Emi Sei, Mitchell Rao, Tapsi Kumar, Chenling Tang, Ivan Marin, Jessica Montalvan, Chandandeep Nagi, Bora Lim, Savitri Krishnamurthy, Alastair Thompson, Nicholas E. Navin
• 2260 · PDF Macrophage immunometabolism as a targetable driver of early lung cancer progression Tyler Faith, Amrita Roy, Dikshaya Prabhakara, Yaron Zaret, Samuel Weinberg, Alicia Hulbert, Frank D. Weinberg
• 2261 · PDF Deciphering the role of macrophages in the development of pancreatic ductal adenocarcinoma Maria F. Wissler, Jessie Kanacharoen, Daniel J. Salas-Escabillas, Shalini Datta, Naziheh Assarzadegan, Eugene Shenderov, Ashley Kiemen, Won Jin Ho, Laura DeLong Wood
• 2262 · PDF Cell division regulates macrophage invasion in mammary epithelia Emily A. Pratt, Mariia Akhmanova
• 2263 Microenvironmental rewiring in giant cell tumor of bone: Stromal lineage hierarchy, immune diversion, and novel osteoclastogenic and angiogenic circuits Chao Zhang, Jilong Yang, Xiangchun Li, Kexin Chen, Hongru Shen, Zhichao Liao
• 2264 · PDF Spatial trajectories and niche rewiring from ground‑glass to solid transition in lung adenocarcinoma Kwon Joong Na, Hongyoon Choi, Jaemoon Koh, Taeyoung Yun, Jihyeon Park, Bubse Na, Samina Park, In Kyu Park, Chang Hyun Kang, Young Tae Kim
• 2265 · PDF Stromal cyclin D1 promotes prostate cancer stemness via the transcriptional regulatory E domain Xuanmao Jiao, Danni Li, Rita Pancsa, Ritika Harish, Zhiping Li, Gideon Tolufashe, Hallgeir Rui, Beatrice S. Knudsen, Yanming Du, Hsin-Yao Tang, Peter Tompa, Richard G. Pestell
• 2266 · PDF Unexpected role of nuclear receptor CAR in cholangiocarcinoma development Inyoung Cheon, Ji Ho Suh, Mi Jeong Heo, Sung Ho Lee, Hyun-Jung Jung, Young-Ho Ahn, David D. Moore, Kang Ho Kim
• 2267 · PDF Microenvironmental CTHRC1 has a pro-tumorigenic role in colorectal cancer Haylee Duval, Barbara Toomey, Michelle Karam, Brian Nestor, Sergey Ryzhov, Volkhard Lindner, Michaela Reagan
• 2268 · PDF Elucidating the role of p21 + senescent cells in early-stage lung tumorigenesis Yuanning Du, Luis I. Prieto, Karthikbabu Jeganathan, Cheng Zhang, Hu Li, Darren Baker
• 2269 · PDF Two-step mechanism of plexiform neurofibroma formation: Role of the NF-κB pathway in neurofibroma formation Ramya Ravindran, Noemi Kedei, Eui-Kyung Youn, Kwangmin Choi, Avery Volz, Jay Pundavela, David A. Largaespada, Jack F. Shern, Nancy Ratner
• 2270 · PDF A MUC1-overexpressing epithelial population is associated with CDH1 loss-of-function gastric adenocarcinoma Chuner Guo, Rosyli F. Reveron-Thornton, Xiaomo Li, James P. Agolia, Maria Moozhiyil Korah, Peter Yuxin Xie, Amanda Gonçalves, Angela Tabora, Lily Xia, Natali Barakat, George Poultsides, Byrne Lee, Amanda R. Kirane, Deshka Foster, Michael T. Longaker, Gregory W. Charville, Daniel Delitto
• 2271 · PDF p53-null cells act as supercompetitors in gastroesophageal tumor initiation Kyle LaBella, Efren Reyes, Mathijs Verhagen, Priyanka Kulkarni, Shadi Tarazi, Shawn Gillespie, Oana Ursu, Louis Vermeulen
• 2272 · PDF Dichotomous immunogenetic landscape of lung adenocarcinoma associated with usual interstitial pneumonia Akifumi Mochizuki, Ayako Suzuki, Kouya Shiraishi, Masahiro Torasawa, Takayuki Honda, Susumu Kirimura, Yasunari Miyazaki, Kenichi Okubo, Syuzo Kaneko, Yukihiro Yoshida, Shun-ichi Watanabe, Masahiro Tsuboi, Genichiro Ishii, Issei Imoto, Ryuji Hamamoto, Yasushi Yatabe, Yutaka Suzuki, Takashi Kohno
• 2273 · PDF Obesogen co-exposure promotes triple-negative breast cancer growth via adipocyte-mediated mechanisms Sarah M. Bernhardt, Mikella Robinson, Carrie House
• 2274 · PDF Cigarette smoke-induced sphingosine-1-phosphate drives cancer-associated fibroblasts activation and esophageal cancer carcinogenesis Xinying Yue, Jialing Ma, Zifei Yang, Yutong Wu, Qianqian Su, Lina Song, Miaoxin Pan, Dongxu Li, Qingyi Liu, Shasha Liu, Yueping Li, Shaokai Zhang, Siyuan Wang, Li Zhang, Ni Zhang, Wei Ping, Catherine C. L. Wong, Dongxin Lin, Chen Wu, Jiang Chang
• 2275 · PDF Biological impact of nanoplastics on the tumor microenvironment Tetsuya Fukui, Ryota Sumitomo, Kosuke Tanaka, Toshi Menju

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