Large Language Models in the Clinic

• 2737 · PDF Real-world usability of a clinical trial knowledge platform in a community cancer network Tony Kin Wai Hung, Shriya Amara, Paulette Schwartz, Aanshi Thumar, Zaid Raza, Elizabeth O’Brien, Gilad Kuperman, Barry Stein, Peter Yu, Jun J. Mao
• 2738 · PDF From chaos to columns: High-accuracy clinical data extraction with CIDER Mate Posta, Aida Figler, Zsofia Dobolyi, Balazs Gyorffy
• 2739 · PDF Evaluation of large language models for automated clinical trial matching in oncology Aakash Desai, Ellen McNeeley, Sanad Alhuski, Maya Khalil, Matthew Might, Rebecca Arend, Andrew Crouse, Mehmet Akce
• 2740 · PDF Applications of large language models to CAR-T cell therapy clinical data using Google cloud computing Emmanuel Contreras Guzman, Matthew Jankowski, Andre De Menezes Silva Corraes, Malvika Gupta, Monica L. Shaw, Madiha Iqbal, Talal Hilal, Saurabh Chhabra, Ricardo Daniel Parrondo, Jody K. Mclean, Kim R. Riester, Kayla Joseph, Melinda Tan, Holly Ross, Cleyonia Barnett, Sylvia Carter, Semy Girmay, Rachel Wolan, Milana Ramsey, Christian Downhour, Kristy Morgan, Shae Sibley, Erica Rushing, Lucy Holmes, Allison Burgstahler, Stephen M. Ansell, Hassan Alkhateeb, Matthew Hathcock, Ramona Bruno, Allison C. Rosenthal, Hemant Murthy, Patrick B. Johnston, Jonas Paludo, Yi Lin
• 2741 · PDF Large language model-based triage of Hematology/Oncology patient messages: Performance, safety, and clinical implications Dinh Nguyen, Sinjin Lee, Brett Anwar, Mason Kellogg, Ronil Synghal, Khang Nguyen
• 2742 An artificial intelligence domain-specialized scalable and clinically relevant pipeline to automate standardized O-RADS stratification for imaging reports in ovarian cancer Asmi Agarwal, Min Ren, Jingjing Gong, Richard Selinfreund, Ruchika Goel, Yanhui Guo
• 2743 · PDF Deploying artificial intelligence driven digital pathology for real world clinical decision-making in pancreatic cancer Ashish Manne, Alejandro Leya, Abdul Rehman Akbar, Upender Manne, Anne Noonan, Anup Kasi, Ashwini Esnakula, Ravi Paluri, Anil Vasdev Parwani, Muhammad Khalid Khan Niazi
• 2744 · PDF Automating clinical and pathological staging for breast cancer patients Arshad Mohammed, Umair Ayub, Pooja Advani, Shakeela W. Bahadur, Amye J. Tevaarwerk, Tufia C. Haddad, Elisabeth I. Heath, Brenda J. Ernst, Ben Zhou, Cui Tao, Sara J. Holton, Karthik V. Giridhar, Irbaz B. Riaz
• 2745 · PDF Patients prefer ChatGPT to physician responses in cancer communication Aaron Segura, Bernard Tawfik, Ben Liem, Zoneddy Dayao, David Y. Lee, Jacklyn M. Nemunaitis, David Savage, Moises Harari-Turquie, Nicole Hill, Charles Foucar, Amy Tarnower, Dulcinea Quintana, Jude Khatib, Thomas Schroeder, Martha Mapalo, Yolanda Sanchez, Ramesh Gopal
• 2746 · PDF AI vs human abstraction of pain scores and analgesic trends in low-dose radiation therapy for osteoarthritis: A concordance study Camille Schwartz, Michael Anderson, Kelsey Moakler, Bradley Newby, David Davenport, Matthew Schwartz
• 2747 · PDF Source discipline matters: Guideline anchored large language model outperforms Open Evidence for decision support in acute leukemias Peter Palumbo, Connor Yost, Emilio Del Toro, Demetrios Garbis, Peter Odutola, Yash Kumar, Arturo Loaiza, Matthew Sullivan
• 2748 Arkangel AI, OpenEvidence, ChatGPT, Medisearch: Are they objectively up to medical standards? A real-life assessment of LLMs in healthcare Natalia Castano -Villegas, Maria Camila Villa, Katherine Monsalve, Isabella Llano, Laura Velásquez, Jose Zea
• 2749 Towards a foundation model for treatment-related adverse events in cancer immunotherapy Bin Baek, Tingyi Li, Biwei Cao, Xiaqing Yu, Xuefeng Wang
• 2750 · PDF Rapid curation of colon cancer cohorts using on-site peta-scale language model for MSI classification from pathology reports Joshua Jay Levy, Nathalie Nguyen, Minh-Khang Le, Keluo Yao, Jane Figueiredo
• 2751 · PDF Large language model-derived molecular patient similarity from real-world MTB data Sophie Lugani, Oğuz Serbetci, Alexander Reinicke, Benedikt Körtum, Berkay Özdin, Thomas Debertshäuser, Dominik Modest, Ulrich Keilholz, Ulf Leser, Manuela Benary
• 2752 · PDF CancerSTFormer enables multi-scale analysis of spot-resolution spatial transcriptomes and dissects the gene and immune regulatory responses of targeted therapies Benjamin Strope, Dana Varghese, William Bowie, Stacy Wang, Qian Zhu
• 2753 · PDF Ontology-guided hierarchical cell typing with large language models for analyzing tumor microenvironment Jeongbin Park, Yuchang Seong, Hongyoon Choi
• 2754 · PDF VGL: Vision-Gene-Language multimodal LLM integrating histopathology and gene expression for cell type classification in lung cancer Haenara Shin, Dongjoo Lee, Jeongbin Park, Hongyoon Choi
• 2755 · PDF Large scale extraction of adverse events by large language models uncovers latent structure of treatment toxicity John Lazar, Divneet Mandair, Catherine C. Smith, Travis Zack
• 2756 · PDF Development of an LLM framework for analysis of heterogeneous breast cancer patients genomic reports Krishna Rani Kalari, Xiaojia Tang, Thanmayee Boyapati, Tanya L. Hoskin, Sumathilatha Myla, Sumedha G. Penheiter, Richard M. Weinshilboum, Liewei Wang, Hamid R. Tizhoosh, Karthik Vikram Giridhar, Matthew P. Goetz, Judy C. Boughey
• 2757 · PDF Scale meets Speed: A transcriptome-wide spatial analysis that runs a rapid and interactive hypothesis-driven workflow with AtoMx ® SIP Evelyn R. Metzger, Patrick Danaher, Nicole Ortogero, Sayani Bhattacharjee, Prajan Divakar, Joseph M. Beechem
• 2758 · PDF PAX3/7::FOXO1 fusion detection and transcriptomic prediction from whole-slide images of rhabdomyosarcoma using attention-based deep learning frameworks: A multi-institutional study Dorsa Ziaei, Hyun Jung, Philip J. Lupo, Pagna Sok, Jack F. Shern, Corinne M. Linardic, Syed Abbas Bukhari, Hsein-Chao Chou, Jun S. Wei, Curtis Lisle, Uma Mudunuri, Javed Khan
• 2759 · PDF An innovative AI-based platform for antibody stability improvement and affinity optimization Yiran Li, Hao Peng, Xinyu Bian, Hui Zhao, Yang Li, Panpan Zhang, Jinying Ning, Feng Hao
• 2761 · PDF Large language model-derived re-contextualization reveals functional landscapes across cancers Yibing Guo, Yanhao Tan, Chien-Hung Shih, Li-Ju Wang, Yu-Chiao Chiu
• 2762 · PDF LLM-based extraction of immunotherapy toxicities reveals severity-dependent effects on overall survival Zeyun Lu, Mustafa Saleh, Charles Lu, Intae Moon, Razane El Hajj Chehade, Elio Ibrahim, Yevgeniy R. Semenov, Toni K. Choueiri, Alexander Gusev
• 2763 · PDF Leveraging large language models to classify pathology reports into ontological hierarchies Brenda Fried, Ali Kamali, Cesar Colorado-Jimenez, Melissa Pulitzer, David Kim, Leonardo Boiocchi, Alexander Chan, Mariko Yabe, Mikhail Roshal, Syed Aijazuddin, Ahmet Dogan, Chad Vanderbilt, Khawaja Hassan Bilal, Gregory Goldgof
• 2764 · PDF Maximizing high-risk incidental pulmonary nodule referrals using artificial intelligence Ivan M. Marrufo, Raymond Johnson, Samuel Newman, Paras Patel, Kalyani Narra
• 2765 · PDF Microbiome foundation modeling of cancer: MiFM-derived continuous trajectories and risk clocks for pan-cancer immunotherapy response prediction Hongru Shen, Yajing Bi, Yan Zong, Zhangyan Lyu, Chao Zhang, Kexin Chen, Xiangchun Li
• 2766 · PDF Self-supervised learning defines a universal biomarker of malignancy in platelet RNA Hongru Shen, Yan Zong, Yajing Bi, Jilei Liu, Chen Lyu, Fangyu Shi, Yichen Yang, Meng Yang, Yang Li, Kexin Chen, Xiangchun Li

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