Liquid Biopsies: Circulating Nucleic Acids 3

• 3840 · PDF Detection of minimal residual disease in colorectal cancer patients after surgery through circulating tumor DNA profiling Luis Maya Janssen, Ekaly Apagnha, Flávio de Alencar Teles Barreto, André Araújo de Medeiros Silva, Mayra Veloso Ayrimoraes Soares, João Batista de Sousa, Fabio Pittella-Silva
• 3841 · PDF Prognostic significance of PI3K-AKT pathway alterations identified by ctDNA sequencing in metastatic castration-resistant prostate cancer DongSoo Kyung, Yongjun Cha, Chang Wook Jeong, Seung-hwan Jeong, Chel Lee, Won Yeong Ko, Jee-Soo Lee, Moon-Woo Seong, Cheol Kwak, Tae-You Kim
• 3842 Non-invasive cfDNA methylation profiling for prediction of PD-L1 tumor proportion score status in NSCLC Wei Tian, Anton Valouev, Kunwar Singh, Matthew Ellis, Katie Quinn, Tingting Jiang, Martina Lefterova, Justin Odegaard, Darya Chudova
• 3843 · PDF Sequencing full-length mRNA in whole blood of breast cancer patients for antibody-drug conjugate therapy selection Jacob Bradley, Gabriel Benitez, Mark Barnett, Oliver Eve, Ivalya Ivanova, Katrina Morris, Alice Séguret, Ahmad Zyoud, John Davey, Yuanyuan Cheng, Amy Robinson, Arran Turnbull, Mike Dixon, Han-Yu Chuang, Rick Hockett, Richard Kuo, Pamela N. Munster
• 3844 · PDF Longitudinal ctDNA monitoring in melanoma using highly multiplexed USE-PCR incorporating bespoke targets enables real-time detection of treatment response and recurrence Hunter Miller, Annalara Fischer, Melissa Hall, Michael E. Egger, Kavitha Yaddanapudi, Lucien Jacky, John Alvarado, Aaron Aguiar, Nathaniel Clark, Paul Belitz, Jeremy Myslinski, Jerrod Schwartz, Paul Flook, Mark Linder
• 3845 · PDF Enhancing MRD detection through an ultrasensitive ctDNA test: Insights from real-world clinical data Rachel Marty Pyke, Steven Dea, Sherif El-Refai, Fábio C. P. Navarro, Charles W. Abbott, Yi Chen, Janet Lai, Gabor Bartha, John M. Lyle, Jason Harris, Vijay Gunuganti, Sean M. Boyle, Richard O. Chen
• 3846 · PDF Short double-stranded cfDNA: A novel precision biomarker class for cancer diagnostics Mirko Sonntag, Zhoutao Zhang, Denise Leupold, Jan Mueller, Yevhen Vainshtein, Christina Hartwig, Georg F. Weber, Kai Sohn
• 3848 · PDF Urine cell-free DNA methylation-based deconvolution identifies tumor-specific cell types in localized urinary tract cancers Ze Zhang, Rashad Nawfal, Gunsagar Gulati, Damien Vasseur, Ji-Heui Seo, Hunter Savignano, Razane El Hajj Chehade, Karl Semaan, Tamara Merhej, John Canniff, Noa Phillips, Ning Shen, Phillip Adams, Ilana Epstein, Jack Horst, Alexis Zinselmeier, Rachel Throwbridge, Gwo-Shu Mary Lee, Jamil Azzi, Michelle S. Hirsch, Martin Kathrins, Timothy N. Clinton, Matthew Mossanen, Keegan Korthauer, Toni K. Choueiri, Matthew L. Freedman, Sylvan C. Baca
• 3849 · PDF Frequent monitoring of NSCLC immunotherapy using an mDETECT liquid biopsy reveals unexpected complexity and opportunities Mihaela Mates, Andrew Robinson, Harriet Feilotter, Sofia Genta, Keira Frosst, Keira Parr, Garrett Baron, Christopher R. Mueller
• 3850 · PDF Liquid biopsy-based monitoring of disease status in patients with HPV-positive oropharyngeal carcinoma (OPSCC) Jens Peter Klussmann, Oliver Siefer, Zurwa Merrjam Uzun, Jannik Johannsen, Dustin Firmenich, Nora Wuerdemann, Ernst J.M. Speel, Julie George
• 3851 · PDF Ultrasensitive ctDNA monitoring predicts early response of immunotherapy in recurrent metastatic non-small cell lung cancer Kishen R. Patel, Bailiang Li, Charles W. Abbott, Cristina Naceur-Lombardelli, Sadegh Saghafina, Sevasti Galani, James R. M. Black, Wing Liu, Nicola Steele, Gillian Price, Shobhit Baijal, Dean Fennell, Matthew G. Krebs, Tanya Ahmad, Alexandra Pender, Siow M. Lee, Mariam Jamal-Hanjani, Nicholas McGranahan, Allan Hackshaw, Sean Michael Boyle, Richard O. Chen, Charles Swanton, Crispin T. Hiley
• 3852 · PDF Ultrasensitive AI-driven framework for MRD detection based on multidimensional cfDNA features Yunfei Shi, Hao Zhang, Zexiao Lin, Ningyou Li, Maolong Wang, Hua Bao, Jinfeng Zhang, Zhili Chang, Yong Ge, Peng Li, Pan Wang, Liang Huang, Xiangming Liu, Lu Han, Wangming Ji, Teng Sun, Dujun Hua, Xunbiao Liu, Mingya Wang, Baihan Zhu, Dongqin Zhu, Xue Wu, Haimeng Tang, Hao Zhang, Yang Shao
• 3853 · PDF Genomic profiling of circulating tumor DNA in endometrial cancer in Asia: A-TRAIN study Hiroki Tamura, Yuki Kojima, Kazuki Sudo, Wan Zamaniah Wan Ishak, Marcelo S. Imasa, Arb-aroon Lertkhachonsuk, Ryoka Miki, Hiroshi Yoshida, Shinji Kohsaka, Yukari Nagasaka, Ryunosuke Machida, Tetsuya Sasaki, Tomomi Hata, Kenichi Nakamura, Kan Yonemori
• 3854 · PDF Plasma cell-free RNA transcriptome analysis reveals transcriptional dysregulation and immune remodeling in pancreatic ductal adenocarcinoma Gyuryang Park, Hyosil Kim, Tae Young Kim, Sung Joon Kim, Jin-Hwa Park, Baeki E. Kang, Jung Won Chun, Sung-Sik Han, Tae Min Kim, Sang Myung Woo
• 3855 Circulating DNA methylation signatures enable early detection of gastrointestinal cancers Ruo-Kai Lin, YAO-YU HSIEH
• 3856 · PDF Detection of cfDNA shedding from advanced precancerous lesions Fei Lu, Liliana Cerna, Spenser Alexander, Noura Tbeileh, Esha Atolia, Dina Hafez, Eser Kirkizlar, Matthew Rabinowitz, Alexey Aleshin, Trupti Kawli
• 3857 · PDF Comprehensive profiling of circulating tumor DNA in blood enables sensitive detection and genomic characterization of HPV cancer and precancer Qin Wang, Samuli Eldorfs, Sangmi Sandra Lee, Yana Al-Inaya, Gjystina Lumaj, Eliana Epstein, Dipon Das, Emma Ricart, Harsharan Dhillon, Juniper Lake, Michael G. Drage, Shun Hirayama, Viktor Adalsteinsson, Benjamin T. Davis, Doga C. Gulhan, Daniel Faden
• 3858 · PDF Methylation profiling of cell free DNA using EMSeq whole genome sequencing and a targeted methylome panel for classification of pediatric ocular and brain tumors Laura A. T. Kagami, David N. Buckley, Jesse L. Berry, Susan N. Chi, Xiaowu Gai, Erin Kiehna, Katrina O’Hollaran, Dejerianne Ostrow, Tom Rosenberg, Yan Chen Wongworawat, Liya Xu, Jaclyn Biegel
• 3859 · PDF Dynamic systemic immune modulation in metastatic neuroendocrine tumor (NET) patients treated with targeted alpha-emitter 212 Pb-DOTAMTATE AlphaMedix Alessandra Jordano Conforte, Izabela Tworowska, Sara Fonseca Costa, Marta Brzezinska, Amaia Martinez Usatorres, Noushin Hadadi, Sylvain Monnier-Benoit, Simona Pavan, Rouzbeh Esfandiari, Brian Hashemi, Pedro Romero, Ebrahim S. Delpassand
• 3860 · PDF A low-cost bioassay for multi-cancer detection in cfDNA using quantitative methylation-specific PCR Emily Neaga, Sarah Falotico, Mayur Gurnani, Miguel Williams, Anthony Shuber
• 3861 · PDF Low-cost detection of advanced adenomas in cfDNA using quantitative methylation-specific PCR Emily Neaga, Sarah Falotico, Mayur Gurnani, Miguel Williams, Anthony Shuber
• 3862 · PDF Convergent chromatin remodeling enables pan-aerodigestive detection of advanced malignancies in plasma cfDNA Axel Misael Hidalgo, Ayesha Hashmi, Jeff Szymanski, Pradeep Chauhan, Lilli Greiner, Faridi Qaium, Daniel J. Ma, David M. Routman, Katie M. Van Abel, Aadel A. Chaudhuri
• 3863 · PDF Enhanced cfDNA fragmentation-based treatment monitoring on the Ultima Genomics platform Laurel K. Millberg, Garrett Graham, Zachary Skidmore, Jordan Gumm, Kevin Jacobs, Ariel Jaimovich, Elena Helman, Bryan Chesnick, Roberto Olivares-Amaya, Timothy Mcdaniel, Sian Jones, Amoolya Singh, Lorenzo Rinaldi
• 3864 · PDF Serial ctDNA monitoring in metastatic breast cancer using an ultrasensitive tumor informed structural variant based assay Mitchell J. Elliott, June Roh, Kareena Thakur, Sasha Main, Karen Howarth, Sofia Birkeälv, Jennifer Yen, Völundur Hafstad, Wendy Levin, Vikash Kumar, Long Nguyen, Meredith Li, Scott Victor Bratman, Eitan Amir, Philippe L. Bedard, Lillian L. Siu, Hal Berman, David Cescon

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