Natural Products

• 3642 · PDF Capsaicin-nanoparticles sensitize human squamous cell lung cancer towards the growth-inhibitory activity of paclitaxel Amanda M. Sugrue, Kushal J. Modi, Reagan S. Light, Kaitlyn B. Conley, Sarah L. Miles, Piyali Dasgupta
• 3643 · PDF The combination of actinomycin D and resveratrol induces synergistic anticancer activities against aerodigestive tract cancers Raji M. Lukmon, Jihan F. Amin, A.R.M. Ruhul Amin
• 3644 · PDF Chromomycin A2 disrupts leukemia cell viability via integrated autophagic and apoptotic programs Keli Lima, Emilly O. Vieira, Rita C. Cavaglieri, Frederico L. Nogueira, Glaucia M. Machado-Santelli, Leticia V. Costa-Lotufo, Eduardo M. Rego, João A. Machado-Neto
• 3646 · PDF Differential mechanisms of MCF-7 cytotoxicity by oleuropein and punicic acid and the role of oxidative stress and peroxiredoxin antioxidants Samantha Diiorio, Braden Quitmeyer, Shelley A. Phelan
• 3647 Combining optimally synthesized quercetin analogs with BRAF inhibitors as a novel synergistic approach to treat melanoma Ahlam Armaly, Paige Toran, Victoria Del Gaizo Moore
• 3648 · PDF Luteolin inhibits DNA methyltransferase 1 and alpha 6-integrin gene expression to suppress proliferation and stemness in breast cancer cells from patients of West African ancestry Michael H. Hall, Mya St. Louis, Ozichi Amobi, John Olanrewaju, Shawneee Angeloni, Ubaldo Soto, Eileen Brantley
• 3649 · PDF High-throughput screening of natural products discovers inhibitors of ribosome biogenesis Garrett Kimble, Michael Buszczak, Mark J. Henderson, Vincent Tagliabracci, Monagna Jarajapu, Bruce Posner, Barry R. O'Keefe, Sara Sanders
• 3650 · PDF Evaluating the immunomodulatory role of celastrol in murine acute graft versus host disease after allogeneic hematopoietic stem cell transplantation Tara Chand Yadav, Yogamaya Divakar Prabhu, Vasantharaja Raguraman, Shanid Mohiyuddin, Venkatesh Rajamanickam, Ibrahim Mohammed, Deepthi Rao, Gerhard C. Hildebrandt, Senthilnathan Palaniyandi
• 3651 · PDF Carnosic acid induces ROS and activates ASK1 signalling in NSCLC cells Eric J. O'Neill, Evangelia Tsiani
• 3652 · PDF Thymoquinone blocks pancreatic ductal adenocarcinoma growth by altering novel circRNAs and miRNAs Bin Bao, Irfana Muqbil, Md Hafiz Uddin, Yang Shi, Yin Wan, Adeeb Aboukameel, Ramzi M. Mohammad
• 3653 · PDF Screening of natural products library against 5-lipoxygenase (5-LOX) and mPGES1 proinflammatory targets for CRC interception Krishnendu Goswami, Nataliya Smith, Ravi Manjhi, Gopal Pathuri, Brandon Somerville, Yurong Song, Venkateshwar Madka, Kajal Biswas, Altaf Mohammed, Robert H. Shoemaker, Matthew J. Hart, Chinthalapally V. Rao
• 3654 Plant-derived exosomes from black soybeans for combatting pancreatic and colon cancer cells Zhangzhu Ruixian, Makiko Nakahana, Yasuyuki Shimizu, Mohammed Salah, Hiroaki Akasaka, Hiroki Kawaguchi, Tomoya Ishida, Qin Qin, Qu Zhang, Takeaki Ishihara, Daisuke Miyawaki, Ryohei Sasaki
• 3655 · PDF Dose-dependent anti-proliferative activity of a bioactive hemp-derived extract REPYR-SC1 against prostate cancer Joel Costoya, Joaquin J. Jimenez
• 3656 · PDF A-ring analogs of Andrographolide inhibit wnt1 signaling and exhibit potent anticancer activity in breast and colorectal cancer models Rushika Raval, Selina Xi, Ruirui Liu, Abigail Yee, Aileen Pak, Edward Njoo, Gary Johanning, Feng Wang-Johanning
• 3657 · PDF Preclinical discovery of proscillaridin A glycan analogs for the in vitro and in vivo treatment of solid tumors Shreya Somani, Lekhya Menta, Gary Johanning, Feng Wang-Johanning, Edward Njoo
• 3658 · PDF C-4 analogs of podophyllotoxin inhibit tubulin polymerization: A generalizable platform for the discovery of antimitotic therapeutics for cancer Shreya Somani, Stella Yang, Lekhya Menta, Yining Xie, Anna Gribok, Evy Hsen, Edward Njoo, Gary Johanning, Feng Wang-Johanning
• 3659 · PDF Heterogeneous expression and cancer-selective regulation of endogenous membrane TRAIL by quercetin across various human cancer cell lines Erin Marie Thorpe, Candece L. Gladson, Michael Kalafatis, Center for Gene Regulation in Health and Disease (GRHD), Cleveland State University, Cleveland, OH
• 3660 · PDF Network pharmacology reveals functional components and molecular mechanisms of andrographis combined with lactoferrin in pancreatic cancer treatment Yuan Li, Wenhao Weng, Ajay Goel
• 3661 · PDF Discovery of Spondias mombin flavonoid rutin as a novel DNA methyltransferase 1 inhibitor and potential agent to treat triple negative breast cancer in patients of West African ancestry Afees John Olanrewaju, Elyssa Fraser, Joseph Enya, Leviticus Arietarhire, Ezekiel Olugbogi, Toluwanimi Afolabi, Oladimeji Soremekun, Michael Hall, Ozichi Amobi, Victor Chinedu, John Khalaf, Jonathan De Anda, Shawnee Angeloni, Ubaldo Soto, Eileen J. Brantley
• 3662 · PDF Activity profiling of natural compounds identifies potent chemotypes active in parental and drug-resistant lymphoma models Filippo Spriano, Francesca Ghirga, Deborah Quaglio, Mattia Mori, Alberto J. Arribas, Bruno Botta, Francesco Bertoni
• 3663 · PDF Antiproliferative screening in B cell lymphoma: Ghanaian medicinal plants and their phytochemical correlates Filippo Spriano, Alberto J. Arribas, Alberto Furlan, Johnson Nketiah, Barbara Z. Anibea, Andrea Cavalli, Afua A. Mensah, Dorcas Osei-Safo, Francesco Bertoni
• 3664 · PDF A novel 4-herb traditional Chinese medicine formula inhibits metastasis of triple-negative breast cancer Longling Wang, Julia K.M. Lee, Judy Y.W. Chan, Zhong Zuo, Kenneth K.W. To
• 3665 · PDF Oleuropein, a phenolic compound from olive leaves, exerts cytotoxicity and peroxiredoxin induction in MDA-MB-231 breast cancer cells Giovanna Kalin, Adam Vaz, Shelley A. Phelan
• 3666 · PDF Antitumor effects of coffee diterpenes, kahweol acetate and cafestol, on taxane-resistant and neuroendocrine prostate cancer cells Tomohiro Hori, Hiroaki Iwamoto, Taiki Kamjima, Hiroshi Kano, Makino Tomoyuki, Renato Naito, Hiroshi Yaegashi, Kazuyoshi Shigehara, Takahiro Nohara, Kouji Izumi, Atsushi Mizokami
• 3667 · PDF Neohesperidin dihydrochalcone: A novel natural inhibitor of ferroptosis Bomi Han, Yi-Xi Gong, Seonghye Son, Eui Man Jeong
• 3668 Targeting apoptotic machinery using methanolic extracts of Carpobrotus edulis to suppress pancreatic cancer growth Lesetja Motadi, Ronald Makalapetlo
• 3669 · PDF Oleuropein downregulates MITF via direct PKA inhibition and ERK-mediated turnover in melanoma Ingyu Lee, Jihye Kim, Yi-Xi Gong, Eui Man Jeong
• 3670 · PDF Beta-lactams, structural mimics of natural products, as anti-pancreatic cancer agents: A pilot study Debasish Bandyopadhyay, Tushar Debnath, Attrayo Mukherjee, Jonathan Rock, Omar Espino, Vivek Kumar Kashyap, Subhash C. Chauhan

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